ChemicalBook > CAS DataBase List > L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-
L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-
- Product Name
- L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-
- CAS No.
- 1948273-02-6
- Chemical Name
- L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-
- Synonyms
- (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide;VHL ligand 2;E3 ligase Ligand 1A;CPD101077;(S,R,S)-AHPC-Me;E3 ligase Ligand 1 (free base);L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-;VHL ligand-2,VHL ligand2,Inhibitor,inhibit,Ligands for E3 Ligase,(S,R,S) AHPC Me,(S,R,S)AHPCMe,E3 ligase-recruiting Moiety;(2S,4R)-1-[(S)-2-Amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[(S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]pyrrolidine-2-carboxamide;(2S,4S)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-h ydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phen yl]ethyl]pyrrolidine-2-carboxamide
- CBNumber
- CB23376069
- Molecular Formula
- C23H32N4O3S
- Formula Weight
- 444.59
- MOL File
- 1948273-02-6.mol
More
Less
L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- Property
- Boiling point:
- 687.9±55.0 °C(Predicted)
- Density
- 1.233±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 14.00±0.40(Predicted)
- InChIKey
- JOSFQWNOUSNZBP-UUZHKXTQSA-N
- SMILES
- C(N[C@H](C1=CC=C(C2SC=NC=2C)C=C1)C)(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](C(C)(C)C)N
More
Less
N-Bromosuccinimide Price
Biorbyt Ltd
- Product number
- orb611322
- Product name
- E3 ligase Ligand 1A
- Purity
- >98%
- Packaging
- 500mg
- Price
- $765
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611322
- Product name
- E3 ligase Ligand 1A
- Purity
- >98%
- Packaging
- 1g
- Price
- $1133.9
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611322
- Product name
- E3 ligase Ligand 1A
- Purity
- >98%
- Packaging
- 2g
- Price
- $1876.8
- Updated
- 2021/12/16
Ambeed
- Product number
- A351331
- Product name
- (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
- Purity
- 97%
- Packaging
- 1g
- Price
- $950
- Updated
- 2021/12/16
Ambeed
- Product number
- A351331
- Product name
- (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
- Purity
- 97%
- Packaging
- 50mg
- Price
- $142
- Updated
- 2021/12/16
More
Less
L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- Chemical Properties,Usage,Production
Description
E3 Ligase ligand 1a is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. E3 Ligase ligand 1a can be used to synthesize ARV-771, a BET PROTAC degrader.
Uses
(4R)-3-Methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-L-prolinamide, is a ligand of E3 ligase,
L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- Suppliers
- Tel
- 13504435624
- 1927928688@qq.com
- Country
- China
- ProdList
- 1350
- Advantage
- 58
- Tel
- 18344585702
- 550795326@qq.com
- Country
- China
- ProdList
- 74
- Advantage
- 58
- Tel
- 0431-80514535 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 5061
- Advantage
- 58
- Tel
- 0512-69561983 13914027025
- he_qf@medinoah.com
- Country
- China
- ProdList
- 3001
- Advantage
- 58
- Tel
- 17701559125
- jiaoshangjun@origsc.com
- Country
- China
- ProdList
- 1785
- Advantage
- 58
- Tel
- 18143011203
- ET-market@chemextension.com
- Country
- China
- ProdList
- 40885
- Advantage
- 58
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44700
- Advantage
- 61
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11660
- Advantage
- 64
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9452
- Advantage
- 58
- Tel
- 18149758185
- sales-cpd@caerulumpharma.com
- Country
- China
- ProdList
- 3423
- Advantage
- 58
- Tel
- 0431-80514535 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 4108
- Advantage
- 55
- Tel
- QQ:65489617 15618227136
- Fax
- 21-5161 9052
- info@SuperLan-chem.com
- Country
- China
- ProdList
- 9779
- Advantage
- 58
- Tel
- 13761310616
- Fax
- QQ: 39324283
- 39324283@qq.com
- Country
- China
- ProdList
- 1971
- Advantage
- 58
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28821
- Advantage
- 58
- Tel
- 0573-86-0573-85866609 13325730825
- Fax
- 0573-85866609
- 945717149@qq.com
- Country
- China
- ProdList
- 7960
- Advantage
- 58
- Tel
- 400-6387771-6039 18920564737
- sales@heowns.com
- Country
- China
- ProdList
- 20555
- Advantage
- 60
- Tel
- 0531-61320525 15866703830
- 495745175@qq.com
- Country
- China
- ProdList
- 6691
- Advantage
- 58
- Tel
- 0512-0512-69561983 13914027025
- Fax
- 0512-69561982
- he_qf@medinoah.com
- Country
- China
- ProdList
- 3445
- Advantage
- 58
- Tel
- +8615866703830
- figo.gao@foxmail.com
- Country
- China
- ProdList
- 7154
- Advantage
- 58
- Tel
- +8618530059196
- sale04@alfachem.cn
- Country
- China
- ProdList
- 12803
- Advantage
- 58
- Tel
- 021-58447131 13564518121
- sales@dcchemicals.com
- Country
- China
- ProdList
- 9414
- Advantage
- 58
- Tel
- 0371-55289822 18737195735
- Fax
- QQ:483339295
- 483339295@qq.com
- Country
- China
- ProdList
- 7089
- Advantage
- 58
- Tel
- 021-58461859 15821823057
- service@aiviche.com
- Country
- China
- ProdList
- 49323
- Advantage
- 58
- Tel
- 0371-0371-55135753 18003832934
- Fax
- QQ:2853979818
- 2853979818@qq.com
- Country
- China
- ProdList
- 9989
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing1@energy-chemical.com
- Country
- China
- ProdList
- 44843
- Advantage
- 58
- Tel
- +8613063595538
- donboo@donboo.com
- Country
- China
- ProdList
- 9365
- Advantage
- 58
- Tel
- 021-51816796-820 13611835272
- Fax
- 021-5161 3951
- sales2@sunwaypharm.com
- Country
- China
- ProdList
- 44486
- Advantage
- 58
- Tel
- 0755-85269922 13424394241
- Fax
- QQ:1799060443
- sales@shengdapharm.com
- Country
- China
- ProdList
- 506
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 39997
- Advantage
- 58
- Tel
- 400-168-9330 15013243073
- 597760450@qq.com
- Country
- China
- ProdList
- 2942
- Advantage
- 58
- Tel
- 400-1647117 15221909166
- product02@bidepharm.com
- Country
- China
- ProdList
- 63720
- Advantage
- 58
- Tel
- 13549236410
- sales@invivochem.cn
- Country
- China
- ProdList
- 6749
- Advantage
- 58
- Tel
- 13675144456
- alan.chow@synzest.com
- Country
- China
- ProdList
- 9471
- Advantage
- 58
- Tel
- 0574-27891269 18667892864
- frank.xiaodong@chemriotech.com
- Country
- China
- ProdList
- 3536
- Advantage
- 58
- Tel
- 2122619822
- czbjpharma@126.com
- Country
- China
- ProdList
- 18488
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24018
- Advantage
- 58
- Tel
- 021-50706066 15221275939
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 29803
- Advantage
- 58
- Tel
- 18621169109
- market03@meryer.com
- Country
- China
- ProdList
- 27996
- Advantage
- 58
- Tel
- 13621743886 13621743886
- 3366408901@qq.com
- Country
- China
- ProdList
- 3821
- Advantage
- 58
- Tel
- 13279368192 13279368192
- pharmaghs@126.com
- Country
- China
- ProdList
- 3443
- Advantage
- 58
- Tel
- 13854185395; 13854185395
- sanbaobiotech@126.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- 025-58851786 17714337195
- sales@tybiochem.com
- Country
- China
- ProdList
- 5141
- Advantage
- 58
- Tel
- 15638881523
- 68825546@qq.com
- Country
- China
- ProdList
- 2067
- Advantage
- 58
- Tel
- 15223382610 15223382610
- danny@chemdad.com
- Country
- China
- ProdList
- 1416
- Advantage
- 58
- Tel
- +undefined-21-51877795
- Fax
- +86 21 5161 9052/ 5187 7796
- ivan@atkchemical.com
- Country
- China
- ProdList
- 32686
- Advantage
- 60
- Tel
- +8618235132063
- sales@tihondan.com
- Country
- China
- ProdList
- 3725
- Advantage
- 58
- Tel
- +undefined18143011203
- info@chemextension.com
- Country
- China
- ProdList
- 42057
- Advantage
- 58
- Tel
- +8619950309693
- diane@biosynce.com
- Country
- China
- ProdList
- 4874
- Advantage
- 58
- Tel
- +86-512-68662322 +86-17312436797
- hanqun@origsc.com
- Country
- China
- ProdList
- 788
- Advantage
- 58
- Tel
- +86-852-30606658
- market18@leapchem.com
- Country
- China
- ProdList
- 43348
- Advantage
- 58
1948273-02-6, L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-Related Search:
E3 ligase Ligand 18
E3 ligase Ligand 10
E3 ligase Ligand 14
rac-((2R,3S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine
Cereblon Ligand 1
4-Hydroxy ThalidoMide
Protein degrader 1 (TFA)
(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione