4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate

Product Name: 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
CAS No.: 1577222-14-0
Chemical Name: 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
Synonyms: ALKS-8700;Diroximel Fumarete;diroximel fumarate;Diroximel Fumarete(ALKS-8700);Diroximel Fumarate DR Pellets;5-dioxopyrrolidin-1-yl)ethyl methyl fumarate;2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate;2-(2,5-Dioxopyrrolidin-1-Yl)Ethyl Methyl Fumarate(WXC04774);2-(2,5-dioxopyrrolidin-1-yl)ethyl (E)-4-chloro-4-oxobut-2-enoate;4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
CBNumber: CB23070732
Molecular Formula: C11H13NO6
Formula Weight: 255.22
MOL File: 1577222-14-0.mol

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4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate Property

Melting point:: 96 - 99°C
Boiling point:: 441.0±25.0 °C(Predicted)
Density: 1.319±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Ethyl Acetate (Slightly)
form: Solid
pka: -1.60±0.20(Predicted)
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29111
Product name: Diroximel Fumarate
Packaging: 5mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 29111
Product name: Diroximel Fumarate
Packaging: 50mg
Price: $553
Updated: 2024/03/01

Cayman Chemical

Product number: 29111
Product name: Diroximel Fumarate
Packaging: 10mg
Price: $143
Updated: 2024/03/01

Cayman Chemical

Product number: 29111
Product name: Diroximel Fumarate
Packaging: 25mg
Price: $336
Updated: 2024/03/01

AK Scientific

Product number: 6016DW
Product name: Diroximelfumarate
Packaging: 50mg
Price: $714
Updated: 2021/12/16

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4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate Chemical Properties,Usage,Production

Description

Diroximel fumarate is a prodrug form of monomethyl fumarate . It undergoes esterase cleavage in the gut to release monomethyl fumarate. Formulations containing diroximel fumarate have been used in the treatment of relapsing-remitting multiple sclerosis.

Uses

Diroximel Fumarate is a novel oral fumarate in development for the treatment of patients with relapsing forms of multiple sclerosis.

4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate Preparation Products And Raw materials

Raw materials

Preparation Products

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4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate Suppliers

China 76 India 9 Israel 1 United States 8 Global 94

Shandong Jirun Biomedical Technology Co., Ltd.

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Amadis Chemical Company Limited

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Medi-tech Bioscientific Co., Ltd.

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View Lastest Price from 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate manufacturers

Career Henan Chemica Co

Product: 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate 1577222-14-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: MIn98%HPLC/LC
Supply Ability: 100KGS
Release date: 2020-10-29

1577222-14-0, 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioateRelated Search:

1-Methylpyrrolidine

(2E)-2-Butenedioic acid 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester

2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate

Diroximel Fumarete

2-(2,5-Dioxopyrrolidin-1-Yl)Ethyl Methyl Fumarate(WXC04774)

4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate

ALKS-8700

diroximel fumarate

(E)-but-2-enedioic acid 2-(2,5-dioxo-pyrrolidin-1-yl)ethyl ester methyl ester

Diroximel Fumarete(ALKS-8700)

DIROXIMEL FUMARATE; ALKS8700; ALKS 8700; ALKS-8700;2-(2;5-DIOXOPYRROLIDIN-1-YL)ETHYL METHYL FUMARATE

5-dioxopyrrolidin-1-yl)ethyl methyl fumarate

2-Butenedioic acid (2E)-, 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester

DiroximelFumarete,ALKS-8700,4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate

Diroximel Fumarate DR Pellets

Inhibitor,Diroximel,ALKS-8700,ALKS 8700,ALKS8700,BIIB 098,Diroximel fumarate,inhibit,BIIB098,BIIB-098

2-(2,5-dioxopyrrolidin-1-yl)ethyl (E)-4-chloro-4-oxobut-2-enoate

1577222-14-0

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