2-PHOSPHOENOL PYRUVATE NA3SALT Property

Melting point:

33-37°C

storage temp. 

−20°C

solubility 

H₂O: 0.1 g/mL, clear to slightly turbid, colorless

form 

Powder

CAS DataBase Reference

5541-93-5

EPA Substance Registry System

2-Propenoic acid, 2-(phosphonooxy)-, trisodium salt (5541-93-5)

Safety

Hazard Codes 

F,Xi

Risk Statements 

36/37/38

Safety Statements 

22-24/25-36-26

WGK Germany 

3

F 

9

TSCA 

Yes

HS Code 

29319090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-PHOSPHOENOL PYRUVATE NA3SALT Chemical Properties,Usage,Production

Chemical Properties

white to almost white powder

Uses

When coupled with pyruvate kinase it completes an ATP-regenerating system

Uses

Phospho(enol)pyruvic acid trisodium salt hydrate has been used in:

• several enzyme activity assays, such as PRPP synthetase (PRPPS) assay, ribokinase (RK) assay, adenine phosphoribosyltransferase (APRT) assay
• in the reaction mixture for enzyme kinetic assay to determine platelet-derived growth factor receptor α (PDGFRA) kinetic parameters
• as a component in buffer B to react with adenosine diphosphate (ADP) to form adenosine triphosphate (ATP) for energy charge measurement

Biochem/physiol Actions

Phosphoenolpyruvic acid plays a major role in the initial step of glycolysis by acting as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase.