m-PEG3-Sulfone-PEG2-OH
- Product Name
- m-PEG3-Sulfone-PEG2-OH
- CAS No.
- 1919045-00-3
- Chemical Name
- m-PEG3-Sulfone-PEG2-OH
- Synonyms
- m-PEG3-Sulfone-PEG3;m-PEG3-Sulfone-PEG2-OH;3,6,12,15,18-Pentaoxa-9-thianonadecan-1-ol, 9,9-dioxide
- CBNumber
- CB23163012
- Molecular Formula
- C13H28O8S
- Formula Weight
- 344.42
- MOL File
- 1919045-00-3.mol
m-PEG3-Sulfone-PEG2-OH Property
- Boiling point:
- 498.2±45.0 °C(Predicted)
- Density
- 1.173±0.06 g/cm3(Predicted)
- pka
- 14.36±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-23180
- Product name
- m-PEG3-Sulfone-PEG2-OH
- Purity
- 98%
- Packaging
- 100mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BP-23180
- Product name
- m-PEG3-Sulfone-PEG2-OH
- Purity
- 98%
- Packaging
- 250mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- BP-23180
- Product name
- m-PEG3-Sulfone-PEG2-OH
- Purity
- 98%
- Packaging
- 500mg
- Price
- $690
- Updated
- 2021/12/16
m-PEG3-Sulfone-PEG2-OH Chemical Properties,Usage,Production
Description
m-PEG3-Sulfone-PEG2-OH is a PEG linker containing sulfone and hydroxyl moieties. The sulfone can react with thiol groups of proteins. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Uses
m-PEG3-Sulfone-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
m-PEG3-Sulfone-PEG2-OH Preparation Products And Raw materials
Raw materials
Preparation Products
m-PEG3-Sulfone-PEG2-OH Suppliers
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View Lastest Price from m-PEG3-Sulfone-PEG2-OH manufacturers
- Product
- m-PEG3-Sulfone-PEG2-OH 1919045-00-3
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >95.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-28