2,4,6-Tri-tert-butylphenol
- Product Name
- 2,4,6-Tri-tert-butylphenol
- CAS No.
- 732-26-3
- Chemical Name
- 2,4,6-Tri-tert-butylphenol
- Synonyms
- 2,4,6-Tris(tert-butyl)phenol;Phenol, 2,4,6-tri-tert-butyl-;P23;Phenol,2,4,6-tri-tert-butyl-;P 23;TM02;CRYA2;NCK5A;Voidox;CDK5P35
- CBNumber
- CB2357818
- Molecular Formula
- C18H30O
- Formula Weight
- 262.43
- MOL File
- 732-26-3.mol
2,4,6-Tri-tert-butylphenol Property
- Melting point:
- 125-130 °C (lit.)
- Boiling point:
- 277 °C (lit.)
- Density
- 0.8640
- vapor pressure
- 0.073Pa at 25℃
- refractive index
- 1.5029 (estimate)
- Flash point:
- 130 °C
- storage temp.
- -70°C
- solubility
- Chloroform (Slightly), DMSO (Slightly, Sonicated)
- pka
- 12.61±0.40(Predicted)
- form
- buffered aqueous glycerol solution
- color
- Off-White to Pale Yellow
- Water Solubility
- insoluble
- BRN
- 1913256
- InChIKey
- PFEFOYRSMXVNEL-UHFFFAOYSA-N
- LogP
- 7.1 at 35℃
- CAS DataBase Reference
- 732-26-3(CAS DataBase Reference)
- NIST Chemistry Reference
- Phenol, 2,4,6-tris(1,1-dimethylethyl)-(732-26-3)
- EPA Substance Registry System
- 2,4,6-Tris(tert-butyl)phenol (732-26-3)
Safety
- Hazard Codes
- F,C,N,Xi,Xn
- Risk Statements
- 11-22-34-50-53-36/37/38-51/53
- Safety Statements
- 26-36/37/39-45-60-61-24/25
- RIDADR
- UN 2430 8/PG 3
- WGK Germany
- 3
- RTECS
- SN3570000
- F
- 8-23
- HazardClass
- 9
- PackingGroup
- III
- HS Code
- 29071990
- Hazardous Substances Data
- 732-26-3(Hazardous Substances Data)
- Toxicity
- LD50 oral in rat: 1670mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
H373May cause damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- T49409
- Product name
- 2,4,6-Tri-tert-butylphenol
- Purity
- 98%
- Packaging
- 100g
- Price
- $126
- Updated
- 2024/03/01
- Product number
- SAB4500484
- Product name
- Anti-CRYAB antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μG
- Price
- $506
- Updated
- 2024/03/01
- Product number
- C0745
- Product name
- CDK5/p25, active, GST tagged human
- Purity
- PRECISIO? Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
- Packaging
- 10μG
- Price
- $525
- Updated
- 2023/06/20
- Product number
- SAB4500486
- Product name
- Anti-CRYAB antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μG
- Price
- $485
- Updated
- 2023/01/07
- Product number
- CHM0007865
- Product name
- 2,4,6-TRI-TERT-BUTYLPHENOL
- Purity
- 95.00%
- Packaging
- 100G
- Price
- $2501.06
- Updated
- 2021/12/16
2,4,6-Tri-tert-butylphenol Chemical Properties,Usage,Production
Chemical Properties
Solid. Insoluble in water; soluble in most organic solvents. Combustible.
Uses
2,4,6-Tri-tert-butylphenol is an antioxidant; used in preparation method of high-temperature resistant electromagnetic shielding electromagnetic bushing.
Flammability and Explosibility
Non flammable
Purification Methods
Distil the phenol under reduced pressure and/or recrystallise it from n-hexane or several times from 95% EtOH until the EtOH solution is colourless [Balasubramanian & Bruice J Am Chem Soc 108 5495 1986]. It has also been purified by sublimation [Yuan & Bruice J Am Chem Soc 108 1643 1986, Wong et al. J Am Chem Soc 109 3428 1987]. Purification has also been achieved by passage through a silica gel column followed by recrystallisation from n-hexane [Kajii et al. J Phys Chem 91 2791 1987]. [Beilstein 6 III 2094, 6 IV 3539.]
Toxicity evaluation
In order to study the chronic toxicity of 2,4,6-tri-tert-butylphenol (TTBP), groups of 40 Slc: Wistar rats of either sex were fed a diet containing 0, 30, 100, 300, or 1000 ppm of TTBP for up to 24 months. Hematological, biochemical, and histopathological examinations performed periodically revealed slight microcytic anemia, changes in some biochemical parameters relating to liver function, and focal necrosis of liver cells following TTBP administration, and these changes observed in females were more severe than those in males. No neoplastic responses following TTBP administration were noted. Hence, it was concluded that TTBP causes liver injury characterized by focal necrosis with microcytic anemia and elevations of serum phospholipids and cholesterol levels, presumably occurring as secondary effects following the liver injury[1].
References
[1] Matsumoto, Kiyoshi , et al. "Chronic toxicity of 2,4,6-tri-tert-butylphenol in rats." Journal of Toxicological Sciences 16.4(1991):167.
2,4,6-Tri-tert-butylphenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,4,6-Tri-tert-butylphenol manufacturers
- Product
- 2,4,6-Tri-tert-butylphenol 732-26-3
- Price
- US $75.00-20.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-06-07
- Product
- 2,4,6-Tri-tert-butylphenol 732-26-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-01
- Product
- 2,4,6-Tri-tert-butylphenol 732-26-3
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-09-23