ChemicalBook > CAS DataBase List > 2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE

2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE

Product Name
2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE
CAS No.
73604-31-6
Chemical Name
2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE
Synonyms
3-Hydroxybenzylamine,98%;Phenol, 3-(aminomethyl)-;3-Hydroxybenzylamine, >=97%;3-Hydroxybenzenemethanamine;[(3-Hydroxyphenyl)methyl]amine;Metaraminol Bitartrate Impurity 31;2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE;3-HYDROXYBENZYLAMINE[3-(AMINOMETHYL)PHENOL];3-Hydroxybenzylamine, (3-Hydroxyphenyl)methylamine
CBNumber
CB2305248
Molecular Formula
C7H9NO
Formula Weight
123.15
MOL File
73604-31-6.mol
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2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE Property

Melting point:
174-176
Boiling point:
264.7±15.0 °C(Predicted)
Density 
1.141±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
9.86±0.10(Predicted)
form 
powder
color 
Faint beige to faint brown
Water Solubility 
Soluble in water and ethanol.
Sensitive 
Air Sensitive
InChI
InChI=1S/C7H9NO/c8-5-6-2-1-3-7(9)4-6/h1-4,9H,5,8H2
InChIKey
JNZYADHPGVZMQK-UHFFFAOYSA-N
SMILES
C1(O)=CC=CC(CN)=C1
CAS DataBase Reference
73604-31-6
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Safety

Hazard Codes 
Xi
RIDADR 
UN3259
Hazard Note 
Irritant
HazardClass 
8
HS Code 
2922290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A3559
Product name
3-(Aminomethyl)phenol
Packaging
1G
Price
$91
Updated
2025/07/31
TCI Chemical
Product number
A3559
Product name
3-(Aminomethyl)phenol
Packaging
5G
Price
$243
Updated
2025/07/31
TRC
Product number
H809730
Product name
3-Hydroxybenzylamine
Packaging
250mg
Price
$160
Updated
2021/12/16
Apolloscientific
Product number
OR14753
Product name
3-(Aminomethyl)phenol
Packaging
5g
Price
$221
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA70624
Product name
3-(Aminomethyl)phenol
Packaging
5G
Price
$250
Updated
2021/12/16
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2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

3-Hydroxybenzylamine is used as pharmaceutical intermediate.

Definition

ChEBI: 3-(aminomethyl)phenol is an aromatic amine.

Synthesis

873-62-1

73604-31-6

Under nitrogen protection, 10.0 g of 3-hydroxybenzonitrile (Compound 1) and 1 g of Ruanne nickel were added to a 500 mL three-necked flask and 200 mL of methanol was injected to displace the hydrogen atmosphere. The reaction system was stirred overnight at room temperature. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad to remove the catalyst. The filtrate was concentrated under reduced pressure to give 10 g of 3-(aminomethyl)phenol (compound 2) as a white solid in 97% yield. High performance liquid chromatography (HPLC) analysis showed the product to be 97% pure and could be used in subsequent reactions without further purification.

References

[1] Patent: CN107266341, 2017, A. Location in patent: Paragraph 0045-0048
[2] European Journal of Medicinal Chemistry, 2018, vol. 150, p. 757 - 770
[3] Patent: EP696593, 1996, A2
[4] Journal of the Chemical Society - Series Chemical Communications, 1986, vol. No. 2, p. 158 - 160

2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE Suppliers

Block Chemical Technology (Shanghai) Co., LTD
Tel
021-20432219 13918097649
Fax
QQ79021576
Email
li_jinfei@acblock-lab.com
Country
China
ProdList
9673
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58
Shandong Fande Pharmaceutical Technology Co., Ltd.
Tel
0531-00000000 15552883993
Email
3180453864@qq.com
Country
China
ProdList
96
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58
SHANGHAI XINZI BioScience, Inc
Tel
021-59865198 18633820375
Email
lzy1974@163.com
Country
China
ProdList
4
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58
Shandong Yunxing Pharmaceutical R&D Co., Ltd
Tel
13153019312
Email
3977218233@qq.com
Country
China
ProdList
39
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58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
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China
ProdList
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
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56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
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View Lastest Price from 2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE 73604-31-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-08-20

73604-31-6, 2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDERelated Search:


  • 2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE
  • 3-HYDROXYBENZYLAMINE[3-(AMINOMETHYL)PHENOL]
  • 3-Hydroxybenzylamine, (3-Hydroxyphenyl)methylamine
  • [(3-Hydroxyphenyl)methyl]amine
  • 3-Hydroxybenzenemethanamine
  • 3-Hydroxybenzylamine, >=97%
  • Phenol, 3-(aminomethyl)-
  • Metaraminol Bitartrate Impurity 31
  • 3-Hydroxybenzylamine,98%
  • 73604-31-6
  • Anilines, Aromatic Amines and Nitro Compounds