H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH
- Product Name
- H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH
- CAS No.
- 144189-71-9
- Chemical Name
- H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH
- Synonyms
- Aβ22-35;EDVGSNKGAIIGLM;β-Amyloid 22-35;BETA-AMYLOID (22-35);H-EDVLGSNKGAIIGLM-OH;Bate-Amyloid (22-35);Amyloid Peptide (22-35);AMyloid b-Protein (22-35);Amyloid β-Protein (22-35);Amyloid β-Protein (22-35)
- CBNumber
- CB2279677
- Molecular Formula
- C59H102N16O21S
- Formula Weight
- 1403.6
- MOL File
- 144189-71-9.mol
H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH Property
- Boiling point:
- 1805.7±65.0 °C(Predicted)
- Density
- 1.289±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble in DMSO
- pka
- 3.24±0.10(Predicted)
- form
- Solid
- Sequence
- H-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- A5080
- Product name
- Amyloid β-Protein Fragment 22-35
- Purity
- ≥95% (HPLC)
- Packaging
- 1mg
- Price
- $363
- Updated
- 2025/07/31
- Product number
- CS-0044411
- Product name
- β-Amyloid(22-35)
- Packaging
- 1mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FA108571
- Product name
- Amyloid beta-Protein (22-35)
- Packaging
- 1mg
- Price
- $98
- Updated
- 2021/12/16
- Product number
- FA108571
- Product name
- Amyloid beta-Protein (22-35)
- Packaging
- 2mg
- Price
- $171
- Updated
- 2021/12/16
- Product number
- CS-0044411
- Product name
- β-Amyloid(22-35)
- Packaging
- 5mg
- Price
- $280
- Updated
- 2021/12/16
H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH Chemical Properties,Usage,Production
Uses
β-Amyloid 22-35 (Amyloid β-Protein 22-35), the residues 22-35 fragment ofβ-amyloid protein, has a cytotoxic effect on cultured neurons from the rat hippocampus in serum-free medium. β-Amyloid 22-35 forms aggregates and typical amyloid fibrils resembling those of the β-amyloid protein in neutral buffer solution)[1].
Biological Activity
Has cytotoxic effect on cultured neurons from r at hippocampus in serum free medium. Also forms aggregates and fibrils similar to those of β-amyloid protein in senile plaque cores.
References
[1] Takadera T, et al. Toxic effect of a beta-amyloid peptide (beta 22-35) on the hippocampal neuron and its prevention. Neurosci Lett. 1993 Oct 14;161(1):41-4. DOI:10.1016/0304-3940(93)90135-8
[2] Zhou WW, et al. Decreasing oxidative stress and neuroinflammation with a multifunctional peptide rescues memory deficits in mice with Alzheimer disease. Free Radic Biol Med. 2014;74:50-63. DOI:10.1016/j.freeradbiomed.2014.06.013
H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH manufacturers
- Product
- Bate-Amyloid (22-35) 144189-71-9
- Price
- US $0.10-0.30/kg
- Min. Order
- 1kg
- Purity
- >98%
- Supply Ability
- 20 tons
- Release date
- 2024-01-09
- Product
- Amyloid Bate-Protein (22-35)/Bate-Amyloid (22-35) 144189-71-9
- Price
- US $0.10-0.30/kg
- Min. Order
- 1kg
- Purity
- >98%
- Supply Ability
- 20 tons
- Release date
- 2024-01-10