Mal-PEG4-Val-Cit-PAB-PNP

Product Name: Mal-PEG4-Val-Cit-PAB-PNP
CAS No.: 2112738-09-5
Chemical Name: Mal-PEG4-Val-Cit-PAB-PNP
Synonyms: Mal-PEG4-Val-Cit-PAB-PNP;4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl (4-nitrophenyl) carbonate;4-((17S,20S)-1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosan-21-amido)benzyl (4-nitrophenyl) carbonate;L-Ornithinamide, N-[15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
CBNumber: CB23373644
Molecular Formula: C40H53N7O15
Formula Weight: 871.89
MOL File: 2112738-09-5.mol

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Mal-PEG4-Val-Cit-PAB-PNP Property

solubility: Soluble in DMSO, DMF
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23668
Product name: Mal-PEG4-Val-Cit-PAB-PNP
Purity: 97%
Packaging: 100mg
Price: $950
Updated: 2021/12/16

Iris Biotech GmbH

Product number: ADC1210
Product name: Mal-PEG(4)-Val-Cit-PAB-PNP
Packaging: 100mg
Price: $1012.5
Updated: 2021/12/16

Ambeed

Product number: A763179
Product name: 4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl(4-nitrophenyl)carbonate
Purity: 95%
Packaging: 100mg
Price: $1242
Updated: 2021/12/16

Ambeed

Product number: A763179
Product name: 4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl(4-nitrophenyl)carbonate
Purity: 95%
Packaging: 250mg
Price: $2110
Updated: 2021/12/16

Ambeed

Product number: A763179
Product name: 4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl(4-nitrophenyl)carbonate
Purity: 95%
Packaging: 1g
Price: $5485
Updated: 2021/12/16

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Mal-PEG4-Val-Cit-PAB-PNP Chemical Properties,Usage,Production

Description

Mal-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker. The Val-Cit linkers can be cleaved by Cathepsin B. Maleimide (Mal) group is reactive toward thiol groups. PEG space improve compound's aqueous solubility. PNP is a good leaving group.

Biological Activity

Mal-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize antibody drug conjugates (ADC).

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

Mal-PEG4-Val-Cit-PAB-PNP Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG4-Val-Cit-PAB-PNP Suppliers

China 27 United States 4 Global 31

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Zhengzhou Huiju Chemical Co., Ltd.

Tel: 0371-55900031 18137872243
Fax: QQ：2853979815
Email: 2853979815@qq.com
Country: China
ProdList: 10010
Advantage: 55

Aikon International Limited

Tel: 025-66113011 18112977050
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 16027
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4824
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Fax: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 6756
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Abydos Scientific

Tel: 025-84767922 18936879710
Email: sales@abydoscientific.com
Country: China
ProdList: 1007
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Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd.

Tel: 13414494621
Fax: qq: 30307604
Email: chenchao02lzu@126.com
Country: China
ProdList: 122
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Jinan Carbotang Biotech Co.,Ltd.

Tel: +8615866703830
Email: figo.gao@foxmail.com
Country: China
ProdList: 8497
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32063
Advantage: 58

Hangzhou Huarong Pharm Co., Ltd.

Tel: 571-86758373 +8613588754946
Fax: 0086-571-81131109
Email: sales@huarongpharm.com
Country: CHINA
ProdList: 3148
Advantage: 58

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View Lastest Price from Mal-PEG4-Val-Cit-PAB-PNP manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-PEG4-Val-Cit-PAB-PNP 2112738-09-5
Price: US $0.00/mg
Min. Order: 100mg
Purity: >98.00%
Supply Ability: 100mg
Release date: 2024-03-29

2112738-09-5, Mal-PEG4-Val-Cit-PAB-PNPRelated Search:

Mal-PEG5-CH2CH2Mal Mal-PEG4-Val-Cit-PAB-OH 1-(14-Hydroxy-3,6,9,12-tetraoxatetradecyl)-1H-pyrrole-2,5-dione Mal-PEG4-amine TFA salt 1,1'-(3,6,9,12-tetraoxatetradecane-1,14-diyl)bis(1H-pyrrole-2,5-dione) Mal-PEG5-amine TFA salt

Mal-PEG4-Val-Cit-PAB-PNP

L-Ornithinamide, N-[15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-

4-((17S,20S)-1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosanamido)benzyl (4-nitrophenyl) carbonate

4-((17S,20S)-1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosan-21-amido)benzyl (4-nitrophenyl) carbonate

2112738-09-5

C40H53N7O15

Linker

ADC LINKER