3-CHLOROBENZHYDRAZIDE

Product Name: 3-CHLOROBENZHYDRAZIDE
CAS No.: 1673-47-8
Chemical Name: 3-CHLOROBENZHYDRAZIDE
Synonyms: RMA-106;ASISCHEM D51116;AKOS BBS-00004508;SPECS AN-068/40169986;3-CHLOROBENZHYDRAZIDE;3-chlorobenzohydrazide;3-Chlorobenzoylhydrazine;3-CHLOROBENZOIC HYDRAZIDE;3-Chlorobenzohydrazide >3-Chlorobenzhydrazide, 98+%
CBNumber: CB2424392
Molecular Formula: C7H7ClN2O
Formula Weight: 170.6
MOL File: 1673-47-8.mol

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3-CHLOROBENZHYDRAZIDE Property

Melting point:: 155-156°C
Density: 1.323±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: powder to crystal
pka: 11.86±0.10(Predicted)
color: White to Light yellow
BRN: 973243
InChI: InChI=1S/C7H7ClN2O/c8-6-3-1-2-5(4-6)7(11)10-9/h1-4H,9H2,(H,10,11)
InChIKey: PHRDZSRVSVNQRN-UHFFFAOYSA-N
SMILES: C(NN)(=O)C1=CC=CC(Cl)=C1
CAS DataBase Reference: 1673-47-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HazardClass: IRRITANT
HS Code: 29280090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C2648
Product name: 3-Chlorobenzohydrazide
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $33
Updated: 2025/07/31

TCI Chemical

Product number: C2648
Product name: 3-Chlorobenzohydrazide
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $112
Updated: 2025/07/31

Usbiological

Product number: 270581
Product name: 3-Chlorobenzohydrazide
Packaging: 5g
Price: $317
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC61152
Product name: 3-Chlorobenzhydrazide
Packaging: 50g
Price: $291
Updated: 2021/12/16

ChemScene

Product number: CS-W010776
Product name: 3-Chlorobenzohydrazide
Purity: >97.0%
Packaging: 100g
Price: $184
Updated: 2021/12/16

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3-CHLOROBENZHYDRAZIDE Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Antimicrobial activity

3-Chlorobenzhydrazide is a dihedral molecule that can be classified as an antibacterial and antimycobacterial agent. The crystal x-ray diffraction study revealed that 3-chlorobenzhydrazide forms a hydrogen bond with hydroxyl groups of amino acids in proteins. This property makes it an effective antibacterial agent against Gram-positive bacteria such as staphylococci and Mycobacteria tuberculosis.

Synthesis

535-80-8

1673-47-8

General procedure for the synthesis of 3-chlorobenzhydrazide from 3-chlorobenzoic acid: a mixture of 3-chlorobenzoic acid (0.5 g, 3.19 mmol), 1,3-dicyclohexylcarbodiimide (0.72 g, 3.51 mmol), and 4-dimethylaminopyridine (0.04 g, 0.32 mmol) in ethanol was stirred for 1.5 h at room temperature. The white solid was collected by filtration and the filtrate was diluted with dichloromethane (100 mL). The organic phase was washed sequentially with 1N sodium bisulfate solution (100 mL), saturated sodium bicarbonate solution (100 mL), water (100 mL) and brine (100 mL). The organic layer was dried with anhydrous magnesium sulfate, filtered and the filtrate was concentrated under reduced pressure. The resulting crude product was dissolved in ethanol (15 mL) and hydrazine monohydrate (0.46 mL, 9.58 mmol) was added. The reaction mixture was stirred at room temperature overnight. Subsequently, the reaction mixture was concentrated to dryness under reduced pressure. The residue was purified by silica gel column chromatography with the eluent being a dichloromethane solution of 3% methanol to give 0.29 g (53% yield) of 3-chlorobenzohydrazide as a white solid.

References

[1] European Journal of Medicinal Chemistry, 2017, vol. 138, p. 396 - 406
[2] Patent: US2003/55085, 2003, A1
[3] Journal of Chemical Research, 2010, vol. 34, # 12, p. 680 - 683
[4] Journal of Chemical Research, 2011, vol. 35, # 4, p. 234 - 237
[5] Monatshefte fur Chemie, 2010, vol. 141, # 4, p. 479 - 484

3-CHLOROBENZHYDRAZIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-CHLOROBENZHYDRAZIDE Suppliers

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View Lastest Price from 3-CHLOROBENZHYDRAZIDE manufacturers

Career Henan Chemical Co

Product: 3-CHLOROBENZHYDRAZIDE 1673-47-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-07-03

1673-47-8, 3-CHLOROBENZHYDRAZIDERelated Search:

2-Chlorobenzhydrazide,98%,o-Chlorobenzhydrazide,2-CHLOROBENZHYDRAZIDE 4-CHLOROBENZHYDRAZIDE,p-Chlorobenzhydrazide,4-Chlorobenzhydrazide, 98+% 5-BROMO-2-CHLOROBENZHYDRAZIDE 98%,5-BROMO-2-CHLOROBENZHYDRAZIDE Carbohydrazide 2,5-DICHLOROBENZHYDRAZIDE 3-CHLOROBENZHYDRAZIDE (2-AMINO-5-CHLOROBENZOYL)HYDRAZIDE 3,5-DICHLOROBENZHYDRAZIDE 3,4-DICHLOROBENZENE-1-CARBOHYDRAZIDE 4-BROMO-3-CHLOROBENZHYDRAZIDE 4-BROMO-2-CHLOROBENZHYDRAZIDE 2-BROMO-4-CHLOROBENZHYDRAZIDE 2-BROMO-5-CHLOROBENZHYDRAZIDE 3-BROMO-4-CHLOROBENZHYDRAZIDE 3-CHLORO-N'-([5-OXO-3-(TRIFLUOROMETHYL)-1,5-DIHYDRO-4H-PYRAZOL-4-YLIDEN]METHYL)BENZENECARBOHYDRAZIDE N'-Phenyl-p-chlorobenzhydrazide 3,5-DICHLORO-4-METHOXYBENZENECARBOHYDRAZIDE 1-(2-AMINO-5-CHLOROBENZOYL)-1-METHYLHYDRAZINE

SPECS AN-068/40169986

ASISCHEM D51116

3-CHLOROBENZOIC HYDRAZIDE

3-CHLOROBENZOIC ACID HYDRAZIDE

3-CHLOROBENZHYDRAZIDE

3-CHLOROBENZENE-1-CARBOHYDRAZIDE

AKOS BBS-00004508

3-chlorobenzohydrazide

3-Chlorobenzenecarbohydrazide

3-CHLOROBENZOIC HYDRAZIDE, 98+%

Benzoic acid, 3-chloro-, hydrazide

3-Chlorobenzhydrazide, 98+%

30-ethyl-33-(1-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,

3-Chlorobenzohydrazide &gt

3-Chlorobenzoylhydrazine

RMA-106

1673-47-8

Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes

Chlorine Compounds