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m-PEG3-Sulfone-PEG2-OH

Product Name
m-PEG3-Sulfone-PEG2-OH
CAS No.
1919045-00-3
Chemical Name
m-PEG3-Sulfone-PEG2-OH
Synonyms
m-PEG3-Sulfone-PEG3;m-PEG3-Sulfone-PEG2-OH;3,6,12,15,18-Pentaoxa-9-thianonadecan-1-ol, 9,9-dioxide
CBNumber
CB23163012
Molecular Formula
C13H28O8S
Formula Weight
344.42
MOL File
1919045-00-3.mol
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m-PEG3-Sulfone-PEG2-OH Property

Boiling point:
498.2±45.0 °C(Predicted)
Density 
1.173±0.06 g/cm3(Predicted)
pka
14.36±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23180
Product name
m-PEG3-Sulfone-PEG2-OH
Purity
98%
Packaging
100mg
Price
$280
Updated
2021/12/16
BroadPharm
Product number
BP-23180
Product name
m-PEG3-Sulfone-PEG2-OH
Purity
98%
Packaging
250mg
Price
$450
Updated
2021/12/16
BroadPharm
Product number
BP-23180
Product name
m-PEG3-Sulfone-PEG2-OH
Purity
98%
Packaging
500mg
Price
$690
Updated
2021/12/16
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m-PEG3-Sulfone-PEG2-OH Chemical Properties,Usage,Production

Description

m-PEG3-Sulfone-PEG2-OH is a PEG linker containing sulfone and hydroxyl moieties. The sulfone can react with thiol groups of proteins. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Uses

m-PEG3-Sulfone-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

m-PEG3-Sulfone-PEG2-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG3-Sulfone-PEG2-OH Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
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View Lastest Price from m-PEG3-Sulfone-PEG2-OH manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
m-PEG3-Sulfone-PEG2-OH 1919045-00-3
Price
US $0.00/mg
Min. Order
500mg
Purity
>95.00%
Supply Ability
500mg
Release date
2024-03-28