m-PEG3-Sulfone-PEG4-propargyl

Product Name: m-PEG3-Sulfone-PEG4-propargyl
CAS No.: 2055041-02-4
Chemical Name: m-PEG3-Sulfone-PEG4-propargyl
Synonyms: m-PEG3-Sulfone-PEG4-propargyl;2,5,8,14,17,20,23-Heptaoxa-11-thiahexacos-25-yne, 11,11-dioxide
CBNumber: CB43163016
Molecular Formula: C18H34O9S
Formula Weight: 426.52
MOL File: 2055041-02-4.mol

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m-PEG3-Sulfone-PEG4-propargyl Property

Boiling point:: 536.0±50.0 °C(Predicted)
Density: 1.137±0.06 g/cm3(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23179
Product name: m-PEG3-Sulfone-PEG4-propargyl
Purity: 98%
Packaging: 100mg
Price: $280
Updated: 2021/12/16

BroadPharm

Product number: BP-23179
Product name: m-PEG3-Sulfone-PEG4-propargyl
Purity: 98%
Packaging: 250mg
Price: $450
Updated: 2021/12/16

BroadPharm

Product number: BP-23179
Product name: m-PEG3-Sulfone-PEG4-propargyl
Purity: 98%
Packaging: 500mg
Price: $690
Updated: 2021/12/16

BroadPharm

Product number: BP-23179
Product name: m-PEG3-Sulfone-PEG4-propargyl
Purity: 98%
Packaging: 1g
Price: $1300
Updated: 2021/12/16

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m-PEG3-Sulfone-PEG4-propargyl Chemical Properties,Usage,Production

Description

m-PEG3-Sulfone-PEG4-propargyl is a sulfonated PEG linker containing a propargyl group. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG3-Sulfone-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG3-Sulfone-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

m-PEG3-Sulfone-PEG4-propargyl Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG3-Sulfone-PEG4-propargyl Suppliers

China 16 United States 3 Global 19

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
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Alpha Biopharmaceuticals Co., Ltd

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TargetMol Chemicals Inc.

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Nextpeptide Inc

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Email: sales@nextpeptide.com
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Zhengzhou Akem Chemical Co., Ltd

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Beijing Jin Ming Biotechnology Co., Ltd.

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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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Jilin Chinese Academy of Sciences-yanshen Technology

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Nantong Hanfang Biotechnology Co. , Ltd.

Tel: hanfangpharma@126.com; 18616537568
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View Lastest Price from m-PEG3-Sulfone-PEG4-propargyl manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: m-PEG3-Sulfone-PEG4-propargyl 2055041-02-4
Price: US $0.00/mg
Min. Order: 500mg
Purity: >95.00%
Supply Ability: 500mg
Release date: 2024-03-28

2055041-02-4, m-PEG3-Sulfone-PEG4-propargylRelated Search:

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m-PEG3-Sulfone-PEG4-propargyl

2,5,8,14,17,20,23-Heptaoxa-11-thiahexacos-25-yne, 11,11-dioxide

2055041-02-4

C18H34O9S