ChemicalBook > CAS DataBase List > SPHINGOSYLPHOSPHORYLCHOLINE

SPHINGOSYLPHOSPHORYLCHOLINE

Product Name: SPHINGOSYLPHOSPHORYLCHOLINE
CAS No.: 1670-26-4
Chemical Name: SPHINGOSYLPHOSPHORYLCHOLINE
Synonyms: SPC;MGC119002;D-ERYTHRO-SPC;Lyso SM (d18:1);LYSO-SPHINGOMYELIN;urocortin 3 (stresscopin);Lyso-Sphingomyelin (d18:1);SPHINGOSYLPHOSPHORYLCHOLINE;spingosyl-phosphorylcholine;Sphingenyl-1-phosphorylcholine
CBNumber: CB2356664
Molecular Formula: C23H49N2O5P
Formula Weight: 464.62
MOL File: 1670-26-4.mol

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SPHINGOSYLPHOSPHORYLCHOLINE Property

Melting point:: 90-102°C
storage temp.: -20°C
solubility: chloroform/methanol (2:1): complete10 mg/ml, clear to slightly hazy, colorless to light yellow
form: powder
color: light yellow
biological source: goat
BRN: 7342520

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Safety

WGK Germany: 3
F: 1-8-10

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SAB2501823
Product name: Anti-UCN3 antibody produced in goat
Purity: affinity isolated antibody, buffered aqueous solution
Packaging: 100 μg
Price: $586
Updated: 2025/07/31

Cayman Chemical

Product number: 10007947
Product name: Lyso-Sphingomyelin (d18:1)
Purity: ≥98%
Packaging: 1mg
Price: $90
Updated: 2024/03/01

Cayman Chemical

Product number: 10007947
Product name: Lyso-Sphingomyelin (d18:1)
Purity: ≥98%
Packaging: 5mg
Price: $401
Updated: 2024/03/01

Sigma-Aldrich

Product number: S4257
Product name: Sphingosylphosphoryl-choline
Purity: ≥98%, powder
Packaging: 10mg
Price: $341
Updated: 2025/07/31

Sigma-Aldrich

Product number: S4257
Product name: Sphingosylphosphoryl-choline
Purity: ≥98%, powder
Packaging: 25mg
Price: $811
Updated: 2025/07/31

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SPHINGOSYLPHOSPHORYLCHOLINE Chemical Properties,Usage,Production

Chemical Properties

Yellowish Waxy Solid

Uses

Involved in cell regulation, and transmembrane signaling. A putative lipid second messenger, connected via Protein Kinase C to the phosphatidylinositol-derived second messengers for signal transduction.

Uses

Neurotrophic effects of Sphingosylphosphorylcholine were studied in cerebellar granule neurons of mice and PC-12 cells.

Uses

Lyso SM (d18:1) has been used:

to study its effect on the skeletal muscle ryanodine receptor (RyR1), in the presence and absence of calmodulin through single channel recordings in planar lipid bilayers
as an inhibitor of Ca²⁺sensor calmodulin (CaM)
as a standard in circular dichroism (CD) spectroscopy to determine lipid selectivity of the lipid-peptide interactions

Definition

ChEBI: Sphingosine-1-phosphocholine is a phosphosphingolipid consisting of sphingosine having a phosphocholine moiety attached to its primary hydroxyl group. It is a phosphosphingolipid, a member of phosphocholines and an ammonium betaine. It is functionally related to a sphingosine. It is a conjugate base of a sphingosylphosphocholine acid and a sphingosine-1-phosphocholine(1+).

General Description

Lyso SM (d18:1), also known as sphingosylphosphorylcholine (SPC), is a bioactive lipid molecule. This lysophospholipid is present in normal blood plasma, ascites and various tissues.

Biochem/physiol Actions

Sphingosylphosphorylcholine (SPC) is a bioactive lipid that mediates intracellular and extracellular signaling. It mobilizes Ca2+ from intracellular stores via an IP3-independent pathway. It stimulates the production of CCL2 that may contribute to development of atherosclerosis. SPC is a ligand for endothelial differentiation gene receptor 3 (EDG3).

SPHINGOSYLPHOSPHORYLCHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from SPHINGOSYLPHOSPHORYLCHOLINE manufacturers

Career Henan Chemical Co

Product: SPHINGOSYLPHOSPHORYLCHOLINE 1670-26-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%-99.9%
Supply Ability: 200kg
Release date: 2020-01-10

1670-26-4, SPHINGOSYLPHOSPHORYLCHOLINERelated Search:

LYSO-SPHINGOMYELIN

D-ERYTHRO-SPC

D-ERYTHRO-SPHINGOSYLPHOSPHORYLCHOLINE

SPHINGOSYLPHOSPHORYLCHOLINE

SPHINGOSYLPHOSPHORYLCHOLINE, D-ERYTHRO

Sphingosylphosphoryl-choline - CAS 1670-26-4 - Calbiochem

2-[[[(2-amino-3-hydroxy-4-octadecenyl)oxy]hydroxy-phosphinyl]oxy]-n,n,n-trimethylethanaminium inner salt

(2S,3R,4E)-2-Amino-4-octadecene-3-hydroxy-1-phosphocholine

D-erythro-Sphingosine phosphocholine

Lyso SM (d18:1)

Anti-UCN3 antibody produced in goat

MGC119002

urocortin 3 (stresscopin)

SPHINGOSYLPHOSPHORYLCHOLINE;LYSO SM (D18:1)

Lyso-Sphingomyelin (d18:1)

D-erythro-Sphingosylphosphorylcholine (Synthetic)

2-[[[[(2S,3R,4E)-2-AMino-3-hydroxy-4-octadecen-1-yl]oxy]hydroxyphosphinyl]oxy]-N,N,N-triMethyl-ethanaMiniuM

Sphingenyl-1-phosphorylcholine

spingosyl-phosphorylcholine

Lysosphingomyelin, 2-[[[(2-Amino-3-hydroxy-4-octadecenyl)oxy]hydroxy-phosphinyl]oxy]-N,N,N-trimethylethanaminium inner salt

SPC

D-erythro Lysosphingomyelin (d18:1)

1670-26-4

C23H49N2O5P

Lipids

Phosphosphingolipids

Sphingolipids

Ceramide phosphocholines (sphingomyelins)

BioChemical

Biochemicals and Reagents

Activators

Fatty Acid Derivatives & Lipids

Glycerols

Inhibitors

Protein Kinase Inhibitors and Activators

Chemical Activators