ChemicalBook > CAS DataBase List > 1-N-PHENYL-PIPERIDIN-4-ONE

1-N-PHENYL-PIPERIDIN-4-ONE

Product Name
1-N-PHENYL-PIPERIDIN-4-ONE
CAS No.
19125-34-9
Chemical Name
1-N-PHENYL-PIPERIDIN-4-ONE
Synonyms
N-Phenyl-4-piperidone;1-Phenyl-4-piperidone;N-phenylpiperidin-4-one;4-Piperidinone,1-phenyl-;1-PHENYLPIPERIDIN-4-ONE;1-N-PHENYL-PIPERIDIN-4-ONE;1-phenylpiperidin-4-one(SALTDATA: FREE)
CBNumber
CB2301048
Molecular Formula
C11H13NO
Formula Weight
175.23
MOL File
19125-34-9.mol
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1-N-PHENYL-PIPERIDIN-4-ONE Property

Melting point:
36.5-37.2℃
storage temp. 
Sealed in dry,Room Temperature
Appearance
Light yellow to brown Solid
InChI
InChI=1S/C11H13NO/c13-11-6-8-12(9-7-11)10-4-2-1-3-5-10/h1-5H,6-9H2
InChIKey
VPGLFNOKHAIGEC-UHFFFAOYSA-N
SMILES
N1(C2=CC=CC=C2)CCC(=O)CC1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
P336245
Product name
1-Phenylpiperidin-4-one
Packaging
100mg
Price
$120
Updated
2021/12/16
TRC
Product number
P336245
Product name
1-Phenylpiperidin-4-one
Packaging
5G
Price
$715
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0018385
Product name
1-N-PHENYL-PIPERIDIN-4-ONE
Purity
95.00%
Packaging
1G
Price
$750.68
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
66704
Product name
1-Phenylpiperidin-4-one
Packaging
100mg
Price
$610
Updated
2021/12/16
Matrix Scientific
Product number
131962
Product name
1-Phenylpiperidin-4-one
Purity
97%
Packaging
5g
Price
$874
Updated
2021/12/16
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1-N-PHENYL-PIPERIDIN-4-ONE Chemical Properties,Usage,Production

Uses

1-Phenylpiperidin-4-one is a reagent used in the preparation of isoteric N-arylpiperazine as dihydropyridine NPY1 receptor antagonists.

Synthesis

198649-62-6

19125-34-9

The compound (CAS: 198649-62-6) was dissolved in ethanol (60 mL), 2M hydrochloric acid (15 mL) was added and the reaction was heated to reflux for 5 hours. Upon completion of the reaction, the reaction solution was neutralized by adding aqueous sodium bicarbonate to the reaction solution, followed by extraction of the organic phase with ethyl acetate. The organic phase was concentrated under reduced pressure and the resulting residue was purified by silica gel column chromatography (Moritex Corporation, eluent: hexane/ethyl acetate=5/1). Fractions with an Rf value of 0.40 were collected and confirmed by thin layer chromatography and concentrated under reduced pressure to give 1-N-phenyl-1-piperidin-4-one (6.1 g, 35 mmol) as a colorless oil (quantitative yield). Mass spectrum (MS) m/z: 176 (M + H)+.

References

[1] Patent: US2011/112103, 2011, A1. Location in patent: Page/Page column 23
[2] Patent: WO2010/81851, 2010, A1. Location in patent: Page/Page column 15; 16
[3] Patent: WO2013/6408, 2013, A1. Location in patent: Page/Page column 63
[4] Tetrahedron Letters, 2007, vol. 48, # 23, p. 4097 - 4099
[5] Patent: CN105985355, 2016, A. Location in patent: Paragraph 0639; 0640; 0641; 0642

1-N-PHENYL-PIPERIDIN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-N-PHENYL-PIPERIDIN-4-ONE Suppliers

China 67 India 7 Ukraine 1 United Kingdom 1 United States 12 Global 88
UkrOrgSynthesis Ltd.
Tel
--
Fax
--
Email
y.barysheva@ukrorgsynth.com
Country
Ukraine
ProdList
6230
Advantage
38
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View Lastest Price from 1-N-PHENYL-PIPERIDIN-4-ONE manufacturers

Career Henan Chemical Co
Product
1-N-PHENYL-PIPERIDIN-4-ONE 19125-34-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1lg; 2kg; 5kg; 10kg; 100kg
Release date
2019-08-31

19125-34-9, 1-N-PHENYL-PIPERIDIN-4-ONERelated Search:

TPCK N-Cbz-Nortropinone 1-BOC-3-PHENYL-PIPERIDIN-4-ONE 1-BOC-2-PHENYL-PIPERIDIN-4-ONE,1-N-BOC-2-PHENYL-PIPERIDIN-4-ONE 1-(4-CHLORO-PHENYL)-PIPERIDIN-4-ONE CHEMBRDG-BB 4000320 1-(3,4-DIFLUORO-PHENYL)-PIPERIDIN-4-ONE 1-PHENYLPIPERIDIN-4-ONE HYDROCHLORIDE CHEMBRDG-BB 4000321 1-(2-FLUORO-PHENYL)-PIPERIDIN-4-ONE 1-(3,5-DIMETHYL-PHENYL)-PIPERIDIN-4-ONE 1-[2,6-DINITRO-4-(TRIFLUOROMETHYL)PHENYL]TETRAHYDRO-4(1H)-PYRIDINONE 1-(3-CHLORO-PHENYL)-PIPERIDIN-4-ONE 1-(4-FLUORO-PHENYL)-PIPERIDIN-4-ONE 1-(3-METHYLPHENYL)PIPERIDIN-4-ONE 1-(2-nitrophenyl)piperidin-4-one 1-(4-methylphenyl)piperidin-4-one 1-(1,3-BENZODIOXOL-5-YL)PIPERIDIN-4-ONE

  • 1-Phenyl-4-piperidone
  • N-Phenyl-4-piperidone
  • 4-Piperidinone,1-phenyl-
  • 1-N-PHENYL-PIPERIDIN-4-ONE
  • 1-PHENYLPIPERIDIN-4-ONE
  • 1-phenylpiperidin-4-one(SALTDATA: FREE)
  • N-phenylpiperidin-4-one
  • 19125-34-9
  • CHIRAL CHEMICALS