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XY1

Product Name
XY1
CAS No.
1624117-53-8
Chemical Name
XY1
Synonyms
XY1;XY1 NEW;CS-2431;XY1; XY 1;XY1;XY-1;XY 1;XY1, 10 mM in DMSO;XY-1 (Negative of SGC-707);N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea;N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea;Inhibitor,XY 1,inhibit,XY-1,Histone Methyltransferase,XY1
CBNumber
CB23060845
Molecular Formula
C17H19N3O2
Formula Weight
297.35
MOL File
1624117-53-8.mol
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XY1 Property

Boiling point:
514.8±42.0 °C(Predicted)
Density 
1.284±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMF: 10 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form 
A crystalline solid
pka
12.62±0.46(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17518
Product name
XY1
Purity
≥98%
Packaging
5mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
17518
Product name
XY1
Purity
≥98%
Packaging
10mg
Price
$198
Updated
2024/03/01
Cayman Chemical
Product number
17518
Product name
XY1
Purity
≥98%
Packaging
25mg
Price
$467
Updated
2024/03/01
Cayman Chemical
Product number
17518
Product name
XY1
Purity
≥98%
Packaging
50mg
Price
$826
Updated
2024/03/01
Tocris
Product number
5450
Product name
XY1
Purity
≥98%(HPLC)
Packaging
50
Price
$645
Updated
2021/12/16
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XY1 Chemical Properties,Usage,Production

Description

Protein arginine N-methyltransferase 3 (PRMT3, ) is a predominantly cytoplasmic enzyme that is constitutively expressed. SGC707 is a potent, selective allosteric inhibitor of PRMT3 (IC50 = 50 nM). It inhibits the methylation of histones in cells with an IC50 value below 1 μM. XY1 is a close analog of SGC707 that is completely inactive against PRMT3 at concentrations as high as 100 μM. It is intended to be used as a negative control for SGC707 in studies involving PRMT3 action. See the Structural Genomics Consortium (SGC) website for more information.

Uses

XY1 acts as a close analog of SGC707 that is completely inactive against PRMT3, inhibiting the methylation of histones in cells.

storage

Store at +4°C

XY1 Preparation Products And Raw materials

Raw materials

Preparation Products

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XY1 Suppliers

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View Lastest Price from XY1 manufacturers

Career Henan Chemical Co
Product
N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea 1624117-53-8
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-01-01

1624117-53-8, XY1Related Search:


  • XY1
  • XY-1 (Negative of SGC-707)
  • XY1;XY-1;XY 1
  • CS-2431
  • 1-(naphthalen-2-yl)-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl]urea
  • XY1 NEW
  • N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea
  • XY1; XY 1
  • Urea, N-2-naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-
  • Inhibitor,XY 1,inhibit,XY-1,Histone Methyltransferase,XY1
  • N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea
  • XY1, 10 mM in DMSO
  • 1624117-53-8
  • API