ChemicalBook > CAS DataBase List > 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate

2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate

Product Name: 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate
CAS No.: 101385-69-7
Chemical Name: 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate
Synonyms: CIP;2-CHLORO-1,3-DIMETHYLIMIDAZOLINIUM HEXAFLUOROPHOSPHATE;2-CHLORO-1,3-DIMETHYL-2-IMIDAZOLINIUM HEXAFLUOROPHOSPHATE;CIP 25g;[M2ClIm]PF6;2-Chloro-1,3-dimethy;2-CHLORO-1,3-DIMETHYLIMIDAZOLINIUM PF6;2-Chlor-1,3-dimethyl-imidazolidinium-hexaf;2-chloro-1,3-dimethyl-4,5-dihydroimidazol-1-ium;CIP,2-Chloro-1,3-diMethyliMidazolidiniuMhexafluorop
CBNumber: CB2414339
Molecular Formula: C5H10ClN2.F6P
Formula Weight: 278.56
MOL File: 101385-69-7.mol

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2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate Property

Melting point:: 231-233 °C (lit.)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: acetonitrile: 0.1 g/mL, clear
form: powder to crystal
color: White to Almost white
Sensitive: Moisture & Light Sensitive
BRN: 5369058
InChI: InChI=1S/C5H10ClN2.F6P/c1-7-3-4-8(2)5(7)6;1-7(2,3,4,5)6/h3-4H2,1-2H3;/q+1;-1
InChIKey: CNAKHAGVVMOXFE-UHFFFAOYSA-N
SMILES: [P-](F)(F)(F)(F)(F)F.C1(Cl)=[N+](C)CCN1C
CAS DataBase Reference: 101385-69-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 8-10-21
HS Code: 29332900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 420336
Product name: 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate
Purity: 98%
Packaging: 5g
Price: $138
Updated: 2025/07/31

TCI Chemical

Product number: C1651
Product name: 2-Chloro-1,3-dimethylimidazolinium Hexafluorophosphate
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $35
Updated: 2025/07/31

TCI Chemical

Product number: C1651
Product name: 2-Chloro-1,3-dimethylimidazolinium Hexafluorophosphate
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $146
Updated: 2025/07/31

TRC

Product number: C596043
Product name: 2-Chloro-1,3-dimethyl-4,5-dihydro-1H-imidazol-3-iumHexafluorophosphate(V)
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Ark Pharm

Product number: P000676661
Product name: 2-Chloro-1,3-dimethyl-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate(V)
Purity: 97+%
Packaging: 1g
Price: $7
Updated: 2021/12/16

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2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

Reactant for synthesis of:
Diazo-transfer reagents

Reagent for synthesis of:
Cannabinoid CB1 receptor agonists
Selective small-molecule melanocortin-4 receptor agonists
Imidazoles as selective cannabinoid CB2 receptor antagonists
Cyclic alpha-peptoids
Cyclic melanotropin peptide analogues selective for the human melanocortin-4 receptor

General Description

2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate is a reagent used for the coupling and esterification of sterically hindered amino acids.^[1]

reaction suitability

reaction type: Coupling Reactions

Solubility in organics

2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate is soluble in DMF; partially soluble in H2O, MeOH, EtOAc, CH2Cl2, and CHCl3.

storage

2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate (CIP) can be stored refrigerated for at least 5 years without loss of reactivity. CIP is an irritant and should be used in a fumehood, when possible.

References

1. (a) Humphery, J. M.; Chamberlin, R., Chem. Rev. 1997, 97, 2243. (b) Albericio, F.; Carpino, L. A., Methods Enzymol. 1997, 289, 104

2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate 101385-69-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate 101385-69-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate 101385-69-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

101385-69-7, 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphateRelated Search:

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CIP

2-Chlor-1,3-dimethyl-imidazolidinium-hexafluorophosphat

2-CHLORO-1,3-DIMETHYLIMIDAZOLINIUM HEXAFLUOROPHOSPHATE 98+%

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CIP,2-Chloro-1,3-diMethyliMidazolidiniuMhexafluorop

CIP 25g

2-Chloro-1,3-dimethylimidazolinium hexafluorophosphate≥ 98%(HPLC)

2-Chlor-1,3-dimethyl-imidazolidinium-hexaf

2-Chloro-4,5-dihydro-1,3-dimethyl-1H-imidazolium hexafluorophosphate

2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate 98%

2-chloro-1,3-dimethyl-imidazolidin-1-ium hexafluorophosphate

2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate(CIP)

[M2ClIm]PF6

2-Chloro-1,3-dimethylimidazolinium Hexafluorophosphate &gt

1H-Imidazolium, 2-chloro-4,5-dihydro-1,3-dimethyl-, hexafluorophosphate(1-) (1:1)

2-Chloro-1,3-dimethyl-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate(V)(CIP)

2-chloro-1,3-dimethyl-4,5-dihydroimidazol-1-ium

2-Chloro-1,3-dimethylimidazolidium hexafluorophosphate

101385-69-7

C5H10F6N2PCl

C5H10ClF6N2P

C5H10ClF6N2P2

Coupling

Synthetic Reagents

Phosphonium/Uronium/Formamidinium

Peptide Synthesis

Condensation & Active Esterification

Coupling Reactions (Peptide Synthesis)

Biochemistry

Condensation & Active Esterification

Coupling Reactions (Peptide Synthesis)

Peptide Synthesis

Synthetic Organic Chemistry