ChemicalBook > CAS DataBase List > L-Ser-OBzl.HCl

L-Ser-OBzl.HCl

Product Name
L-Ser-OBzl.HCl
CAS No.
60022-62-0
Chemical Name
L-Ser-OBzl.HCl
Synonyms
H-SER-OBZL·HCL;H-SER-OBZL HCL;SERINE-OBZL HCL;H-L-Ser-OBzl.HCl;L-SerinebenzylesterHCl;H-L-Ser-Obzl*Hydrochloride;L-SERINE BENZYL ESTER HYDROCHLORIDE;L-SerineBenzylEsterHydrochloride>Benzyl serinate hydrochloride (1:1);benzyl (2S)-2-amino-3-hydroxypropanoate
CBNumber
CB2286886
Molecular Formula
C10H14ClNO3
Formula Weight
231.68
MOL File
60022-62-0.mol
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L-Ser-OBzl.HCl Property

Melting point:
175°C
refractive index 
-12 ° (C=1, H2O)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
form 
powder to crystal
color 
White to Almost white
Water Solubility 
Soluble in water.
InChI
InChI=1/C10H13NO3.ClH/c11-9(6-12)10(13)14-7-8-4-2-1-3-5-8;/h1-5,9,12H,6-7,11H2;1H/t9-;/s3
InChIKey
MGZWCDQAKCHOBX-FVGYRXGTSA-N
SMILES
C(OCC1=CC=CC=C1)(=O)[C@H](CO)N.[H]Cl |&1:10,r|
CAS DataBase Reference
60022-62-0(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29225090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S5633
Product name
L-Serine benzyl ester hydrochloride
Packaging
5g
Price
$195
Updated
2024/03/01
Sigma-Aldrich
Product number
S5633
Product name
L-Serine benzyl ester hydrochloride
Packaging
25g
Price
$398.4
Updated
2024/03/01
TCI Chemical
Product number
S0550
Product name
L-Serine Benzyl Ester Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$113
Updated
2024/03/01
Alfa Aesar
Product number
H28790
Product name
L-Serine benzyl ester hydrochloride, 98%
Packaging
1g
Price
$40.65
Updated
2024/03/01
Alfa Aesar
Product number
H28790
Product name
L-Serine benzyl ester hydrochloride, 98%
Packaging
5g
Price
$116.65
Updated
2024/03/01
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L-Ser-OBzl.HCl Chemical Properties,Usage,Production

Description

L-Serine benzyl ester hydrochloride, also known as L-Serine-Bz-HCl, is a derivative of the amino acid L-Serine. It is a water-soluble, white crystalline powder and is commonly used as a reagent in biochemical and physiological studies. It is a useful raw material that could synthesize mang organic compounds, such as a cyclic sulfamidate which could reacted cleanly with the sodium thiolate salt of a variety of unprotected 1-thio sugars in aqueous buffer to afford the corresponding S-linked amino acid glycoconjugates in good yields after hydrolysis of the N-sulfates[1].

Chemical Properties

Colorless solid

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Preparation

Boc-L-Ser-OBz (2.953 g, 10 mmol) was dissolved in MeOH (21 mL) and was palced in ice bath. Then concentrated hydrochloric acid (4.25 mL) was added dropwise. The ice bath was removed and the reaction mixture was stirred for 3 hours. After that the isopropanol (10 mL) was added and the volatile components were removed under reduced pressure at 55 ℃. The oily residue was coevaporated with isopropanol three times (3x10 mL). L-Serine benzyl ester hydrochloride ( yield=69%) was crystallized from H2O/iPr-OH/acetone mixture.

References

[1] Cohen S, et al. Synthesis of S-linked glycosyl amino acids in aqueous solution with unprotected carbohydrates. Organic Letters, 2001; 3: 405–407.

L-Ser-OBzl.HCl Preparation Products And Raw materials

Raw materials

Preparation Products

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L-Ser-OBzl.HCl Suppliers

HBCChem, Inc.
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View Lastest Price from L-Ser-OBzl.HCl manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
L-Ser-OBzl.HCl 60022-62-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2023-09-27
Henan Fengda Chemical Co., Ltd
Product
L-Ser-OBzl.HCl 60022-62-0
Price
US $8.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-23
Sichuan Jiaying Lai Technology Co.,LTD
Product
H-Ser-OBzl·HCl 60022-62-0
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2019-07-26

60022-62-0, L-Ser-OBzl.HClRelated Search:


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  • H-L-Ser-Obzl*Hydrochloride
  • (S)-2-amino-3-hydroxypropionyloxybenzylhydrochloride
  • Benzyl serinate hydrochloride (1:1)
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  • 60022-62-0
  • Amino Acid Benzyl Esters
  • Amino Acids
  • Amino Acids (C-Protected)
  • Biochemistry