2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE
- Product Name
- 2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE
- CAS No.
- 73604-31-6
- Chemical Name
- 2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE
- Synonyms
- 3-Hydroxybenzylamine,98%;Phenol, 3-(aminomethyl)-;3-Hydroxybenzylamine, >=97%;3-Hydroxybenzenemethanamine;[(3-Hydroxyphenyl)methyl]amine;Metaraminol Bitartrate Impurity 31;2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE;3-HYDROXYBENZYLAMINE[3-(AMINOMETHYL)PHENOL];3-Hydroxybenzylamine, (3-Hydroxyphenyl)methylamine
- CBNumber
- CB2305248
- Molecular Formula
- C7H9NO
- Formula Weight
- 123.15
- MOL File
- 73604-31-6.mol
2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE Property
- Melting point:
- 174-176
- Boiling point:
- 264.7±15.0 °C(Predicted)
- Density
- 1.141±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 9.86±0.10(Predicted)
- form
- powder
- color
- Faint beige to faint brown
- Water Solubility
- Soluble in water and ethanol.
- Sensitive
- Air Sensitive
- InChI
- InChI=1S/C7H9NO/c8-5-6-2-1-3-7(9)4-6/h1-4,9H,5,8H2
- InChIKey
- JNZYADHPGVZMQK-UHFFFAOYSA-N
- SMILES
- C1(O)=CC=CC(CN)=C1
- CAS DataBase Reference
- 73604-31-6
Safety
- Hazard Codes
- Xi
- RIDADR
- UN3259
- Hazard Note
- Irritant
- HazardClass
- 8
- HS Code
- 2922290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A3559
- Product name
- 3-(Aminomethyl)phenol
- Packaging
- 1G
- Price
- $91
- Updated
- 2025/07/31
- Product number
- A3559
- Product name
- 3-(Aminomethyl)phenol
- Packaging
- 5G
- Price
- $243
- Updated
- 2025/07/31
- Product number
- H809730
- Product name
- 3-Hydroxybenzylamine
- Packaging
- 250mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- OR14753
- Product name
- 3-(Aminomethyl)phenol
- Packaging
- 5g
- Price
- $221
- Updated
- 2021/12/16
- Product number
- FA70624
- Product name
- 3-(Aminomethyl)phenol
- Packaging
- 5G
- Price
- $250
- Updated
- 2021/12/16
2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
3-Hydroxybenzylamine is used as pharmaceutical intermediate.
Definition
ChEBI: 3-(aminomethyl)phenol is an aromatic amine.
Synthesis
873-62-1
73604-31-6
Under nitrogen protection, 10.0 g of 3-hydroxybenzonitrile (Compound 1) and 1 g of Ruanne nickel were added to a 500 mL three-necked flask and 200 mL of methanol was injected to displace the hydrogen atmosphere. The reaction system was stirred overnight at room temperature. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad to remove the catalyst. The filtrate was concentrated under reduced pressure to give 10 g of 3-(aminomethyl)phenol (compound 2) as a white solid in 97% yield. High performance liquid chromatography (HPLC) analysis showed the product to be 97% pure and could be used in subsequent reactions without further purification.
References
[1] Patent: CN107266341, 2017, A. Location in patent: Paragraph 0045-0048
[2] European Journal of Medicinal Chemistry, 2018, vol. 150, p. 757 - 770
[3] Patent: EP696593, 1996, A2
[4] Journal of the Chemical Society - Series Chemical Communications, 1986, vol. No. 2, p. 158 - 160
2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE manufacturers
- Product
- 2-PHENOXY-N-METHYLETHYLAMINE HYDROCHLORIDE 73604-31-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-08-20