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methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate

Product Name
methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
CAS No.
1421312-36-8
Chemical Name
methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
Synonyms
ROXA-022;Methyl Roxadustat;RSYY(Roxadustat)-20;Roxastat Impurity 13;Roxadustat Impurity 9;Roxadustat Impurities4;Roxadustat Methyl Ester;Roxadustat Methy Ester Impurity;methyl (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycinate;methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
CBNumber
CB23358234
Molecular Formula
C20H18N2O5
Formula Weight
366.37
MOL File
1421312-36-8.mol
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methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate Property

InChI
InChI=1S/C20H18N2O5/c1-12-16-10-14(27-13-6-4-3-5-7-13)8-9-15(16)19(24)18(22-12)20(25)21-11-17(23)26-2/h3-10,24H,11H2,1-2H3,(H,21,25)
InChIKey
QSGJZCCNTOCDRI-UHFFFAOYSA-N
SMILES
C(OC)(=O)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC1=CC=CC=C1)C=C2)=O
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Hazard and Precautionary Statements (GHS)

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methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate Chemical Properties,Usage,Production

Uses

Roxadustat Methyl Ester is used in the preparation of Roxadustat.Roxadustat (H948180) is a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to increase white blood cell levels in blood and hematopoietic progenitor cells in bone marrow.It is used for treatment of anemia in patient with chronic kidney disease.

methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate Suppliers

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View Lastest Price from methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Roxadustat Impurity 13 1421312-36-8
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-26
ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Roxadustat Impurity 13 1421312-36-8
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98%
Supply Ability
500mg
Release date
2024-07-17
Career Henan Chemical Co
Product
methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate 1421312-36-8
Price
US $5.50/KG
Min. Order
2KG
Purity
96%-99%
Supply Ability
100kg
Release date
2019-09-04

1421312-36-8, methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetateRelated Search:


  • ROXA-022
  • methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
  • Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-, methyl ester
  • Roxadustat Impurity 9
  • Roxadustat Methyl Ester
  • methyl (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycinate
  • Roxadustat Impurities4
  • Roxadustat Impurity 2Q: What is Roxadustat Impurity 2 Q: What is the CAS Number of Roxadustat Impurity 2
  • RSYY(Roxadustat)-20
  • N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine methyl ester
  • Methyl Roxadustat
  • Roxadustat Methy Ester Impurity
  • Roxastat Impurity 13
  • 1421312-36-8