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2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate

Product Name
2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate
CAS No.
101385-69-7
Chemical Name
2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate
Synonyms
CIP;2-CHLORO-1,3-DIMETHYLIMIDAZOLINIUM HEXAFLUOROPHOSPHATE;2-CHLORO-1,3-DIMETHYL-2-IMIDAZOLINIUM HEXAFLUOROPHOSPHATE;CIP 25g;[M2ClIm]PF6;2-Chloro-1,3-dimethy;2-CHLORO-1,3-DIMETHYLIMIDAZOLINIUM PF6;2-Chlor-1,3-dimethyl-imidazolidinium-hexaf;2-chloro-1,3-dimethyl-4,5-dihydroimidazol-1-ium;CIP,2-Chloro-1,3-diMethyliMidazolidiniuMhexafluorop
CBNumber
CB2414339
Molecular Formula
C5H10ClN2.F6P
Formula Weight
278.56
MOL File
101385-69-7.mol
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2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate Property

Melting point:
231-233 °C (lit.)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
acetonitrile: 0.1 g/mL, clear
form 
powder to crystal
color 
White to Almost white
Sensitive 
Moisture & Light Sensitive
BRN 
5369058
InChI
InChI=1S/C5H10ClN2.F6P/c1-7-3-4-8(2)5(7)6;1-7(2,3,4,5)6/h3-4H2,1-2H3;/q+1;-1
InChIKey
CNAKHAGVVMOXFE-UHFFFAOYSA-N
SMILES
[P-](F)(F)(F)(F)(F)F.C1(Cl)=[N+](C)CCN1C
CAS DataBase Reference
101385-69-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
8-10-21
HS Code 
29332900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
420336
Product name
2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate
Purity
98%
Packaging
5g
Price
$138
Updated
2025/07/31
TCI Chemical
Product number
C1651
Product name
2-Chloro-1,3-dimethylimidazolinium Hexafluorophosphate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$35
Updated
2025/07/31
TCI Chemical
Product number
C1651
Product name
2-Chloro-1,3-dimethylimidazolinium Hexafluorophosphate
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$146
Updated
2025/07/31
TRC
Product number
C596043
Product name
2-Chloro-1,3-dimethyl-4,5-dihydro-1H-imidazol-3-iumHexafluorophosphate(V)
Packaging
50mg
Price
$45
Updated
2021/12/16
Ark Pharm
Product number
P000676661
Product name
2-Chloro-1,3-dimethyl-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate(V)
Purity
97+%
Packaging
1g
Price
$7
Updated
2021/12/16
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2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

Reactant for synthesis of:
Diazo-transfer reagents

Reagent for synthesis of:
Cannabinoid CB1 receptor agonists
Selective small-molecule melanocortin-4 receptor agonists
Imidazoles as selective cannabinoid CB2 receptor antagonists
Cyclic alpha-peptoids
Cyclic melanotropin peptide analogues selective for the human melanocortin-4 receptor

General Description

2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate is a reagent used for the coupling and esterification of sterically hindered amino acids.[1]

reaction suitability

reaction type: Coupling Reactions

Solubility in organics

2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate is soluble in DMF; partially soluble in H2O, MeOH, EtOAc, CH2Cl2, and CHCl3.

storage

2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate (CIP) can be stored refrigerated for at least 5 years without loss of reactivity. CIP is an irritant and should be used in a fumehood, when possible.

References

1. (a) Humphery, J. M.; Chamberlin, R., Chem. Rev. 1997, 97, 2243. (b) Albericio, F.; Carpino, L. A., Methods Enzymol. 1997, 289, 104

2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate Suppliers

Americas 1 China 170 Europe 1 France 1 Germany 5 India 5 Japan 5 Poland 1 Switzerland 2 United Kingdom 10 United States 42 Global 243
Interchim SA
Tel
--
Fax
--
Email
him@interchim.com
Country
France
ProdList
2725
Advantage
58
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View Lastest Price from 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate 101385-69-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate 101385-69-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate 101385-69-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

101385-69-7, 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphateRelated Search:

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  • 2-CHLORO-1,3-DIMETHYL-2-IMIDAZOLINIUM HEXAFLUOROPHOSPHATE
  • 2-CHLORO-1,3-DIMETHYLIMIDAZOLIDINIUM HEXAFLUOROPHOSPHATE
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  • 2-CHLORO-1,3-DIMETHYLIMIDAZOLINIUM PF6
  • CIP
  • 2-Chlor-1,3-dimethyl-imidazolidinium-hexafluorophosphat
  • 2-CHLORO-1,3-DIMETHYLIMIDAZOLINIUM HEXAFLUOROPHOSPHATE 98+%
  • 2-Chloro-1,3-dimethy
  • CIP 2-Chloro-1,3-diMethyliMidazolidiniuM hexafluorophosphate
  • 2-Chloro-1,3-diMethyl-4,5-dihydro-1H-iMidazol-3-iuM hexafluorophosphate(V)
  • CIP,2-Chloro-1,3-diMethyliMidazolidiniuMhexafluorop
  • CIP 25g
  • 2-Chloro-1,3-dimethylimidazolinium hexafluorophosphate≥ 98%(HPLC)
  • 2-Chlor-1,3-dimethyl-imidazolidinium-hexaf
  • 2-Chloro-4,5-dihydro-1,3-dimethyl-1H-imidazolium hexafluorophosphate
  • 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate 98%
  • 2-chloro-1,3-dimethyl-imidazolidin-1-ium hexafluorophosphate
  • 2-Chloro-1,3-dimethylimidazolidinium hexafluorophosphate(CIP)
  • [M2ClIm]PF6
  • 2-Chloro-1,3-dimethylimidazolinium Hexafluorophosphate &gt
  • 1H-Imidazolium, 2-chloro-4,5-dihydro-1,3-dimethyl-, hexafluorophosphate(1-) (1:1)
  • 2-Chloro-1,3-dimethyl-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate(V)(CIP)
  • 2-chloro-1,3-dimethyl-4,5-dihydroimidazol-1-ium
  • 2-Chloro-1,3-dimethylimidazolidium hexafluorophosphate
  • 101385-69-7
  • C5H10F6N2PCl
  • C5H10ClF6N2P
  • C5H10ClF6N2P2
  • Coupling
  • Synthetic Reagents
  • Phosphonium/Uronium/Formamidinium
  • Peptide Synthesis
  • Condensation & Active Esterification
  • Coupling Reactions (Peptide Synthesis)
  • Biochemistry
  • Condensation & Active Esterification
  • Coupling Reactions (Peptide Synthesis)
  • Peptide Synthesis
  • Synthetic Organic Chemistry