ChemicalBook > CAS DataBase List > D(-)-Arginine

D(-)-Arginine

Product Name
D(-)-Arginine
CAS No.
157-06-2
Chemical Name
D(-)-Arginine
Synonyms
D-ARGININE;H-D-ARG-OH;D-ARG;D-Arg-OH;D-Arginin;H-D-Arginine;ARGININE, D-;D-(-)-ARGININE;R-(-)-ARGININE;D-Arginine，98%
CBNumber
CB2408147
Molecular Formula
C6H14N4O2
Formula Weight
174.2
MOL File
157-06-2.mol
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D(-)-Arginine Property

Melting point:
226 °C (dec.) (lit.)
alpha 
-28.5 º (c=8, 6 N HCl)
Boiling point:
305.18°C (rough estimate)
Density 
1.2297 (rough estimate)
refractive index 
-23 ° (C=8, 6mol/L HCl)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Aqueous Acid (Slightly), Water (Slightly)
form 
Solid
pka
2.49±0.24(Predicted)
color 
White to Off-White
Water Solubility 
SOLUBLE
Sensitive 
Air Sensitive
BRN 
1725412
InChIKey
ODKSFYDXXFIFQN-SCSAIBSYSA-N
LogP
-0.999 (est)
CAS DataBase Reference
157-06-2(CAS DataBase Reference)
EPA Substance Registry System
D-Arginine (157-06-2)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36-36/37/38-20/21/22
Safety Statements 
26-36
WGK Germany 
3
RTECS 
CF1934220
F 
9
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29252000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A2646
Product name
D-Arginine
Purity
≥98% (TLC)
Packaging
1g
Price
$106
Updated
2024/03/01
Sigma-Aldrich
Product number
A2646
Product name
D-Arginine
Purity
≥98% (TLC)
Packaging
5g
Price
$364
Updated
2024/03/01
TCI Chemical
Product number
A1029
Product name
D-(-)-Arginine
Purity
>98.0%(T)
Packaging
1g
Price
$57
Updated
2024/03/01
TCI Chemical
Product number
A1029
Product name
D-(-)-Arginine
Purity
>98.0%(T)
Packaging
5g
Price
$196
Updated
2024/03/01
Alfa Aesar
Product number
A16137
Product name
D-Arginine, 98%
Packaging
1g
Price
$61.65
Updated
2024/03/01
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D(-)-Arginine Chemical Properties,Usage,Production

Description

D-arginine is the D-form of arginine, which is a kind of amino acids. It can be reacted with hydrogen peroxide for non-enzymatic synthesis of nitric oxide. It has certain pharmacological activities. For example, its derivative, 1-deamino-8-D-arginine vasopressin is useful for the management of haemophilia and von Willebrand’s disease. It also has the potential to inhibit the proliferation of certain cancer cells. In biological research, D-arginine is frequently used in the studies of L-arginine/nitric oxide pathway as an inactive form of L-arginine.

Chemical Properties

white to light yellow crystal powde

Uses

Arginine is an essential amino acid found in food and plant sources, and many biological systems.
D-Arginine is extensively used in studies on L-arginine/nitric oxide pathway as an inactive form of L-arginine, even in man.
D-Arginine is slightly soluble (in water) and a moderately acidic compound (based on its pKa). D-Arginine can be found in human epidermis and platelet tissues. Within the cell, D-arginine is primarily located in the peroxisome. D-Arginine specifically can inhibit arginine decarboxylase enzymes and also functions as a metabolite.

Uses

1-Deamino-8-D-arginine vasopressin makes a new pharmacological approach to the management of haemophilia and von Willebrand's disease. A novel nonenzymatic pathway for the generation of nitric oxide is by the reaction of hydrogen peroxide and d- or l-arginine.

Definition

ChEBI: A D-alpha-amino acid that is the D-isomer of arginine.

References

https://www.alfa.com/zh-cn/catalog/A16137/
Iannucci, N. B., et al. "Antiproliferative effect of 1-deamino-8-D-arginine vasopressin analogs on human breast cancer cells." Future Medicinal Chemistry 3.16(2011):1987-1993.
Ripoll, Giselle, et al. "Angiostatic activity of 1-Deamino-8-D-Arginine vasopressin and novel peptide analogues in breast cancer cells." Cancer Research 68(2008).
Navarro, Eduardo, et al. "Toxicological and Pharmacological Effects of D-Arginine." Basic & Clinical Pharmacology & Toxicology97.3(2005):149-154.

D(-)-Arginine Preparation Products And Raw materials

Raw materials

O-methylisourea D-Ornithine monohydrochloride

Preparation Products

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D(-)-Arginine Suppliers

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View Lastest Price from D(-)-Arginine manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
D(-)-Arginine 157-06-2
Price
US $100.00-75.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-22
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
D(-)-Arginine 157-06-2
Price
US $999.00-800.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-22
WUHAN FORTUNA CHEMICAL CO., LTD
Product
D(-)-Arginine 157-06-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%min
Supply Ability
500kg
Release date
2024-06-03

157-06-2, D(-)-ArginineRelated Search:

L(+)-Arginine EPA Guanidineacetic acid Glycine 3-Guanidinopropionic acid ARGINASE 6-Aminocaproic acid ALTRENOGEST 5-Amino-2-methylpyridine D-Lysine H-D-CIT-OH D-Ornithine monohydrochloride D-Ribose Arginine arginine aspirin BOC-D-Arg(Tos)-OH D-(-)-Arginine hydrochloride N-Fmoc-N'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-D-arginine

  • (2R)-2-ammonio-5-(diaminomethylideneammonio)pentanoate
  • R-(-)-ARGININE
  • (R)-2-AMINO-5-GUANIDINOPENTANOIC ACID
  • RARECHEM AB PP 1748
  • D-ARG
  • D-(-)-ARGININE
  • D-ARGININE
  • D-2-AMINO-5-GUANIDINOVALERIC ACID
  • H-D-Arginine
  • (-)-D-arginine hydrate
  • D-ARGININE FREE BASE
  • d-2-amino-5-guanidinopentanoic acid
  • (2R)-2-amino-5-(diaminomethylideneamino)pentanoic acid
  • ARGININE, D-(RG)
  • ARGININE, D-
  • H-D-ARG-OH
  • D-ARG.FREE BASE
  • D-ARGININE BASE
  • (2R)-2-Amino-5-(diaminomethylideneamino)pentanoic acid hydrate
  • D-Arginine ,99%
  • D-Arginine,(R)-2-Amino-5-guanidinopentanoic acid
  • D-GuanidineaMinovaleric acid
  • D-α-AMino-δ-guanidovaleric acid
  • D-Arg-OH
  • H-D-Arg-OH (R)-2-Amino-5-guanidinopentanoic acid D-2-Amino-5-guanidinovaleric acid
  • D-Arginine,99%e.e.
  • (2R)-2-amino-5-carbamimidamidopentanoic acid
  • D-Arginin
  • Arginine Impurity 5（D-Arginine）
  • D-(-)-Arginine &gt
  • D-Arginine, 99%, reagent grade
  • D-Arginine，98%
  • D(-)-Arginine USP/EP/BP
  • D- arginine base USP/EP/BP
  • dextro-arginine
  • TIANFU-CHEM D(-)-Arginine
  • D-Arginine (free base) extrapure CHR, 99%
  • (2R)-2-amino-5-guanidino-pentanoic acid
  • 157-06-2
  • C6H14N4O2
  • for Resolution of Acids
  • Optical Resolution
  • Amino Acid Derivatives
  • Specialty Synthesis
  • Peptide Synthesis
  • amino
  • Amino Acids
  • Arginine [Arg, R]
  • Amino Acids and Derivatives
  • alpha-Amino Acids
  • Amino Acids
  • Biochemistry
  • for Resolution of Acids
  • Optical Resolution
  • Synthetic Organic Chemistry
  • PROTECTED AMINO ACID & PEPTIDES
  • Amino Acids Derivatives
  • chiral