Methyl 4-ketocyclohexanecarboxylate
- Product Name
- Methyl 4-ketocyclohexanecarboxylate
- CAS No.
- 6297-22-9
- Chemical Name
- Methyl 4-ketocyclohexanecarboxylate
- Synonyms
- 4-OXO-CYCLOHEXANECARBOXYLIC ACID METHYL ESTER;NSC 17321;4-carbomethoxycyclohexanone;4-(Methoxycarbonyl)cyclohexanone;Methyl 4-cyclohexanonecarboxylate;methyl 4-oxocyclohexancarboxylate;Methyl cyclohexanone-4-carboxylate;METHYL 4-KETOCYCLOHEXANECARBOXYLATE;4-CYCLOHEXANE CARBOXYLIC ACID METHYL ESTER;4-Oxocyclohexane-1-carboxylic acid methyl ester
- CBNumber
- CB2282868
- Molecular Formula
- C8H12O3
- Formula Weight
- 156.18
- MOL File
- 6297-22-9.mol
Methyl 4-ketocyclohexanecarboxylate Property
- Boiling point:
- 96-97 °C(Press: 8.0 Torr)
- Density
- 1.11g/ml
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- soluble in Chloroform, Methanol
- form
- Oil
- color
- Clear Colourless
- InChI
- InChI=1S/C8H12O3/c1-11-8(10)6-2-4-7(9)5-3-6/h6H,2-5H2,1H3
- InChIKey
- BLYKGTCYDJZLFB-UHFFFAOYSA-N
- SMILES
- C1(C(OC)=O)CCC(=O)CC1
Safety
- HS Code
- 2918300090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M315045
- Product name
- Methyl4-Oxocyclohexanecarboxylate
- Packaging
- 2g
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 114724
- Product name
- Methyl 4-oxocyclohexanecarboxylate
- Purity
- 97%
- Packaging
- 5g
- Price
- $188
- Updated
- 2021/12/16
- Product number
- W7499
- Product name
- Methyl4-oxocyclohexanecarboxylate
- Packaging
- 5g
- Price
- $49
- Updated
- 2021/12/16
- Product number
- 114724
- Product name
- Methyl 4-oxocyclohexanecarboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $57
- Updated
- 2021/12/16
- Product number
- W7499
- Product name
- Methyl4-oxocyclohexanecarboxylate
- Packaging
- 10g
- Price
- $81
- Updated
- 2021/12/16
Methyl 4-ketocyclohexanecarboxylate Chemical Properties,Usage,Production
Uses
Methyl 4-Oxocyclohexanecarboxylate is an intermediate for preparation of imidazobenzazepine derivatives as dual H1/5-HT2A antagonists for treatment of sleep disorders.
Synthesis
The 4-hydroxy methyl ester (4.147 g; 26.21 mmol) was dissolved in 150 mL DCM, and pyridinium chlorochromate (PCC) (8.476 g; 39.32 mmol) was added. The reaction mixture was allowed to stir at room temperature overnight. The reaction mixture was diluted with ether and decanted. Solvents were removed, and the residue was purified by flash column chromatography using 25 percent EtOAc in a hexane mixture as eluent. The product Methyl 4-ketocyclohexanecarboxylate was obtained as a colorless oil.
Methyl 4-ketocyclohexanecarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 4-ketocyclohexanecarboxylate Suppliers
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- Country
- Canada
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- Advantage
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- Canada
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View Lastest Price from Methyl 4-ketocyclohexanecarboxylate manufacturers
- Product
- Methyl 4-ketocyclohexanecarboxylate 6297-22-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-02