ChemicalBook > CAS DataBase List > Olmesartan

Olmesartan

Product Name
Olmesartan
CAS No.
144689-24-7
Chemical Name
Olmesartan
Synonyms
Olmesartan Acid;CS 088;CS-415;RNH 6270;CS 088-d6;OMSTint-H;Olmesartan;Olmesartan EP Imp A;Olmesartan (RNH-6270;Olmesartan Olmesartan
CBNumber
CB2350011
Molecular Formula
C24H26N6O3
Formula Weight
446.5
MOL File
144689-24-7.mol
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Olmesartan Property

Melting point:
186-188°C
Boiling point:
738.3±70.0 °C(Predicted)
Density 
1.33
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
pka
2.39±0.50(Predicted)
form 
powder
color 
white to beige
Stability:
Hygroscopic
CAS DataBase Reference
144689-24-7(CAS DataBase Reference)
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Safety

RTECS 
NI4014100
HS Code 
29339900
Hazardous Substances Data
144689-24-7(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1394
Product name
Olmesartan
Purity
≥98% (HPLC)
Packaging
50MG
Price
$142
Updated
2023/06/20
TCI Chemical
Product number
O0507
Product name
Olmesartan
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$134
Updated
2024/03/01
Cayman Chemical
Product number
23412
Product name
Olmesartan
Purity
≥98%
Packaging
50mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
23412
Product name
Olmesartan
Purity
≥98%
Packaging
100mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
23412
Product name
Olmesartan
Purity
≥98%
Packaging
250mg
Price
$268
Updated
2024/03/01
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Olmesartan Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

An labelled angiotensin II receptor antagonist. Used as an anti-hypertensive

Uses

Angiotensin II inhibitor, antihypertensive

Uses

An angiotensin II (AT1) receptor antagonist

Uses

Olmesartan Acid (Olmesartan EP Impurity A) is an angiotensin II receptor antagonist. Used as an anti-hypertensive.

Definition

ChEBI: Olmesartan is a biphenylyltetrazole. It has a role as an antihypertensive agent and an angiotensin receptor antagonist.

General Description

Olmesartan medoxomil, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate (Benicar, Olmetec) uses the tetrazolering system as its acidic system, which participates inreceptor binding.When administered to a patient, the drugis rapidly and completely bioactivated by ester hydrolysis ofthe medoxomil during absorption from the gastrointestinaltract. Once the prodrug is converted to the active form, virtuallyno further metabolism occurs. In September 2007, theFood and Drug Administration (FDA) approved its use as acombination product with the calcium channel blocker amlodipinefor the management of hypertension. This combinationproduct is sold under the tradename of Azor.

Biochem/physiol Actions

Olmesartan possesses anti-inflammatory and anti-oxidative stress properties. It protects neuronal cells against oligomerized amyloid β (Aβ)-induced cellular senescence.

storage

Store at +4°C

Olmesartan Preparation Products And Raw materials

Raw materials

Preparation Products

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Olmesartan Suppliers

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View Lastest Price from Olmesartan manufacturers

Shanghai Yunao International Trade Co., Ltd
Product
Olmesartan 144689-24-7
Price
US $0.00/Kg
Min. Order
1KG
Purity
99%
Supply Ability
100ton
Release date
2021-04-22
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Product
Olmesartan 144689-24-7
Price
US $0.00/KG
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2020-11-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Olmesartan 144689-24-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

144689-24-7, OlmesartanRelated Search:

Propyl butyrate Isopropyl alcohol Hydroxyethyl Cellulose N,N-Diisopropylethylamine Dextromethorphan Ethyl maltol Propyl gallate Dextromethorphan hydrobromide monohydrate Olmesartan Medoxomil Biphenyl CHLOROPHOSPHONAZO III Levamisole 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-[(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid ethyl ester Olmesartan 4-CHLOROMETHYL-5-METHYL-1,3-DIOXOL-2-ONE (INTERMEDIATE OF OLMESARTAN MEDOXOMIL) Olmesartan intermediate 4-(1-Methoxy-1-methylethyl)-2-propyl-1H-Imidazole-5-carboxylic acid ethyl ester Diethyl 2-propylImidazoledicarbonate

  • 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid
  • Olmesartan
  • 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2’-(1H-tetazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid
  • CS 088
  • Olmesartan Acid
  • Olmesartan Medoxomil-1
  • CS-415
  • Olmesartan (Olmesartan Medoxomil EP Impurity A)
  • RNH 6270
  • CS 088-d6
  • OlMesartan (RNH6270, CS-088)
  • OlMesartan EP IMpurity A
  • 1H-IMidazole-5-carboxylicacid,4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-
  • (5-Methyl-2-oxo-1,3-dioxol-4-yl)Methyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl] 4-yl)Methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-iMidazole-5-carboxylate, 95+%
  • 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid
  • Olmesartan MedoxomiI Impurity A
  • Olmesartan EP Impurity A (Olmesartan Acid)
  • 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
  • 4-(2-Hydroxy-2-propanyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)-4-biphenylyl]methyl}-1H-imidazole-5-carboxylic acid
  • OMSTint-H
  • Olmesartan Solution, 1000ppm
  • Olmesartan Solution, 100ppm
  • Olmesartan Acid (Olmesartan EP Impurity A)
  • Olmesartan Medoxomil EP impurity A
  • Olmesartan Impurity 1(Olmesartan Medoxomil EP Impurity A)
  • Olmesartan Medoxomil EP Impurity A, RNH-6270
  • Olmesartan Olmesartan
  • 4-(1-Hydroxy-1-methylethyl)-2-propy
  • Olmesartan Acid (10mM in DMSO)
  • Olmesartan EP Imp A
  • Olmesartan (RNH-6270
  • 4-(2-Hydroxy-2-propanyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)-...
  • Azilsartan medoxomil impurity243
  • Olmesartan AcidQ: What is Olmesartan Acid Q: What is the CAS Number of Olmesartan Acid Q: What is the storage condition of Olmesartan Acid Q: What are the applications of Olmesartan Acid
  • Olmesartan Medoxomilum EP Impurity A
  • Olmesartan (Olmesartan Medoxomil EP
  • 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-1H-imidazole-5-carboxylic acid
  • Olmesartan ester impurity A
  • 1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid
  • 144689-24-7
  • 144698-24-7
  • C24H20D6N6O3
  • C24H26N6O3
  • Bases & Related Reagents
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals
  • Isotope Labeled Compounds