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TALAMPICILLIN

Product Name
TALAMPICILLIN
CAS No.
47747-56-8
Chemical Name
TALAMPICILLIN
Synonyms
C11751;TALAMPICILLIN;TALAMPICILLIN USP/EP/BP;Ampicillin phthalidyl ester;3-Phthalidyl D-2-amino-2-phenylacetamidopenicillanic acid;(6R)-6-[[(R)-2-Amino-2-phenylacetyl]amino]penicillanic acid 1,3-dihydro-3-oxoisobenzofuran-1-yl ester;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, [2S-[2a,5a,6b(S*)]]-;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, (2S,5R,6R)-;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, (2S,5R,6R)- (9CI)
CBNumber
CB2403465
Molecular Formula
C24H23N3O6S
Formula Weight
481.52
MOL File
47747-56-8.mol
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TALAMPICILLIN Property

Boiling point:
770.9±60.0 °C(Predicted)
Density 
1.48±0.1 g/cm3(Predicted)
pka
12.15±0.60(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0012556
Product name
TALAMPICILLIN
Purity
95.00%
Packaging
5MG
Price
$501.44
Updated
2021/12/16
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TALAMPICILLIN Chemical Properties,Usage,Production

Originator

Talpen,Beecham,US,1975

Uses

Antibacterial.

Definition

ChEBI: Talampicillin is a penicillanic acid ester that is the 1-phthalidyl ester of ampicillin. It is a prodrug of ampicillin. It has a role as a prodrug. It is functionally related to an ampicillin and an o-phthalaldehydic acid.

Manufacturing Process

A fine suspension of 25.18 grams (0.05 mol) of potassium salt of enamine protected ampicillin and 10.65 grams (0.05 mol) 3-bromophthalide were reacted in a 1:2 mixture of acetone/ethyl acetate (1,500 ml) for 24 hours. After filtration the organic layer was washed twice with 250 ml portions of 1 N sodium bicarbonate and brine, dried over anhydrous magnesium sulfate and concentrated in vacuo. Addition of ether crystallized the phthalide enamine protected α-aminophenylacetamido penicillanate in 85% yield.

Therapeutic Function

Antibacterial

TALAMPICILLIN Preparation Products And Raw materials

Raw materials

Preparation Products

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TALAMPICILLIN Suppliers

China 6 Germany 1 India 2 United Kingdom 2 United States 5 Global 16
Leancare Ltd.
Tel
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Fax
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Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
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CARBONE SCIENTIFIC CO.,LTD
Tel
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Fax
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Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
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47747-56-8, TALAMPICILLINRelated Search:

TALAMPICILLIN HYDROCHLORIDE EPT(CRM STANDARD) TALAMPICILLIN HYDROCHLORIDE 3-Methoxy-1(3H)-isobenzofuranone 4-METHOXY-2-METHYL-2-BUTANETHIOL PENAMECILLIN D-Talampicillin hydrochloride TALAMPICILLIN ETHYL 3-(METHYLTHIO)BUTYRATE

  • 3-Phthalidyl D-2-amino-2-phenylacetamidopenicillanic acid
  • TALAMPICILLIN
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, [2S-[2a,5a,6b(S*)]]-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, (2S,5R,6R)- (9CI)
  • Ampicillin phthalidyl ester
  • (6R)-6-[[(R)-2-Amino-2-phenylacetyl]amino]penicillanic acid 1,3-dihydro-3-oxoisobenzofuran-1-yl ester
  • C11751
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, (2S,5R,6R)-
  • TALAMPICILLIN USP/EP/BP
  • 47747-56-8
  • C24H23N3O6S