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t-Boc-Aminooxy-PEG3-oxyamine

Product Name
t-Boc-Aminooxy-PEG3-oxyamine
CAS No.
2062663-66-3
Chemical Name
t-Boc-Aminooxy-PEG3-oxyamine
Synonyms
Boc-Aminooxy-PEG4-NH2;t-Boc-Aminooxy-PEG3-oxyamine;t-Boc-Aminooxy-PEG3-oxyamine boc;tert-butyl (2-(2-(2-(2-(aminooxy)ethoxy)ethoxy)ethoxy)ethoxy)carbamate;3,6,9,12-Tetraoxa-2-azatetradecanoic acid, 14-(aminooxy)-, 1,1-dimethylethyl ester
CBNumber
CB23364002
Molecular Formula
C13H28N2O7
Formula Weight
324.37
MOL File
2062663-66-3.mol
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t-Boc-Aminooxy-PEG3-oxyamine Property

Density 
1.114±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, sealed storage, away from moisture
solubility 
Soluble in Water, DMSO, DCM, DMF
pka
4.21±0.70(Predicted)
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23462
Product name
t-Boc-Aminooxy-PEG3-oxyamine
Purity
98%
Packaging
100mg
Price
$320
Updated
2021/12/16
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t-Boc-Aminooxy-PEG3-oxyamine Chemical Properties,Usage,Production

Description

t-Boc-Aminooxy-PEG3-oxyamine is a PEG crosslinker with a t-Boc protected aminooxy and a free aminooxy group. The terminal oxyamine group can react with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. t-Boc can be removed under mild acidic conditions. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.

Uses

Boc-Aminooxy-PEG4-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-Aminooxy-PEG3-oxyamine Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-Aminooxy-PEG3-oxyamine Suppliers

Jinan elephant international trading co., LTD
Tel
Fax
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China
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Xi'an Confluore Biological Technology Co., Ltd.
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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Beijing Solarbio Science & Tecnology Co., Ltd.
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Jilin Chinese Academy of Sciences-yanshen Technology
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Henan Mengtai Pharmaceutical Technology Co., Ltd
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Xian confluore Biological Technology Co., Ltd.
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Jilin Chinese Academy of Sciences-yanshen Technology
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View Lastest Price from t-Boc-Aminooxy-PEG3-oxyamine manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
t-Boc-Aminooxy-PEG3-oxyamine 2062663-66-3
Price
US $0.00/mg
Min. Order
500mg
Purity
>98.00%
Supply Ability
500mg
Release date
2024-03-23

2062663-66-3, t-Boc-Aminooxy-PEG3-oxyamineRelated Search:


  • t-Boc-Aminooxy-PEG3-oxyamine
  • tert-butyl (2-(2-(2-(2-(aminooxy)ethoxy)ethoxy)ethoxy)ethoxy)carbamate
  • Boc-Aminooxy-PEG4-NH2
  • 3,6,9,12-Tetraoxa-2-azatetradecanoic acid, 14-(aminooxy)-, 1,1-dimethylethyl ester
  • t-Boc-Aminooxy-PEG3-oxyamine boc
  • 2062663-66-3