Azido-PEG9-alcohol
- Product Name
- Azido-PEG9-alcohol
- CAS No.
- 1984776-37-5
- Chemical Name
- Azido-PEG9-alcohol
- Synonyms
- Azido-PEG9-alcohol;26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol;N3-PEG9-OH/3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-azido-;Azido-PEG-9-alcohol,Azido PEG9 alcohol,PROTAC Linkers,Inhibitor,AzidoPEG9alcohol,inhibit
- CBNumber
- CB23134166
- Molecular Formula
- C18H37N3O9
- Formula Weight
- 439.51
- MOL File
- 1984776-37-5.mol
Azido-PEG9-alcohol Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in Water, DMSO, DCM, DMF
- form
- Liquid
- color
- Light yellow to yellow
N-Bromosuccinimide Price
- Product number
- BP-22976
- Product name
- Azido-PEG9-alcohol
- Purity
- 98%
- Packaging
- 500mg
- Price
- $390
- Updated
- 2021/12/16
- Product number
- B-0911
- Product name
- N3-PEG9-OH
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $220
- Updated
- 2021/12/16
- Product number
- 4366209
- Product name
- N3-PEG9-OH
- Purity
- min.97%
- Packaging
- 250mg
- Price
- $313
- Updated
- 2021/12/16
- Product number
- B-0911
- Product name
- N3-PEG9-OH
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $330
- Updated
- 2021/12/16
Azido-PEG9-alcohol Chemical Properties,Usage,Production
Description
Azido-PEG9-alcohol is a click chemistry crosslinker with an azide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne such as , BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Uses
Azido-PEG9-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG9-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG9-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG9-alcohol Suppliers
- Tel
- +1-5166625404;
- Fax
- 1-516-927-0118
- Info@alfa-chemistry.com
- Country
- United States
- ProdList
- 20405
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
View Lastest Price from Azido-PEG9-alcohol manufacturers
- Product
- azido-PEG9-OH 1984776-37-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23