OCHRATOXIN B
- Product Name
- OCHRATOXIN B
- CAS No.
- 4825-86-9
- Chemical Name
- OCHRATOXIN B
- Synonyms
- OCHRATOXIN B;(r)-carbonyl);Ochratoxin B(OTB);ochratoxin b solution;Ochratoxin B 10ug/ml in ACN;ochratoxin B from aspergillus ochraceus;Ochratoxin B, 99%, from Aspergillus ochraceus;Ochratoxin B Solution (10μg/ml in Acetonitrile Solution);ochratoxin b from aspergillus ochraceus (aspergillus oryzae);N-[(8-Hydroxy-3-Methyl-1-oxo-7-isochroManyl)carbonyl]-3-phenyl-L- alanine
- CBNumber
- CB2297543
- Molecular Formula
- C20H19NO6
- Formula Weight
- 369.37
- MOL File
- 4825-86-9.mol
OCHRATOXIN B Property
- Melting point:
- 221° (van der Merwe)
- alpha
- D -35° (c = 0.15 in ethanol)
- Boiling point:
- 632.4±55.0 °C(Predicted)
- Density
- 1.361±0.06 g/cm3(Predicted)
- Flash point:
- -11 °C
- storage temp.
- 2-8°C
- solubility
- DMF: 10 mg/ml; DMSO: 15 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.50 mg/ml
- form
- A crystalline solid
- pka
- 3.40±0.10(Predicted)
- EPA Substance Registry System
- L-Phenylalanine, N-[[(3R)-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]- (4825-86-9)
Safety
- Hazard Codes
- Xn,T,F
- Risk Statements
- 22-36/37/38-65-48/23/24/25-36/38-11-46-45-36-20/21/22
- Safety Statements
- 26-36-45-16-53-36/37-62
- RIDADR
- UN 3462 6.1/PG 3
- WGK Germany
- 3
- RTECS
- AY6825000
- HazardClass
- 6.1(a)
- PackingGroup
- I
- HS Code
- 39229000
- Hazardous Substances Data
- 4825-86-9(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H332Harmful if inhaled
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 32411
- Product name
- Ochratoxin B solution
- Purity
- 10?μg/mL in acetonitrile, analytical standard
- Packaging
- 1ML
- Price
- $515
- Updated
- 2024/03/01
- Product number
- 16167
- Product name
- Ochratoxin B
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $111
- Updated
- 2024/03/01
- Product number
- 16167
- Product name
- Ochratoxin B
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $210
- Updated
- 2024/03/01
- Product number
- 16167
- Product name
- Ochratoxin B
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $601
- Updated
- 2024/03/01
- Product number
- O5305-04
- Product name
- Ochratoxin B
- Packaging
- 1mg
- Price
- $426
- Updated
- 2021/12/16
OCHRATOXIN B Chemical Properties,Usage,Production
Description
Ochratoxins are mycotoxins produced by Aspergillus and Penicillium species of fungi that contaminate foods. Ochratoxin A (OTA, ) is a chlorinated form with toxicity that targets the kidneys, causing nephropathy and renal adenomas. OTB is a non-
Uses
Ochratoxin B is the non-chlorinated analogue of the much more extensively studied ochratoxin A. It is co-produced by the same species of Aspergillus and Penicillium that are associated with food spoilage. Ochratoxin B has received little focused investigation and its mode of action and potential hazards have been inferred from ochratoxin A.
Uses
Ochratoxins are toxic metabolites from Aspergillus orchraceus.
Definition
ChEBI: Ochratoxin B is a phenylalanine derivative resulting from the formal condensation of the amino group of L-phenylalanine with the carboxy group of (3R)-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-2-benzopyran-7-carboxylic acid. Ochratoxin B differs from the more naturally abundant ochratoxin A in the absence of the dihydroisocoumarin chlorine atom. It has cytotoxic effects on kidney and liver cells in vitro but only minor effects in vivo, due to its rapid metabolism and excretion. It inhibits cell proliferation of human liver HepG2 cells at doses as low as 1 mug/ ml but lacks the genotoxic activity of ochratoxin A, even at higher concentrations. It has a role as an Aspergillus metabolite, a Penicillium metabolite, a mycotoxin and a calcium channel blocker. It is a phenylalanine derivative, a N-acyl-L-phenylalanine, a member of isochromanes and a monocarboxylic acid. It is a conjugate acid of an ochratoxin B(1-).
General Description
Crystals that exhibit blue fluorescence.
Reactivity Profile
OCHRATOXIN B is incompatible with strong oxidizing agents, strong acids and strong bases. OCHRATOXIN B is a carboxylic acid derivative. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt.
Fire Hazard
Flash point data for OCHRATOXIN B are not available. OCHRATOXIN B is probably combustible.
OCHRATOXIN B Preparation Products And Raw materials
Raw materials
Preparation Products
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