Masoprocol

Product Name: Masoprocol
CAS No.: 27686-84-6
Chemical Name: Masoprocol
Synonyms: CHX-100;masoprocol;NORHYDROGUAIARETICACID;Masoprocol(nordihydroguaiaretic);meso-4，4'-(2，3- Dimethyltetramethylene)dipyrocatechol;(R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol;4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol;4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol);4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol;rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)
CBNumber: CB6855231
Molecular Formula: C18H22O4
Formula Weight: 302.36
MOL File: 27686-84-6.mol

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Masoprocol Property

Melting point:: 185.5°C
Boiling point:: 526.5±45.0 °C(Predicted)
Density: 1.241±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: Solid
pka: 9.56±0.10(Predicted)
color: Off-white to light yellow
LogP: 3.710 (est)
EPA Substance Registry System: 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (R*,S*)- (27686-84-6)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FB151770
Product name: 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging: 2mg
Price: $59
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB151770
Product name: 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging: 5mg
Price: $118
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB151770
Product name: 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging: 10mg
Price: $205
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB151770
Product name: 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (r*,s*)-
Packaging: 25mg
Price: $409
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0001379
Product name: MASOPROCOL
Purity: 95.00%
Packaging: 500MG
Price: $434
Updated: 2021/12/16

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Masoprocol Chemical Properties,Usage,Production

Description

Masoprocol is a lipoxygenase inhibitor launched as a topical agent for the treatment of solar or actinic keratoses. It is the first new topical treatment for pre-malignant skin lesions introduced in twenty years. Masoprocol is obtained from the Larrea tridentata plant and is also under investigation for the treatment of lung, breast, colon and ovarian cancers.

Chemical Properties

Crystallized from acetic acid, melting point 185～186°C. UV maximum absorption (methanol): 283, 218nm (ε6660, 13400). Soluble in ethanol, methanol, ether or concentrated sulfuric acid, slightly soluble in hot water or chloroform, insoluble in petroleum ether, benzene, toluene or dilute hydrochloric acid. Soluble in dilute alkaline solution and becomes red.

Originator

Chemex (U.S.A.)

Uses

Antineoplastic.

Definition

ChEBI: Masoprocol is the meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase. It has a role as an antineoplastic agent, a lipoxygenase inhibitor, a hypoglycemic agent and a metabolite.

brand name

Actinex (University Of Arizonia Cancer Center).

Masoprocol Preparation Products And Raw materials

Raw materials

Palladium(II) oxide Copper Hydrochloric acid Bromide

Preparation Products

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Masoprocol Suppliers

China 18 Europe 2 Germany 1 United Kingdom 1 United States 5 Global 27

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1493
Advantage: 55

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15083
Advantage: 58

Henan Alfa Chemical Co., Ltd

Tel: +8615838112936
Email: alfa10@alfachem.cn
Country: China
ProdList: 12921
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shaanxi Dideu Newmaterial Co., Ltd.

Tel: 029-63373950 17392213970
Email: 1052@dideu.com
Country: China
ProdList: 9998
Advantage: 58

Shanghai Tachizaki Biomedical Research Center

Tel: 18014399201
Email: sales@chemlab-tachizaki.com
Country: China
ProdList: 2742
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

Beijing Putian Tongchuang Biotechnology Co., Ltd.

Tel: 18201332838
Email: 3032079623@qq.com
Country: China
ProdList: 6695
Advantage: 58

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masoprocol

4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol

(R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol

Masoprocol(nordihydroguaiaretic)

NORHYDROGUAIARETICACID

CHX-100

meso-4，4'-(2，3- Dimethyltetramethylene)dipyrocatechol

4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol

4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol

4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol

4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol)

rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)

27686-84-6