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Masoprocol

Product Name
Masoprocol
CAS No.
27686-84-6
Chemical Name
Masoprocol
Synonyms
CHX-100;masoprocol;NORHYDROGUAIARETICACID;Masoprocol(nordihydroguaiaretic);meso-4,4'-(2,3- Dimethyltetramethylene)dipyrocatechol;(R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol;4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol;4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol);4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol;rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)
CBNumber
CB6855231
Molecular Formula
C18H22O4
Formula Weight
302.36
MOL File
27686-84-6.mol
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Masoprocol Property

Melting point:
185.5°C
Boiling point:
526.5±45.0 °C(Predicted)
Density 
1.241±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
9.56±0.10(Predicted)
form 
Solid
color 
Off-white to light yellow
LogP
3.710 (est)
EPA Substance Registry System
1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (R*,S*)- (27686-84-6)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FB151770
Product name
1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging
2mg
Price
$59
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB151770
Product name
1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging
5mg
Price
$118
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB151770
Product name
1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging
10mg
Price
$205
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB151770
Product name
1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging
25mg
Price
$409
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001379
Product name
MASOPROCOL
Purity
95.00%
Packaging
500MG
Price
$434
Updated
2021/12/16
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Masoprocol Chemical Properties,Usage,Production

Description

Masoprocol is a lipoxygenase inhibitor launched as a topical agent for the treatment of solar or actinic keratoses. It is the first new topical treatment for pre-malignant skin lesions introduced in twenty years. Masoprocol is obtained from the Larrea tridentata plant and is also under investigation for the treatment of lung, breast, colon and ovarian cancers.

Originator

Chemex (U.S.A.)

Uses

Antineoplastic.

Definition

ChEBI: Masoprocol is the meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase. It has a role as an antineoplastic agent, a lipoxygenase inhibitor, a hypoglycemic agent and a metabolite.

brand name

Actinex (University Of Arizonia Cancer Center).

Masoprocol Preparation Products And Raw materials

Raw materials

Preparation Products

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Masoprocol Suppliers

BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
NCE Biomedical Co.,Ltd.
Tel
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax
+86-27-87599188
Country
China
ProdList
1493
Advantage
55
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15084
Advantage
58
Changzhou Bojia Biomedical Technology Co., Ltd.
Tel
2122619822
Email
czbjpharma@126.com
Country
China
ProdList
18478
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24649
Advantage
58
Shaanxi Dideu Newmaterial Co., Ltd.
Tel
029-87576359 15353716720
Email
1039@dideu.com
Country
China
ProdList
10009
Advantage
58
Shanghai Tachizaki Biomedical Research Center
Tel
18014399201
Email
sales@chemlab-tachizaki.com
Country
China
ProdList
2559
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58

27686-84-6, MasoprocolRelated Search:


  • masoprocol
  • 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol
  • (R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol
  • Masoprocol(nordihydroguaiaretic)
  • NORHYDROGUAIARETICACID
  • CHX-100
  • meso-4,4'-(2,3- Dimethyltetramethylene)dipyrocatechol
  • 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol
  • 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
  • 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol
  • 4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol)
  • rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)
  • 27686-84-6