ChemicalBook > CAS DataBase List > L-Cysteine methyl ester hydrochloride

L-Cysteine methyl ester hydrochloride

Product Name: L-Cysteine methyl ester hydrochloride
CAS No.: 18598-63-5
Chemical Name: L-Cysteine methyl ester hydrochloride
Synonyms: H-Cys-Ome;Methyl L-Cysteinate Hydrochloride;(R)-Cysteine Methyl Ester Hydrochloride;actiol;l.j.48;zeotin;acdrile;pectite;visclair;M-Cysten
CBNumber: CB2327369
Molecular Formula: C4H10ClNO2S
Formula Weight: 171.65
MOL File: 18598-63-5.mol

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L-Cysteine methyl ester hydrochloride Property

Melting point:: 142 °C (dec.)(lit.)
alpha: -2.25 º (c=5, 1 N HCl)
Density: 1.232 (estimate)
FEMA: 4781 | L-CYSTEINE METHYL ESTER HYDROCHLORIDE
refractive index: -2.5 ° (C=20, MeOH)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol, Water (Slightly)
form: Crystalline Powder
color: White
biological source: synthetic
optical activity: [α]20/D 1.8°, c = 10 in methanol
Water Solubility: Soluble in water
Merck: 13,5809
BRN: 3685824
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: WHOHXJZQBJXAKL-DFWYDOINSA-N
CAS DataBase Reference: 18598-63-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 2
RTECS: HA2460000
F: 1-10
HS Code: 29309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H303May be harmfulif swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 410209
Product name: L-Cysteine methyl ester hydrochloride
Purity: 98%
Packaging: 5g
Price: $53.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: 410209
Product name: L-Cysteine methyl ester hydrochloride
Purity: 98%
Packaging: 25g
Price: $78.1
Updated: 2025/07/31

TCI Chemical

Product number: C0577
Product name: L-Cysteine Methyl Ester Hydrochloride
Purity: >99.0%(T)
Packaging: 5g
Price: $17
Updated: 2023/06/20

TCI Chemical

Product number: C0577
Product name: L-Cysteine Methyl Ester Hydrochloride
Purity: >99.0%(T)
Packaging: 25g
Price: $32
Updated: 2022/04/27

TCI Chemical

Product number: C0577
Product name: L-Cysteine Methyl Ester Hydrochloride
Purity: >99.0%(T)
Packaging: 500g
Price: $273
Updated: 2022/04/27

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L-Cysteine methyl ester hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

A mucolytic. An effective drug for the treatment of liver failure. Shown to effectively inhibit the binding of ethynylestradiol metabolites to protein and nucleic acids.

Uses

Mucolytic agent

Uses

L-Cysteine methyl ester hydrochloride is a biochemical shown to inhibit binding of ethynylestradiol metabolites to protein and nucleic acids. It used in the synthesis of peptides, Preparation of thiazolidine-4-carboxylates with carbonyl compounds.

Definition

ChEBI: Mecysteine hydrochloride is an alpha-amino acid ester.

Preparation

L-Cysteine methyl ester hydrochloride is prepared by esterification of L-cysteine hydrochloride monohydrate with methanol in the presence of hydrogen chloride.

reaction suitability

reaction type: solution phase peptide synthesis

Trade name

Acthiol (Joullié, France), Actiol (Lirca, Italy), Visclair (Sinclair, UK), Aslos-C (Nissin, J), Epectan (Seiko, Japan), Moltanine (Tohok.-Tokyo Tanabe, Japan), Radcol (Nippon Universal, Japan), Sekinin (Tokyo Hosei, Japan).

Synthesis

67-56-1

52-89-1

18598-63-5

3 mL of sulfoxide chloride (SOCl2) was slowly added dropwise to 35 mL of methanol under nitrogen protection in an ice bath. Subsequently, the reaction mixture was stirred at room temperature for 1 hour. After that, 1 g of L-cysteine hydrochloride monohydrate (Cys-HCl-H2O) was added to the above solution in batches. The reaction was continued with the mixed solution at room temperature for 3 hours and then heated to reflux for 1 hour. Upon completion of the reaction, the volatile components and solvent were removed by distillation under reduced pressure, and the resulting residue was recrystallized using a solvent mixture of methanol-dichloromethane (CH3OH-CH2Cl2) to give 0.84 g of the white solid product L-cysteine methyl ester hydrochloride in 85.9% yield. The product was analyzed by infrared spectroscopy (IR, KBr press) showing characteristic absorption peaks: 3040.4 cm-1 (strong, NH2 stretching vibration), 1709.7 cm-1 (strong, C=O stretching vibration), 2580 cm-1 (weak, SH stretching vibration). The nuclear magnetic resonance hydrogen spectrum (1H NMR, D2O as solvent, TMS as internal standard) data were as follows: δ 4.453 (t, 1H, CH, J = 5.2 Hz), 3.871 (s, 3H, CH3), 3.164 (t, 2H, CH2, J = 6.4 Hz). Elemental analysis results: Calculated values (C4H10NO2SCCl): C, 27.99%; H, 5.87%; N, 8.16%. Measured values: C, 28.11%; H, 6.01%; N, 8.08%.

References

[1] European Journal of Medicinal Chemistry, 2014, vol. 74, p. 199 - 215
[2] Journal of Organic Chemistry, 2013, vol. 78, # 9, p. 4270 - 4277
[3] Tetrahedron Asymmetry, 2000, vol. 11, # 21, p. 4255 - 4261
[4] Journal of the American Chemical Society, 2008, vol. 130, # 15, p. 5052 - 5053
[5] European Journal of Medicinal Chemistry, 2012, vol. 55, p. 176 - 187,12

L-Cysteine methyl ester hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from L-Cysteine methyl ester hydrochloride manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: L-Cysteine methyl ester hydrochloride 18598-63-5
Price: US $1.00-4.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2025-09-04

WUHAN FORTUNA CHEMICAL CO., LTD

Product: L-Cysteine methyl ester hydrochloride 18598-63-5
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 500kgs
Release date: 2021-09-26

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: H-L-Cys-OMe.HCl 18598-63-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-03-24

18598-63-5, L-Cysteine methyl ester hydrochlorideRelated Search:

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L-Cysteine Methyl ester hydrochloride 98%

L-Cysteine methyl ester hydrochloride(Acdrile)

L-Cys-OMe·HCl

L-Cysteine methyl ester hydrochloride≥ 98.5% (Titration)

MECYSTEINE HYDROCHLORIDE

methyl cysteine hydrochloride

H-CYS-OME HCL

H-CYS(ME)OH HYDROCHLORIDE

L-CYSTEINE METHYL ESTER HYDROCHLORIDE

L-CYSTEINE METHYL ESTER MONOHYDROCHLORIDE

L-CYSTEIN METHYL ESTER HYDROCHLORIDE

acdrile

actiol

l.j.48

methylester,hydrochloride,l-cystein

pectite

visclair

zeotin

Methyl α-aMino-β-Mercaptopropionate hydrochloride

Methyl β-Mercaptoalanine hydrochloride

L-Cysteine Methyl ester hydrochloride, 98% 25GR

L-Cysteine Methyl ester hydrochloride, 98% 5GR

(R)-Cysteine Methyl Ester Hydrochloride

Methyl (R)-2-AMino-3-Mercaptopropanoate Hydrochloride

Methyl L-Cysteinate Hydrochloride

NSC 161611

(R)-Methyl 2-aMino-3-Mercaptopropanoate hydrochloride

L-CYSTEINE METHYL ESTER HYDROCHLORIDECRY STALLINE

L-CYSTEINE METHYL ESTER HYDROCHLORIDE, 9 8%

Mecysteine HCL

CYS-OME.HCL

L-Cysteine Methyl Ester HCl

L-Cystein methyl ester HCl

H-CYS(ME)-OH . HCL

[(2R)-3-mercapto-1-methoxy-1-oxopropan-2-yl]ammonium

Methyl cysteinate hydrochloride

Cysteine methyl·hydrochloride

L-Cyseinemethyl hydrochloride

L-Methylcyseine hydrochloride

M-Cysten

Methyl L-cysteine hydrochloride

L(-)-Cysteine Mehtyl Ester Hydrochloride

L-Cysteine methyl ester hydrochloride(Cys-Ome·HCl) ,98%

L-Cysteine methyl es

H-Cys-Ome

methyl (2R)-2-amino-3-sulfanylpropanoate,hydrochloride

L-Cysteine Methyl Ester Hydrochloride &gt

(R)-METHYL 2-AMINO-3-MERCAPTOPROPANOATE HCL

-Cysteine methyL

L-Cysteine methyl ester hydrochloride USP/EP/BP

L-Cysteine methyl ester hydrochloride,0.98

H-L-Cys-OMe.HCl

L-Cysteine, methyl ester, hydrochloride (9CI)

L-Cysteine methyl ester hydrochloride, 10 mM in DMSO

<sc>L</sc>-Cysteine methyl ester hydrochloride

18598-63-5

18698-63-5

C4H9NO2SHCl