ChemicalBook > CAS DataBase List > 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide

2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide

Product Name
2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
CAS No.
1375466-18-4
Chemical Name
2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
Synonyms
ACY-775;ACY-77;CS-2821;ACY-775 (ACY 775;ACY-775; ACY 775; ACY775.;ACY-775,Histone deacetylases,inhibit,Inhibitor,ACY 775,HDAC,ACY775;5-Pyrimidinecarboxamide, 2-[[1-(3-fluorophenyl)cyclohexyl]amino]-N-hydroxy-;2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
CBNumber
CB23042717
Molecular Formula
C17H19FN4O2
Formula Weight
330.36
MOL File
1375466-18-4.mol
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2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide Property

Density 
1.342±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
DMSO:35.33(Max Conc. mg/mL);106.94(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);60.54(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.61(Max Conc. mM)
Ethanol:34.5(Max Conc. mg/mL);104.43(Max Conc. mM)
form 
A solid
pka
7.74±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A305320
Product name
ACY-775
Packaging
10mg
Price
$235
Updated
2021/12/16
Adipogen Life Sciences
Product number
AG-CR1-3903-M005
Product name
ACY-775
Purity
≥95%(HPLC)
Packaging
5mg
Price
$490
Updated
2021/12/16
ChemScene
Product number
CS-7689
Product name
ACY-775
Purity
99.83%
Packaging
50mg
Price
$588
Updated
2021/12/16
ChemScene
Product number
CS-7689
Product name
ACY-775
Purity
99.83%
Packaging
2mg
Price
$108
Updated
2021/12/16
ChemScene
Product number
CS-7689
Product name
ACY-775
Purity
99.83%
Packaging
5mg
Price
$144
Updated
2021/12/16
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2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide Chemical Properties,Usage,Production

Uses

ACY-775 is a novel histone deacetylase 6-selective (HDAC6) inhibitor with antidepressant and pro-cognitive properties. ACY-775 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs.

2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide Suppliers

China 42 United States 6 Global 48
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6393
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58

1375466-18-4, 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamideRelated Search:


  • ACY-775
  • 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
  • ACY-775; ACY 775; ACY775.
  • CS-2821
  • ACY-775 (ACY 775
  • ACY-77
  • 5-Pyrimidinecarboxamide, 2-[[1-(3-fluorophenyl)cyclohexyl]amino]-N-hydroxy-
  • ACY-775,Histone deacetylases,inhibit,Inhibitor,ACY 775,HDAC,ACY775
  • 1375466-18-4