ChemicalBook > CAS DataBase List > 5-Hydroxymethylpyrrolidin-2-one

5-Hydroxymethylpyrrolidin-2-one

Product Name
5-Hydroxymethylpyrrolidin-2-one
CAS No.
66673-40-3
Chemical Name
5-Hydroxymethylpyrrolidin-2-one
Synonyms
D-PYROGLUTAMINOL;D-Pyr-ol;H-D-Pyr-ol;(-)-D-PYROGLUTAMOL;(R)-(-)-5-(HydroxymethyL;5-Hydroxymethylpyrrolidin-2-one;5-(Hydroxymethyl)-2-pyrrolidinone;(R)-(-)-2-PYRROLIDONE-5-YL-METHANOL;(R)-5-HYDROXYMETHYL-PYRROLIDIN-2-ONE;(R)-5-(HYDROXYMETHYL)-2-PYRROLIDINONE
CBNumber
CB2304847
Molecular Formula
C5H9NO2
Formula Weight
115.13
MOL File
66673-40-3.mol
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5-Hydroxymethylpyrrolidin-2-one Property

Melting point:
83-85 °C(lit.)
Boiling point:
147-149 °C0.06 mm Hg(lit.)
Density 
1.1808 (rough estimate)
refractive index 
-31 ° (C=5, EtOH)
Flash point:
147-149°C/0.06m
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform, Dimethylformamide, Water
form 
Crystalline Powder or Flakes
pka
14.35±0.10(Predicted)
color 
White to yellow
optical activity
[α]20/D 31°, c = 5 in ethanol
BRN 
5728422
CAS DataBase Reference
66673-40-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
3-10
HS Code 
29337900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
366358
Product name
(R)-(?)-5-(Hydroxymethyl)-2-pyrrolidinone
Purity
99%
Packaging
1g
Price
$45.1
Updated
2023/06/20
Sigma-Aldrich
Product number
366358
Product name
(R)-(?)-5-(Hydroxymethyl)-2-pyrrolidinone
Purity
99%
Packaging
5g
Price
$177
Updated
2023/06/20
TCI Chemical
Product number
H1241
Product name
(R)-5-(Hydroxymethyl)-2-pyrrolidinone
Purity
>98.0%(GC)(N)
Packaging
1g
Price
$64
Updated
2024/03/01
TCI Chemical
Product number
H1241
Product name
(R)-5-(Hydroxymethyl)-2-pyrrolidinone
Purity
>98.0%(GC)(N)
Packaging
5g
Price
$176
Updated
2024/03/01
Alfa Aesar
Product number
L18358
Product name
(R)-(-)-5-(Hydroxymethyl)-2-pyrrolidinone, 99%
Packaging
1g
Price
$69.65
Updated
2024/03/01
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5-Hydroxymethylpyrrolidin-2-one Chemical Properties,Usage,Production

Chemical Properties

(R)-5-(Hydroxymethyl)-2-pyrrolidinone is White Powder

Uses

(R)-5-(Hydroxymethyl)-2-pyrrolidinone is a 2-pyrrolidone derivative for therapeutic use as prostanoid receptor agonist.

Uses

Serves as a building block in the synthesis of diphthamide.

5-Hydroxymethylpyrrolidin-2-one Preparation Products And Raw materials

Raw materials

Ethanol L-Glutamic acid Sodium borohydride D(-)-Glutamic acid Tetrahydrofuran Ethyl acetate Hydrochloric acid Acetic acid Lithium chloride

Preparation Products

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View Lastest Price from 5-Hydroxymethylpyrrolidin-2-one manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
D-Pyr-ol 66673-40-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-01-17
Henan Fengda Chemical Co., Ltd
Product
(R)-(-)-5-(Hydroxymethyl)-2-pyrrolidinone 66673-40-3
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-31
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Hydroxymethylpyrrolidin-2-one 66673-40-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

66673-40-3, 5-Hydroxymethylpyrrolidin-2-oneRelated Search:

5-Hydroxymethylpyrrolidin-2-one 2-Pyrrolidone-5-carboxylic acid sodium salt Ethyl L-pyroglutamate DIRHODIUM (II) TETRAKIS(METHYL 2-PYRROLIDONE-5(R)-CARBOXYLATE)ACETONITRILE/2-PROPANOL COMPLEX Cyclopentene oxide L-PYROGLUTAMIC ACID PENTACHLOROPHENYL ESTER CLASTO-LACTACYSTIN EQUISETIN Ethyl D-(-)-pyroglutamate DL-Pyroglutamic acid D-Pyroglutamic acid L-Arginine-L-pyroglutamate Z-PYR-OH Z-D-PYR-OH CALCIUM PIDOLATE (S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone p-toluenesulfonate L-Pyroglutaminol ALPHA-PYRIDOIN

  • D-PYROGLUTAMINOL
  • (-)-D-PYROGLUTAMOL
  • (R)-5-HYDROXYMETHYL-PYRROLIDIN-2-ONE
  • (R)-(-)-5-(HYDROXYMETHYL)-2-PYRROLIDINONE
  • (R)-5-(HYDROXYMETHYL)-2-PYRROLIDINONE
  • (R)-(-)-5-(HYDROXYMETHYL)-2-PYRROLIDONE
  • (R)-(-)-2-PYRROLIDONE-5-YL-METHANOL
  • 5-(Hydroxymethyl)-2-pyrrolidinone
  • 5-Hydroxymethylpyrrolidin-2-one
  • H-D-Pyr-ol
  • (R)-(-)-5-Hydroxymethyl-2-pyrrolidinone,98%
  • (5R)-5-(Hydroxymethyl)-2-pyrrolidinone
  • (5R)-5-(Hydroxymethyl)pyrrolidin-2-one
  • (2)(R)-5-(HydroxyMethyl)-2-pyrrolidinone
  • (<i>R</i>)-5-(Hydroxymethyl)-2-pyrrolidinone
  • (R)-5-(Hydroxymethyl)-2-pyrrolidinone,99%e.e.
  • (R)-5-(Hydroxymethyl)-2-pyrrolidinone&gt
  • (R)-(-)-5-(HydroxymethyL
  • 2-Pyrrolidinone, 5-(hydroxymethyl)-, (5R)-
  • 5-Hydroxymethylpyrrolidin-2-one USP/EP/BP
  • D-Pyr-ol
  • 66673-40-3
  • Heterocyclic Building Blocks
  • Pyrrolidines
  • ALCOHOL
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Heterocycles
  • pharmacetical
  • Amino Acids 13C, 2H, 15N
  • Amides (Chiral)
  • Chiral Building Blocks
  • Synthetic Organic Chemistry
  • Amino Acids & Derivatives
  • Chiral Reagents