MATFPFPXUXCLHI-UHFFFAOYSA-N

Product Name: MATFPFPXUXCLHI-UHFFFAOYSA-N
CAS No.: 1639429-81-4
Chemical Name: MATFPFPXUXCLHI-UHFFFAOYSA-N
Synonyms: Ambrisentan Impurity 12;MATFPFPXUXCLHI-UHFFFAOYSA-N;Ambrisentan Vinyloxy Impurity;2-(2,2-Diphenylethenoxy)-4,6-dimethylpyrimidine;2-((2,2-Diphenylvinyl)oxy)-4,6-dimethylpyrimidine;4,6-dimethyl-2-(2,2-diphenyl-ethenyloxy)pyrimidine;Pyrimidine, 2-[(2,2-diphenylethenyl)oxy]-4,6-dimethyl-
CBNumber: CB23564383
Molecular Formula: C20H18N2O
Formula Weight: 302.37
MOL File: 1639429-81-4.mol

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MATFPFPXUXCLHI-UHFFFAOYSA-N Property

Melting point:: 94-96°C
Boiling point:: 464.1±55.0 °C(Predicted)
Density: 1.129±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 1.79±0.30(Predicted)
form: Solid
color: Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: D491645
Product name: 2-((2,2-Diphenylvinyl)oxy)-4,6-dimethylpyrimidine
Packaging: 250mg
Price: $1455
Updated: 2021/12/16

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MATFPFPXUXCLHI-UHFFFAOYSA-N Chemical Properties,Usage,Production

Uses

2-((2,2-Diphenylvinyl)oxy)-4,6-dimethylpyrimidine is an impurity of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.

MATFPFPXUXCLHI-UHFFFAOYSA-N Preparation Products And Raw materials

Raw materials

Preparation Products

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1639429-81-4, MATFPFPXUXCLHI-UHFFFAOYSA-NRelated Search:

(R)-AMbrisentan 2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3,3-diphenyl-2-propenoic Acid (S)-4-HydroxyMethyl AMbrisentan Benzenepropanoic acid,a-hydroxy-b-methoxy-b-phenyl-,(aS)- rac-Ambrisentan-d5 4,6-Dimethyl-2-hydroxypyrimidine Ambrisentan Ambrisentan pyrimidine Ester Impurity (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester Ambrisentan Hydroxy Acid Impurity (R-isomer) 4-Hydroxymethyl ambrisentan acyl beta-glucuronide Ambrisentan N-Oxide Ambrisentan Acyl Glucuronide (Mixture of Diastereomers) 4-Hydroxy Methyl Ambrisentan-D3

MATFPFPXUXCLHI-UHFFFAOYSA-N

2-((2,2-Diphenylvinyl)oxy)-4,6-dimethylpyrimidine

Ambrisentan Vinyloxy Impurity

4,6-dimethyl-2-(2,2-diphenyl-ethenyloxy)pyrimidine

Ambrisentan Impurity 12

Pyrimidine, 2-[(2,2-diphenylethenyl)oxy]-4,6-dimethyl-

2-(2,2-Diphenylethenoxy)-4,6-dimethylpyrimidine

1639429-81-4