N,N'-DICYCLOHEXYLUREA

ChemicalBook > CAS DataBase List > N,N'-DICYCLOHEXYLUREA

N,N'-DICYCLOHEXYLUREA

Product Name: N,N'-DICYCLOHEXYLUREA
CAS No.: 2387-23-7
Chemical Name: N,N'-DICYCLOHEXYLUREA
Synonyms: 1,3-DICYCLOHEXYLUREA;Indapamide Impurity 1;Dicyclohexylcarbodiamide;NSC 30023;NSC 17013;AURORA KA-3582;Lomustine USP RC C;Lomustine Impurity C;N,N'-DICYCLOHEXYLUREA;n,n’-dicyclohexyl-ure
CBNumber: CB2314754
Molecular Formula: C13H24N2O
Formula Weight: 224.34
MOL File: 2387-23-7.mol

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N,N'-DICYCLOHEXYLUREA Property

Melting point:: 232-233 °C(lit.)
Boiling point:: 408℃
Density: 1.02
refractive index: 1.4832 (estimate)
Flash point:: 158℃
storage temp.: 2-8°C
solubility: DMSO (Slightly, Heated), Methanol (Slightly)
pka: 13.89±0.20(Predicted)
form: Liquid
color: Clear
Stability:: Hygroscopic
InChIKey: ADFXKUOMJKEIND-UHFFFAOYSA-N
CAS DataBase Reference: 2387-23-7(CAS DataBase Reference)
EPA Substance Registry System: N,N'-Dicyclohexylurea (2387-23-7)

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Safety

Hazard Codes: Xn,N
Risk Statements: 22-51/53
Safety Statements: 61
WGK Germany: 3
TSCA: Yes
HS Code: 29242100

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2924
Product name: Lomustine Related Compound C
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 500MG
Price: $575
Updated: 2024/03/01

Sigma-Aldrich

Product number: D80800
Product name: N,N′-Dicyclohexylurea
Purity: 98%
Packaging: 25g
Price: $140
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1369442
Product name: Lomustine Related Compound C
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25mg
Price: $1500
Updated: 2024/03/01

TCI Chemical

Product number: D0441
Product name: 1,3-Dicyclohexylurea
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $37
Updated: 2024/03/01

TCI Chemical

Product number: D0441
Product name: 1,3-Dicyclohexylurea
Purity: >98.0%(GC)(T)
Packaging: 500g
Price: $274
Updated: 2024/03/01

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N,N'-DICYCLOHEXYLUREA Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

N,N''-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C.

Definition

ChEBI: 1,3-dicyclohexylurea is a member of ureas.

Preparation

An excess of dry ice (200 g) was added gradually to a solution of dicyclohexylcarbodiimide (2.06 g, 0.01 mol), cyclohexylamine (1.98 g, 0.02 mol), and triethylamine (2.2 g, 0.02 mol) in THF at 75 ℃ over a period of 8 h. After stirring for 8 h, the reaction mixture was concentrated under reduced pressure and the resultant precipitate was collected. Fractional recrystallization of the precipitate from acetone/methanol gave N,N'-dicyclohexylurea; yield 2.2 g (98% based on dicyclohexylcarbodiimide and cyclohexylamine).

Synthesis Reference(s)

The Journal of Organic Chemistry, 61, p. 4175, 1996 DOI: 10.1021/jo9522825

N,N'-DICYCLOHEXYLUREA Preparation Products And Raw materials

Raw materials

Cyclohexylamine 3-Methyl-1-butanol

Preparation Products

Dicyclohexylcarbodiimide

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View Lastest Price from N,N'-DICYCLOHEXYLUREA manufacturers

Career Henan Chemical Co

Product: N,N'-DICYCLOHEXYLUREA 2387-23-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 25kg
Release date: 2019-07-12

Career Henan Chemical Co

Product: N,N'-DICYCLOHEXYLUREA 2387-23-7
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-04

2387-23-7, N,N'-DICYCLOHEXYLUREARelated Search:

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AURORA KA-3582

n,n’-dicyclohexyl-ure

N,N'-DICYCLOHEXYLUREA

1,3-DICYCLOHEXYLUREA

N,N,-Dicyclohexylurea98.%

Dicyclohexylcarbodiamide

N,N'-Carbonylbis(cyclohexanamine)

NSC 17013

NSC 30023

LoMustine Related CoMpound C

Lomustine EP Impurity B

5-cyanobenzene-1,3-dicarboxylic acid

1,3-Dicyclohexylurea for synthesis

Indapamide Impurity 1

1,3-Dicyclohexylurea &gt

Lomustine USP RC C

Urea, N,N'-dicyclohexyl-

Lomustine Related Compound C (1,3-Dicyclohexylurea) (1369442)

Lomustine USP Related Compound C

Lomustine Impurity C

Lomustine EP Impurity C

Lomustine Impurity 3(Lomustine EP Impurity C)(Lomustine USP RC C)

1,3-dicyclohexylurea - impurity

1,3-Dicyclohexylurea, ≥ 98.0%

n,n''-dicyclohexylurea

N,N'-DICYCLOHEXYLUREA

2387-23-7

C13H24N2O

C6H11NHCONHC6H11

Organic Building Blocks

Ureas

Building Blocks

Carbonyl Compounds

Finasteride

Carbonyl Compounds

Organic Building Blocks

Ureas