ChemicalBook > CAS DataBase List > WUWEIZISU C

WUWEIZISU C

Product Name
WUWEIZISU C
CAS No.
61301-33-5
Chemical Name
WUWEIZISU C
Synonyms
WUWEIZISU C;,8-dimethyl-;SCHIZANDRIN C;Schizandrin C-RM;(S)-(-)-Schisandrin C;WUWEIZISU C USP/EP/BP;Schisandrin C >=98% (HPLC);Schisandrin C (Schizandrin-C;Schisandrin C (S)-(-)-Schisandrin C;13,14-dimethoxy-6,7-dimethyl-5,6,7,8-tetrahydro[1,3]benzodio...
CBNumber
CB2327435
Molecular Formula
C22H24O6
Formula Weight
384.42
MOL File
61301-33-5.mol
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WUWEIZISU C Property

Melting point:
122-123℃
Boiling point:
549.2±50.0 °C(Predicted)
Density 
1.232
solubility 
DMSO : 8.33 mg/mL (21.67 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form 
powder
color 
White
LogP
5.623 (est)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27475
Product name
Schisandrin C
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
27475
Product name
Schisandrin C
Packaging
25mg
Price
$1075
Updated
2024/03/01
Cayman Chemical
Product number
27475
Product name
Schisandrin C
Packaging
5mg
Price
$306
Updated
2024/03/01
Cayman Chemical
Product number
27475
Product name
Schisandrin C
Packaging
10mg
Price
$502
Updated
2024/03/01
TRC
Product number
S199050
Product name
SchisandrinC
Packaging
2.5mg
Price
$625
Updated
2021/12/16
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WUWEIZISU C Chemical Properties,Usage,Production

Description

Schisandrin C is a lignan originally isolated from Schizandrae that has diverse biological activities. It decreases viability of U937 cells in a concentration-dependent manner and induces cell cycle arrest at the G1 phase when used at a concentration of 100 μM. Schisandrin C (5-20 μM) decreases hydrogen peroxide-induced cell death and production of reactive oxygen species (ROS) in C2C12 skeletal muscle cells. It also decreases levels of matrix metalloproteinase-2 (MMP-2), MMP-9, COX-2, VCAM-1, IL-1β, and TNF-α in hydrogen peroxide-stimulated C2C12 cells. Schisandrin C decreases lipoteichoic acid-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; ), TNF-α, IL-1β, and IL-6 in mouse primary microglia. In vivo, schisandrin C (200 mg/kg) decreases serum alanine amino transferase (ALT) and aspartate amino transferase (AST) activity, increases hepatic mitochondrial and total glutathione (GSH) levels, and reduces liver injury in a mouse model of acetaminophen-induced liver injury partially via inhibition of the cytochrome P450 (CYP) isoforms CYP2E1, CYP1A2, and CYP3A11.

Uses

Schisandrin C potently inhibits proprotein convertase subtillsin-kexin type 9 (PCSK9) mRNA expression. Also, it displays strong protective effects in SH-SY5Y cells against serum and glucose deprivation (SGD) injury.

WUWEIZISU C Preparation Products And Raw materials

Raw materials

Preparation Products

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WUWEIZISU C Suppliers

China 156 Japan 1 United Kingdom 5 United States 18 USA 1 Global 181
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View Lastest Price from WUWEIZISU C manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Schisandrin C 61301-33-5
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-12-27
Career Henan Chemical Co
Product
WUWEIZISU C 61301-33-5
Price
US $1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-24

61301-33-5, WUWEIZISU CRelated Search:

WUWEIZISU B,WUWEIZISU B 98.0% BY HPLC Schisandrin schisanhenol WUWEIZISU A Schisantherin A (5S)-6α,7β-Dimethyl-1,2,3,11,12-pentamethoxy(5,6,7,8-tetrahydrodibenzo[a,c]cyclooctene)-5α,6β,10-triol 5-benzoate Gomisin A 2-BUTENOIC ACID, 2-METHYL-, (5S,6S,7S,13AS)-5,6,7,13A-TETRAHYDRO-6-HYDROXY-1,2,3,13-TETRAMETHOXY-6,7-DIMETHYLBENZO[3,4]CYCLOOCTA[1,2-F][1,3]BENZODIOXOL-5-YL ESTER, (2Z)- Arisantetralone C 3,5,6,6-tetraMethyl-4,5,5a,6,7,8-hexahydrocyclopenta[c]pentalen-2(1H)-one schisantherin D SchisandraeChinensis polysaccharides Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-1-ol, 5,6,7,8-tetrahydro-2, 3,13-trimethoxy-6,7-dimethyl-, stereoisomer 4,4'-Biphenol 4-HYDROXY-4'-METHOXYBIPHENYL 4,4'-Dimethoxybiphenyl Masoprocol 2,2'-DIMETHOXYBIPHENYL

  • SCHIZANDRIN C
  • WUWEIZISU C
  • ,8-dimethyl-
  • cycloocta(1,2-f:3,4-f’)bis(1,3)benzodioxole6,7,8,9-tetrahydro-1,13-dimethoxy-7
  • (6R,7S,13aS)-5,6,7,8-Tetrahydro-13,14-dimethoxy-6,7-dimethylcycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole
  • (S)-(-)-Schisandrin C
  • Schisandrin C (Schizandrin-C
  • Schisandrin C (S)-(-)-Schisandrin C
  • Cycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole, 5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-, (6R,7S,13aS)-
  • Schisandrin C >=98% (HPLC)
  • WUWEIZISU C USP/EP/BP
  • 13,14-dimethoxy-6,7-dimethyl-5,6,7,8-tetrahydro[1,3]benzodio...
  • (6R,7S)-13,14-Dimethoxy-6,7-dimethyl-5,6,7,8-tetrahydro[1,3]benzodioxolo[5',6':3,4]cycloocta[1,2-f][1,3]benzodioxole
  • Schizandrin C-RM
  • 61301-33-5
  • C22H24O6
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Miscellaneous Natural Products