VALNEMULIN HYDROCHLORIDE

Product Name: VALNEMULIN HYDROCHLORIDE
CAS No.: 133868-46-9
Chemical Name: VALNEMULIN HYDROCHLORIDE
Synonyms: econor;Etodoiac;VALNEMULIN HCL;ValneMulin hyd;UNII-W1GDP58BNQ;VALNEMULIN HYDROCH;Valnemulin Hydrochlorid;Vonimorin hydrochloride;Valnemulin Hydrocloride;VALNEMULIN HYDROCHLORIDE
CBNumber: CB2305682
Molecular Formula: C31H53ClN2O5S
Formula Weight: 601.28
MOL File: 133868-46-9.mol

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VALNEMULIN HYDROCHLORIDE Property

Melting point:: 140-143?C
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
Merck: 14,9911
InChIKey: MFBPRQKHDIVLOJ-AFFLPQGKSA-N
SMILES: C[C@H]1[C@@H]([C@](C[C@@H](OC(=O)CSC(C)(C)CNC(=O)[C@H](N)C(C)C)C2([C@H](C)CCC31CCC(=O)[C@]32[H])C)(C)C=C)O.Cl |&1:1,2,3,5,18,24,33,r|

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Safety

WGK Germany: 3
HS Code: 2941.90.5000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H335May cause respiratory irritation

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000585
Product name: Valnemulin for peak identification
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 20 mg
Price: $152
Updated: 2025/07/31

Sigma-Aldrich

Product number: Y0000584
Product name: Valnemulin hydrochloride
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 10 mg
Price: $156
Updated: 2025/07/31

Sigma-Aldrich

Product number: SBR00094
Product name: Valnemulin hydrochloride
Purity: ≥96% (HPLC), powder
Packaging: 1 unit
Price: $44.79
Updated: 2025/07/31

Sigma-Aldrich

Product number: 32375
Product name: Valnemulin hydrochloride
Purity: VETRANAL
Packaging: 25mg
Price: $340
Updated: 2025/07/31

Sigma-Aldrich

Product number: Y0000584
Product name: Valnemulin hydrochloride
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000584
Price: $153
Updated: 2024/03/01

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VALNEMULIN HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Uses

Hydrochloride salt Valnemulin, semisynthetic antibiotic; derivative of pleuromutilin. Antibacterial.

Uses

Valnemulin hydrochloride is the salt prepared from valnemulin taking advantage of the basic amino group which protonates and readily forms the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Valnemulin is a broad spectrum antibiotic used to control gastrointestinal infections in animals, and shows no cross resistance to other antibiotic classes. Like all the pleuromutilins, valnemulin inhibits protein synthesis by binding to domain V of 23S RNA.

Uses

Valnemulin Hydrochloride is a semisynthetic antibiotic; derivative of pleuromutilin. Antibacterial.

Biological Activity

Valnemulin Hydrochloride inhibits bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome. More specifically, it binds to the peptidyl transferase center of the ribosome and interferes with the transfer of amino acids to growing polypeptide chains, leading to the inhibition of protein synthesis and bacterial death.

in vivo

Valnemulin hydrochloride (10 mg/kg in non-salt form; Oral administration; 10 days) has a control effect in experimental infection of calves with Mycoplasma bovis, and can effectively eliminate Mycobacterium bovis in the lungs ^[1].
Valnemulin hydrochloride (20-35 ppm; Feed administration; 21 days) effectively reduces the mortality of epidemic rabbit enteropathy, and has no adverse effect on the growth performance of rabbits ^[2].

Animal Model:	Mycoplasma bovis infection treated male calves aged 10-35 days^[1]
Dosage:	10 mg/kg in non-salt form
Administration:	Oral administration (p.o.); 10 days
Result:	Resulted in a rapid diminution of clinical signs, restoration of appetite and reversal of weight loss. Effectively reduced the isolation of Pasteurella multocida from the calves^, lungs.

Animal Model:	Hycole strain rabbits aged 33-37 days with epizootic rabbit enteropathy^[2]
Dosage:	20 or 35 parts per million (ppm)
Administration:	Feed administration; 21 days
Result:	Reduced rabbit mortality. Epizootic rabbit enteropathy mortality was 23% in untreated rabbits and 11% and 7.6% in rabbits treated with 20 and 35 ppm doses, respectively. Had no detrimental effects on appetite, weight gain or feed conversion rate.

VALNEMULIN HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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VALNEMULIN HYDROCHLORIDE Suppliers

Canada 1 China 274 France 1 Germany 1 India 5 Japan 2 Switzerland 1 United Kingdom 1 United States 14 Global 300

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768836
Email: 1791901229@qq.com
Country: China
ProdList: 6950
Advantage: 52

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4747
Advantage: 58

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

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View Lastest Price from VALNEMULIN HYDROCHLORIDE manufacturers

Wuhan JiyunZen Tech Co., Ltd.

Product: VALNEMULIN HYDROCHLORIDE 133868-46-9
Price: US $5.00-0.50/KG
Min. Order: 1KG
Purity: 99% hplc
Supply Ability: 500TONS
Release date: 2025-05-14

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Valnemulin hydrochloride 133868-46-9
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1000kg
Release date: 2021-09-10

Hebei Chuanghai Biotechnology Co., Ltd

Product: VALNEMULIN HYDROCHLORIDE 133868-46-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-01

133868-46-9, VALNEMULIN HYDROCHLORIDERelated Search:

Tilmicosin VALNEMULIN FOR PEAK IDENTIFICATION Doxycycline hydrochloride Doxycycline hyclate Tiamulin Pleuromulin Esculetin Chlortetracycline hydrochloride VALNEMULIN HYDROGEN TARTRATE VALNEMULIN IMPURITY E Rocuronium bromide VALNEMULIN VALNEMULIN HYDROCHLORIDE CYCLOUNDECANONE ISOOCTYL THIOGLYCOLATE 2-Ethylhexyl mercaptoacetate H-D-VAL-NH2 HCL ACETIC ACID, MERCAPTO-, ISOTRIDECYLESTER

econor

VALNEMULIN HCL

VALNEMULIN HYDROCHLORIDE

Etodoiac

Acetic acid,[[2-[[(2R)-2-aMino-3-Methyl-1-oxobutyl]aMino]-1,1-diMethylethyl]thio]-,(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetraMethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-ylester, Monohydrochloride (9CI)

ValneMulin hyd

Acetic acid, 2-[[2-[[(2R)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester, hydrochloride (1:1)

Valnemulin hydrochloride Solution, 100ppm

VALNEMULIN HYDROCH

Valnemulin Hydrochloride, ?>99.0%

Valnemulin hydrochloride CRS

Valnemulin Hydrochlorid

(3aR,5R,7S,8S,9R,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-((1-((R)-2-amino-3-methylbutanamido)-2-methylpropan-2-yl)thio)acetate hydrochloride

VALNEMULIN HYDROCHLORIDE USP/EP/BP

Valnemulin HCl 50% premix

Vonimorin hydrochloride

UNII-W1GDP58BNQ

Valnemulin hydrochloride in methanol

C17899970 Valnemulin hydrochloride

Codeine Phosphate Impurity 4 (Codeine Phosphate EP Impurity D)

Vonimolin hydrochloride 133868-46-9

Valnemulin hydrochloride, 10 mM in DMSO

Valnemulin Hydrocloride

133868-46-9

C31H52N2O5SHCl

C31H53ClN2O5S

API

Inhibitors

133868-46-9