D-arabinitol
- Product Name
- D-arabinitol
- CAS No.
- 488-82-4
- Chemical Name
- D-arabinitol
- Synonyms
- D-ARA-OL;D-Lyxitol;ARABINITOL;D(+)-ARABIT;D-ARABINITOL;arabinitol,D-;Arabinitol, D-;dextro-arabitol;D-(+)-ARABINITOL;ARABITOL, D-(+)-
- CBNumber
- CB2424877
- Molecular Formula
- C5H12O5
- Formula Weight
- 152.15
- MOL File
- 488-82-4.mol
D-arabinitol Property
- Melting point:
- 101-104 °C
- Boiling point:
- 194.6°C (rough estimate)
- alpha
- +10～+14゜(20℃/D)(c=5,Na2B4O7 soln.)
- Density
- 1.1497 (rough estimate)
- refractive index
- 1.3960 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- H2O: 0.1 g/mL, clear, colorless
- form
- Fine Crystalline Powder
- pka
- 13.24±0.20(Predicted)
- color
- White to off-white
- optical activity
- +7.82
- Water Solubility
- Soluble in water (50 mg/ml).
- Merck
- 14,762
- BRN
- 1720520
- LogP
- -3.774 (est)
- CAS DataBase Reference
- 488-82-4(CAS DataBase Reference)
- EPA Substance Registry System
- D-Arabinitol (488-82-4)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- F
- 3-10
- TSCA
- Yes
- HS Code
- 29054980
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- A3381
- Product name
- D-(+)-Arabitol
- Purity
- ≥99%
- Packaging
- 25g
- Price
- $333
- Updated
- 2024/03/01
- Product number
- A3381
- Product name
- D-(+)-Arabitol
- Purity
- ≥99%
- Packaging
- 100g
- Price
- $1110
- Updated
- 2024/03/01
- Product number
- A0516
- Product name
- D-(+)-Arabitol
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $28
- Updated
- 2024/03/01
- Product number
- A0516
- Product name
- D-(+)-Arabitol
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $225
- Updated
- 2024/03/01
- Product number
- A17801
- Product name
- D-(+)-Arabitol, 99%
- Packaging
- 5g
- Price
- $52.4
- Updated
- 2024/03/01
D-arabinitol Chemical Properties,Usage,Production
Description
D-arabinitol is a characteristic metabolic product of candida species. While candida ssp. produces exclusively D-arabinitol, L-arabinitol is developed by the body’s own metabolism. D-arabinitol serum levels increase if candida yeasts proliferate within the organism and cause invasive Candidiasis. Both D-arabinitol and L-arabinitol are present in normal urine, and can easily be measured by gas chromatography of urine samples collected on filter paper.
Chemical Properties
white to off-white fine crystalline powder
Occurrence
D-Arabinitol (lyxitol) is found in lichens; in a variety of fungi; in the urediospores of wheat stem rust; in the dried herbiage of the Peruvian shrub, pichi, along with D-mannitol, dulcitol, and perseitol; and in the avocado. It is formed by fermentation of glucose and in 40% yields using blackstrap molasses. D-Arabinitol is formed by catalytic hydrogenation of D-arabinose in the presence of Raney nickel and from the γ-lactones of D-arabinonic and D-lyxonic acids by reduction with sodium borohydride.
Uses
D-Arabitol, a rare sugar alcohol, is a substrate used to identify, differentiate and characterize enzyme such as the gluconobacter oxydans dehydrogenase(s), Gox2181, hyperthermophilic D-arabitol dehydrogenase from Thermotoga maritime and NAD-dependent D-arabitoldehydrogenase from acetic acid bacterium, Acetobacter suboxydans.
Definition
ChEBI: D-arabinitol is the D-enantiomer of arabinitol. It is an enantiomer of a L-arabinitol. It is a metabolite found in the aging mouse brain.
Biotechnological Applications
D-arabinitol detection
Another approach to the diagnosis of invasive candidosis involves the detection in serum or urine of a metabolite, D-arabinitol, which is produced by most of the medically important Candida species with the exception of C. krusei and perhaps C. glabrata. Various methods have been developed to measure D-arabinitol concentrations in human serum and urine, including enzymatic-fluorometric and enzymatic-colorimetric procedures. Because increased levels of arabinitol are also found in human body fluids when renal function is impaired, the results are reported as the D-arabinitol- creatinine ratio. Although several large studies have demonstrated that patients with candidaemia have ele- vated serum D-arabinitol- creatinine ratios, this approach has still to achieve widespread clinical use.
Purification Methods
This pentol, which occurs in lichens and fungi, is purified by recrystallisation from 90% EtOH or MeOH. [Ashina & Yamagita Chem Ber 67 801 1934, derivarives: Nakagawa et al. Bull Chem Soc Jpn 40 2150 1967, Prince & Reichstein Helv Chim Acta 20 101 1937, Hough & Theobald Methods in Carbohydrate Chemistry I 94 1962, Academic Press, Beilstein 1 IV 2832.]
D-arabinitol Preparation Products And Raw materials
Raw materials
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View Lastest Price from D-arabinitol manufacturers
- Product
- D-arabinitol 488-82-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-07
- Product
- D-Arabitol 488-82-4
- Price
- US $2300.00/Kg
- Min. Order
- 1Kg
- Purity
- 97
- Supply Ability
- 500 Kg
- Release date
- 2024-06-23
- Product
- D-ARABINITOL 488-82-4
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10MT
- Release date
- 2018-12-21