1-INDOLEPROPIONIC ACID
- Product Name
- 1-INDOLEPROPIONIC ACID
- CAS No.
- 6639-06-1
- Chemical Name
- 1-INDOLEPROPIONIC ACID
- Synonyms
- 1-INDOLEPROPIONIC ACID;Indole-1-propionic acid;B-N-INDOLEPROPIONIC ACID;1H-indole-1-propanoic acid;3-indol-1-ylpropionic acid;3-indol-1-ylpropanoic acid;3-(1-indolyl)propanoic acid;BETA-N-INDOLE PROPIONIC ACID;3-(1H-INDOL-1-YL)PROPANOIC ACID
- CBNumber
- CB2379252
- Molecular Formula
- C11H11NO2
- Formula Weight
- 189.21
- MOL File
- 6639-06-1.mol
1-INDOLEPROPIONIC ACID Property
- Melting point:
- 91 °C
- Boiling point:
- 180-197 °C
- Density
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.59±0.10(Predicted)
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- S540390
- Product name
- 1-INDOLEPROPIONIC ACID
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $185
- Updated
- 2025/07/31
- Product number
- S540390
- Product name
- 1-INDOLEPROPIONIC ACID
- Purity
- AldrichCPR
- Packaging
- 1G
- Price
- $179
- Updated
- 2024/03/01
- Product number
- Z5006
- Product name
- 3-(1H-Indol-1-yl)propanoicacid
- Packaging
- 10g
- Price
- $611
- Updated
- 2021/12/16
- Product number
- CHM0118689
- Product name
- 1-INDOLEPROPIONIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $648.81
- Updated
- 2021/12/16
- Product number
- CHM0118689
- Product name
- 1-INDOLEPROPIONIC ACID
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $852.21
- Updated
- 2021/12/16
1-INDOLEPROPIONIC ACID Chemical Properties,Usage,Production
Synthesis
120-72-9
3395-91-3
6639-06-1
General procedure for the synthesis of 1-indolepropionic acid from indole and methyl 3-bromopropionate: Synthesis of 3-(1H-indol-1-yl)propionic acid (Intermediate-25): 10 mL of DMF was added to a 100 mL round bottom flask fitted with a magnetic stirrer. to the stirred solvent was added indole (1.0 g, 8.53 mmol) followed by sodium hydride (400 mg, 10.24 mmol). The resulting mixture was stirred at room temperature for 1 hr. Methyl 3-bromopropionate (2.13 g, 12.79 mmol) was added to the above reaction solution and stirring was continued for 24 hours at room temperature. After completion of the reaction (the progress of the reaction was monitored by TLC), the reaction mixture was diluted with 30 mL of ice water and washed with ether. The aqueous phase was acidified with 1N HCl to pH=2 and subsequently extracted with EtOAc and concentrated to give Intermediate-24 (900 mg).
References
[1] Patent: WO2013/128465, 2013, A1. Location in patent: Page/Page column 94
[2] Patent: US2015/158860, 2015, A1. Location in patent: Paragraph 0332
[3] Patent: WO2004/43899, 2004, A1. Location in patent: Page 37; 38
1-INDOLEPROPIONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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