ChemicalBook > CAS DataBase List > (1R,2S,3S)-Aprepitant
(1R,2S,3S)-Aprepitant
- Product Name
- (1R,2S,3S)-Aprepitant
- CAS No.
- 172822-28-5
- Chemical Name
- (1R,2S,3S)-Aprepitant
- Synonyms
- SM001F;(2S,3S,1’R)-Aprepitant;Aretetan Impurity-(RSS);Aprepitant (R,S,S)-Isomer;Aprepitant Impurity - (RSS);(R,S,S)-Enantiomer Aprepitant;Aprepitant Impurity 6(R,S,S-Isomer);Aprepitant Intermediate Impurity -(RSS);Aprepitant impurity 7/(1R,2S,3S)-Aprepitant;5-([(2S,3S)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one
- CBNumber
- CB23146512
- Molecular Formula
- C23H21F7N4O3
- Formula Weight
- 534.43
- MOL File
- 172822-28-5.mol
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(1R,2S,3S)-Aprepitant Property
- Density
- 1.51±0.1 g/cm3(Predicted)
- pka
- 8.06±0.20(Predicted)
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N-Bromosuccinimide Price
TRC
- Product number
- A729770
- Product name
- (2S,3S,1’R)-Aprepitant
- Packaging
- 25mg
- Price
- $2365
- Updated
- 2021/12/16
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(1R,2S,3S)-Aprepitant Chemical Properties,Usage,Production
Uses
(2S,3S,1’R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. (2S,3S,1’R)-Aprepitant is also a useful synthetic intermediate in the synthesis of morpholine tachykinin receptor antagonist prodrugs.
(1R,2S,3S)-Aprepitant Preparation Products And Raw materials
Raw materials
Preparation Products
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(1R,2S,3S)-Aprepitant Suppliers
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View Lastest Price from (1R,2S,3S)-Aprepitant manufacturers
ShenZhen H&D Pharmaceutical Technology Co., LTD
- Product
- Aprepitant Impurity 22 172822-28-5
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 98%
- Supply Ability
- 500mg
- Release date
- 2024-06-11
172822-28-5, (1R,2S,3S)-AprepitantRelated Search:
Aprepitant
5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol
Benzyl dihydrogen phosphate
(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
Aprepitant Impurity 19
[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine
Fosaprepitant Impurity 6
Aprepitant
ent-Aprepitant
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
Aprepitant
1,1,1-Trimethoxy-2-chloroethane
Aprepitant
Defluoro Aprepitant
Aprepitant Impurity B HCl
Aprepitant Impurity 11 HCl
Aprepitant Impurity 2