Methyl-DL-serine hydrochloride

Product Name: Methyl-DL-serine hydrochloride
CAS No.: 5619-04-5
Chemical Name: Methyl-DL-serine hydrochloride
Synonyms: Methyl serinate hydrochloride;DL-SERINE METHYL ESTER HYDROCHLORIDE;H-DL-SER-OME HCL;DL-SERINE-OME HCL;Serine Impurity 4;TIMTEC-BB SBB004026;Methyl-DL-serine hydrochloride;DL-Serine methyl hydrochloride;(±)-Serine methyl hydrochloride;Serine, methyl ester, hydrochloride
CBNumber: CB4309417
Molecular Formula: C4H10ClNO3
Formula Weight: 155.58
MOL File: 5619-04-5.mol

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Methyl-DL-serine hydrochloride Property

Melting point:: 134-136 °C(lit.)
Density: 1.37g/cm3 at 20℃
storage temp.: -20°C
solubility: Methanol, Water
form: Solid
color: White to Off-White
Sensitive: Moisture Sensitive
BRN: 6067970
InChI: InChI=1S/C4H9NO3.ClH/c1-8-4(7)3(5)2-6;/h3,6H,2,5H2,1H3;1H
InChIKey: NDBQJIBNNUJNHA-UHFFFAOYSA-N
SMILES: C(N)(CO)C(=O)OC.Cl
LogP: -2 at 20℃ and pH7
Surface tension: 76mN/m at 1g/L and 20℃
CAS DataBase Reference: 5619-04-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25
WGK Germany: 3
HS Code: 29225000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 223131
Product name: DL-Serine methyl ester hydrochloride
Purity: 98%
Packaging: 10g
Price: $60.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: 223131
Product name: DL-Serine methyl ester hydrochloride
Purity: 98%
Packaging: 100g
Price: $386
Updated: 2025/07/31

TCI Chemical

Product number: S0576
Product name: DL-Serine Methyl Ester Hydrochloride
Purity: >98.0%(N)(T)
Packaging: 5g
Price: $19
Updated: 2025/07/31

TCI Chemical

Product number: S0576
Product name: DL-Serine Methyl Ester Hydrochloride
Purity: >98.0%(N)(T)
Packaging: 25g
Price: $30
Updated: 2025/07/31

Usbiological

Product number: 237476
Product name: DL-Serine methyl ester hydrochloride 99+%
Packaging: 5g
Price: $163
Updated: 2021/12/16

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Methyl-DL-serine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

D,L-Serine Methyl Ester Hydrochloride is used as a reactant in the preparation of chicoric acid analogs as HIV-1 integrase inhibitors. Also used in the total synthesis of (-)-Hennoxazole A.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

67-56-1

302-84-1

5619-04-5

100 mL of methanol was added to a 30 mL triple-necked vial placed on a mechanical stirrer and cooled in an ice-water bath. 6.6 ml of dichlorosulfoxide was slowly added dropwise and stirring was continued for 1 hour after completion of the dropwise addition. Subsequently, 6.00 g (57 mmol) of DL-serine was added to the reaction system. The reaction mixture was heated to reflux and the reaction was continued for 18 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The product was dried to give 8.32 g of DL-serine methyl ester hydrochloride in 94.2% yield.

References

[1] Heterocycles, 2012, vol. 86, # 2, p. 1575 - 1582
[2] Patent: CN105777611, 2016, A. Location in patent: Paragraph 0048; 0049
[3] Australian Journal of Chemistry, 1994, vol. 47, # 5, p. 903 - 912
[4] Journal of the Chemical Society. Perkin Transactions 2, 1997, # 3, p. 503 - 507
[5] Journal of the American Chemical Society, 2010, vol. 132, # 7, p. 2274 - 2283

Methyl-DL-serine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl-DL-serine hydrochloride Suppliers

Austria 1 Belgium 1 Canada 1 China 245 Europe 2 Germany 4 India 3 Japan 3 Switzerland 1 United Kingdom 8 United States 24 Global 293

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View Lastest Price from Methyl-DL-serine hydrochloride manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: DL-Ser-OMe·HCl 5619-04-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-04-08

airuikechemical co., ltd.

Product: Methyl-DL-serine hydrochloride 5619-04-5
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.9%
Supply Ability: 200tons
Release date: 2024-04-08

Career Henan Chemical Co

Product: Methyl-DL-serine hydrochloride 5619-04-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: Customized
Release date: 2018-12-21

5619-04-5, Methyl-DL-serine hydrochlorideRelated Search:

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DL-SERINE-OME HCL

H-DL-SER-OME HCL

DL-Serine Methyl ester hydrochloride 98%

TIMTEC-BB SBB004026

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DL -SERINE METHYL ESTER HYDROCHLORIDE CRYSTALLINE

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Methyl-DL-serine hydrochloride

(±)-Serine methyl hydrochloride

DL-Serine methyl hydrochloride

rac-(R*)-2-Amino-3-hydroxypropanoic acid methyl·hydrochloride

DL-Serine methyl ester hydrochloride,99%

DL-SerineMethylEsterHydrochloride&gt

Serine Impurity 4

Methyl serinate hydrochloride

<sc>DL</sc>-Serine methyl ester hydrochloride

Methyl 2-amino-3-hydroxy-propanoate HCl

5619-04-5

5619-4-5

6519-04-5

C4H9NO3xHCl

HOCH2CHNH2CO2CH3HCl

C4H9NO3HCl

C4H19NO3HCl

C4H9NO3ClH

Peptide Synthesis

I - Z

Modified Amino Acids

Serine

Specialty Synthesis

BioChemical

Amino Acid Derivatives

Amino Acids and Peptides

Biochemicals and Reagents

Serine [Ser, S]

Amino ACIDS SERIES

Amino Acid Methyl Esters

Amino Acids

Amino Acids (C-Protected)

Biochemistry

Amino Acids

I - ZPeptide Synthesis

Modified Amino Acids

Amino Acid Derivatives

Peptide Synthesis

Serine

Amino Acids & Derivatives