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WAY-151932

Product Name
WAY-151932
CAS No.
220460-92-4
Chemical Name
WAY-151932
Synonyms
VNA-932;WAY-151932;WAY-VNA 932;WAY151932,WAY 151932;Methanone, [2-chloro-4-(3-methyl-1H-pyrazol-1-yl)phenyl]-5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-yl-
CBNumber
CB23175600
Molecular Formula
C23H19ClN4O
Formula Weight
402.88
MOL File
220460-92-4.mol
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WAY-151932 Property

Boiling point:
630.6±55.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
0.04±0.12(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-6661
Product name
WAY-151932
Packaging
1mg
Price
$550
Updated
2021/12/16
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WAY-151932 Chemical Properties,Usage,Production

Biological Activity

WAY-151932 is an antidiuretic hormone V2 receptor agonist with IC50 of 80.3 and 778 nM in human V2 and V1a binding assays, respectively.

in vitro

WAY-151932 (VNA-932) stimulates cAMP formation in LV2 cells expressing the hV 2 receptors in a dose-dependent manner with an EC 50 of 0.74±0.07 nM.

in vivo

Oral administration of WAY-151932 (VNA-932) to water-loaded conscious rats produces a dose-dependent decrease in urine volume (ED 50 =0.14 mg/kg, 2.5% starch in water vehicle) and a corresponding increase in osmolality without altering the urine electrolyte excretion profile.

target

IC50: 80.3 nM (human-V2 binding), 778 nM (human-V1a binding)

WAY-151932 Preparation Products And Raw materials

Raw materials

Preparation Products

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WAY-151932 Suppliers

China 5 United States 3 Global 8
MedChemexpress LLC
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220460-92-4, WAY-151932Related Search:

BenzenesulfonaMide, 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoroMethyl)- CYCLOHEXANECARBOXAMIDE, N-[2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-2-PYRIDINYL-, HYDROCHLORIDE (1:3) WAY 208466 dihydrochloride WAY-204688 WAY-600 MAY-262611 7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol

  • WAY-151932
  • VNA-932
  • Methanone, [2-chloro-4-(3-methyl-1H-pyrazol-1-yl)phenyl]-5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-yl-
  • WAY-VNA 932
  • WAY151932,WAY 151932
  • 220460-92-4