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OCHRATOXIN B

Product Name
OCHRATOXIN B
CAS No.
4825-86-9
Chemical Name
OCHRATOXIN B
Synonyms
OCHRATOXIN B;(r)-carbonyl);Ochratoxin B(OTB);ochratoxin b solution;Ochratoxin B in Methanol;Ochratoxin B 10ug/ml in ACN;Ochratoxin B in acetonitrile;Ochratoxin B 10.0 μg/ml Acetonitrile;ochratoxin B from aspergillus ochraceus;U-[13C20]- Ochratoxin B in Acetonitrile
CBNumber
CB2297543
Molecular Formula
C20H19NO6
Formula Weight
369.37
MOL File
4825-86-9.mol
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OCHRATOXIN B Property

Melting point:
221° (van der Merwe)
alpha 
D -35° (c = 0.15 in ethanol)
Boiling point:
632.4±55.0 °C(Predicted)
Density 
1.361±0.06 g/cm3(Predicted)
Flash point:
-11 °C
storage temp. 
2-8°C
solubility 
DMF: 10 mg/ml; DMSO: 15 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.50 mg/ml
form 
A crystalline solid
pka
3.40±0.10(Predicted)
color 
White to off-white
EPA Substance Registry System
L-Phenylalanine, N-[[(3R)-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]- (4825-86-9)
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Safety

Hazard Codes 
Xn,T,F
Risk Statements 
22-36/37/38-65-48/23/24/25-36/38-11-46-45-36-20/21/22
Safety Statements 
26-36-45-16-53-36/37-62
RIDADR 
UN 3462 6.1/PG 3
WGK Germany 
3
RTECS 
AY6825000
HazardClass 
6.1(a)
PackingGroup 
I
HS Code 
39229000
Hazardous Substances Data
4825-86-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H302Harmful if swallowed

H312Harmful in contact with skin

H319Causes serious eye irritation

H332Harmful if inhaled

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
32411
Product name
Ochratoxin B solution
Purity
10?μg/mL in acetonitrile, analytical standard
Packaging
1ML
Price
$515
Updated
2024/03/01
Cayman Chemical
Product number
16167
Product name
Ochratoxin B
Purity
≥98%
Packaging
500μg
Price
$111
Updated
2024/03/01
Cayman Chemical
Product number
16167
Product name
Ochratoxin B
Purity
≥98%
Packaging
1mg
Price
$210
Updated
2024/03/01
Cayman Chemical
Product number
16167
Product name
Ochratoxin B
Purity
≥98%
Packaging
5mg
Price
$601
Updated
2024/03/01
Usbiological
Product number
O5305-04
Product name
Ochratoxin B
Packaging
1mg
Price
$426
Updated
2021/12/16
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OCHRATOXIN B Chemical Properties,Usage,Production

Description

Ochratoxins are mycotoxins produced by Aspergillus and Penicillium species of fungi that contaminate foods. Ochratoxin A (OTA, ) is a chlorinated form with toxicity that targets the kidneys, causing nephropathy and renal adenomas. OTB is a non-chlorinated analog of OTA that has cytotoxic effects on kidney and liver cells in vitro but only minor effects in vivo, due to its rapid metabolism and excretion. OTB inhibits cell proliferation of human liver HepG2 cells at doses as low as 1 μg/ml but lacks the genotoxic activity of OTA, even at higher concentrations.

Uses

Ochratoxin B is the non-chlorinated analogue of the much more extensively studied ochratoxin A. It is co-produced by the same species of Aspergillus and Penicillium that are associated with food spoilage. Ochratoxin B has received little focused investigation and its mode of action and potential hazards have been inferred from ochratoxin A.

Uses

Ochratoxins are toxic metabolites from Aspergillus orchraceus.

Definition

ChEBI: Ochratoxin B is a phenylalanine derivative resulting from the formal condensation of the amino group of L-phenylalanine with the carboxy group of (3R)-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-2-benzopyran-7-carboxylic acid. Ochratoxin B differs from the more naturally abundant ochratoxin A in the absence of the dihydroisocoumarin chlorine atom. It has cytotoxic effects on kidney and liver cells in vitro but only minor effects in vivo, due to its rapid metabolism and excretion. It inhibits cell proliferation of human liver HepG2 cells at doses as low as 1 mug/ ml but lacks the genotoxic activity of ochratoxin A, even at higher concentrations. It has a role as an Aspergillus metabolite, a Penicillium metabolite, a mycotoxin and a calcium channel blocker. It is a phenylalanine derivative, a N-acyl-L-phenylalanine, a member of isochromanes and a monocarboxylic acid. It is a conjugate acid of an ochratoxin B(1-).

General Description

Crystals that exhibit blue fluorescence.

Reactivity Profile

OCHRATOXIN B is incompatible with strong oxidizing agents, strong acids and strong bases. OCHRATOXIN B is a carboxylic acid derivative. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt.

Fire Hazard

Flash point data for OCHRATOXIN B are not available. OCHRATOXIN B is probably combustible.

OCHRATOXIN B Preparation Products And Raw materials

Raw materials

Preparation Products

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OCHRATOXIN B Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4511
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Qingdao IniKem BioPharmaTech Co.,Ltd
Tel
0532-58268780
Fax
-
Email
sales@inikem.com
Country
China
ProdList
282
Advantage
55
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
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View Lastest Price from OCHRATOXIN B manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Ochratoxin B 4825-86-9
Price
US $1.00-22.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000KG
Release date
2024-07-29

4825-86-9, OCHRATOXIN BRelated Search:


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