(4-Carboxybutyl)triphenylphosphonium bromide

Product Name: (4-Carboxybutyl)triphenylphosphonium bromide
CAS No.: 17814-85-6
Chemical Name: (4-Carboxybutyl)triphenylphosphonium bromide
Synonyms: CBT;NSC 147756;(4-Carboxybut;(4-CarboxybutyL;Latanoprost Impurity 20;Alprostadil Impurity 17;Rivastigmine Impurity 58;Tafluprost Impurity 9 Bromide;(4-Carboxybutyl)triphenylphosp;4-carboxybutyl(triphenyl)phosphanium
CBNumber: CB2407120
Molecular Formula: C23H24BrO2P
Formula Weight: 443.31
MOL File: 17814-85-6.mol

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(4-Carboxybutyl)triphenylphosphonium bromide Property

Melting point:: 204-207 °C(lit.)
Boiling point:: 324.7-327.4℃ at 101.93-102.15kPa
bulk density: 360-400kg/m3
Density: 1.371 at 20℃
vapor pressure: 0Pa at 25℃
Flash point:: 195°(383°F)
storage temp.: Store below +30°C.
solubility: DMSO, Methanol, Water
form: solid
color: White to Off-White
Water Solubility: Soluble in ethanol, methanol and soluble water. Insoluble in toluene and hexane.
Sensitive: Hygroscopic
BRN: 3586477
InChIKey: KQJPHSBFOSLICV-UHFFFAOYSA-N
LogP: 0.146
CAS DataBase Reference: 17814-85-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: 3278
WGK Germany: 3
HS Code: 29310095

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.18330
Product name: 4-Carboxybutyltriphenylphosphonium bromide
Purity: for synthesis
Packaging: 50g
Price: $92.4
Updated: 2025/07/31

Sigma-Aldrich

Product number: 157945
Product name: (4-Carboxybutyl)triphenylphosphonium bromide
Purity: 98%
Packaging: 50g
Price: $154
Updated: 2025/07/31

Sigma-Aldrich

Product number: 157945
Product name: (4-Carboxybutyl)triphenylphosphonium bromide
Purity: 98%
Packaging: 250g
Price: $344
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.45134
Product name: 4-Carboxybutyltriphenylphosphonium bromide
Purity: Msynth?plus
Packaging: 50g
Price: $119
Updated: 2022/05/15

Sigma-Aldrich

Product number: 8.45134
Product name: 4-Carboxybutyltriphenylphosphonium bromide
Purity: Msynth?plus
Packaging: 1kg
Price: $1650
Updated: 2022/05/15

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(4-Carboxybutyl)triphenylphosphonium bromide Chemical Properties,Usage,Production

Chemical Properties

WHITE TO ALMOST WHITE CRYSTALLINE POWDER

Uses

suzuki reaction

Uses

(4-Carboxybutyl)triphenylphosphonium Bromide (cas# 17814-85-6) is a compound useful in organic synthesis.

Uses

Used as a platform for delivery of pro-apoptotic peptides into the mitochondria of tumor cells

Reactant for preparation of:

Ring skeletons via ring closing metathesis and double bond migration ring closing metathesis reactions
Methyl alkenyl quinolones as antimycobacterial agents
Prostaglandins and their drug analogs via Gold-catalyzed Meyer-Schuster rearrangement
Diphenylmethylpiperazines as N-type calcium channel blockers as potential therapeutic agents
Folate receptor-specific glycinamide ribonucleotide formyltransferase (GARFTase) inhibitors with antitumor activity
Cycloalkylidene alkanols with antileishmanial activity, via Wittig reaction

reaction suitability

reaction type: C-C Bond Formation

Synthesis

2067-33-6

603-35-0

17814-85-6

General method: 5-Bromovaleric acid (1 eq.) and triphenylphosphine (1 eq.) were dissolved in 300 mL of toluene and the reaction was refluxed under argon protection for 48 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under reduced pressure. The target product 4-carboxybutyltriphenylphosphonium bromide was obtained by crystallization and purification of the residue from a suitable solvent.

References

[1] Journal of Organic Chemistry, 1999, vol. 64, # 9, p. 3196 - 3206
[2] Canadian Journal of Chemistry, 2003, vol. 81, # 6, p. 697 - 704
[3] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 1, p. 567 - 579
[4] Journal of Organic Chemistry, 1987, vol. 52, # 20, p. 4449 - 4453
[5] Journal of Medicinal Chemistry, 2017, vol. 60, # 14, p. 6353 - 6363

(4-Carboxybutyl)triphenylphosphonium bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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(4-Carboxybutyl)triphenylphosphonium bromide Suppliers

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View Lastest Price from (4-Carboxybutyl)triphenylphosphonium bromide manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: (4-Carboxybutyl)triphenylphosphonium bromide 17814-85-6
Price: US $1.00-4.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2025-09-11

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: (4-Carboxybutyl)triphenylphosphonium bromide 17814-85-6
Price: US $50.00-10.00/kg
Min. Order: 1kg
Purity: 99%，Electronic grade(Single metal impurity≤ 100ppb) or pharmaceutical grade
Supply Ability: 1000kg
Release date: 2025-07-17

Watson Biotechnology Co.,Ltd

Product: (4-Carboxybutyl)triphenylphosphonium bromide 17814-85-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 20MT
Release date: 2025-07-14

17814-85-6, (4-Carboxybutyl)triphenylphosphonium bromideRelated Search:

DICHLOROTRIPHENYLPHOSPHORANE Tetraphenylphosphonium bromide Allyl bromide Sodium bromate Tetrabutylammonium bromide Rocuronium bromide Ethidium bromide Triphenylphosphine hydrobromide Benzyltributylammonium bromide Methyltriphenylphosphonium bromide Ethyltriphenylphosphonium bromide Phenylmagnesium bromide Methyl bromide Butyltriphenylphosphonium bromide DIPHENYL-N-PROPYLPHOSPHINE (4-ETHOXYCARBONYLBUTYL)TRIPHENYLPHOSPHONIUM BROMIDE Triphenyl(propyl)phosphonium bromide BUTYLDIPHENYLPHOSPHINE

(4-CARBOXYBUTYL)TRIPHENYLPHOSPHONIUM BROMIDE

(4-Carboxybutyl)triphenylphosp

PhosphoniuM,(4-carboxybutyl)triphenyl-, broMide (1:1)

4-carboxybutyltripheyl phosphonium bromide

(4-(4-carboxybutyl)phenyl)diphenylphosphonium bromide

4-carboxybutyl(triphenyl)phosphanium,bromide

(4-Carboxybut

(4-Carboxybut-1-yl)(triphenyl)phosphonium bromide 98%

CBT

(4-carboxybutyl)triphenyl-phosphoniubromide

Phosphonium, (4-carboxybutyl)triphenyl-, bromide

4-CARBOXYBUTYLTRIPHENYLPHOSPHONIUM BROMIDE 98%

(4-Carboxybutyl)triphenylphosphonium bromide, 98 %

(5-Hydroxy-5-oxopentyl)-triphenylphosphanium bromide

5-(Triphenylphosphonio)pentanoic Acid BroMide

CarboxybutyltriphenylphosphoniuM BroMide

NSC 147756

Triphenyl(4-carboxybutyl)phosphoniuM BroMide

4-CARBOXYBUTYLTRIPHENYLPHOSPHONIUM BROMI

(4-Carboxybutyl)triphenylphosponiuM broMide

(4-Carboxybutyl)-triphenylphosphoMuM broMide

(4-Carboxybutyl) triphenylphosphoniuM briMide

4-(Carboxybutyl)triphenylphosphonium Bromide &gt

4-CARBOXY-BUT-3PHEN-PHOS-BR MSYNTH PLUS

(4-CarboxybutyL

Benzenemethanol, ?-(aminomethyl)-2,5-dimethoxy- hydrochloride

4-carboxybutyl(triphenyl)phosphanium

Latanoprost Impurity 20

Rivastigmine Impurity 58

Tafluprost Impurity 9 Bromide

Alprostadil Impurity 17

(4-Carboxybut-1-yl)(triphenyl)phosphonium bromide

4-carbonylbutoxy triphenyl bromophosphine

4-carboxybutyl triphenyl bromophosphine

17814-85-6

C23H25BrO2P

C6H53PBrCH24COOH

HO2CCH24PC6H53Br

C23H24BrO2P

C23H24O2PBr

Phosphonium Compounds

Wittig & Horner-Emmons Reaction

Wittig Reaction

Olefination

Wittig Reagents

Synthetic Reagents

C-C Bond Formation

Miscellaneous Reagents

API intermediates

Miscellaneous Compounds

Phosphonium Compounds

Synthetic Organic Chemistry

Wittig & Horner-Emmons Reaction

Wittig Reaction

C-C Bond Formation

Olefination

Wittig Reagents