ChemicalBook > CAS DataBase List > METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE

METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE

Product Name: METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE
CAS No.: 208465-72-9
Chemical Name: METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE
Synonyms: METHYL 2-CHLOROMETHYL-4-OXAZOLECARBOXYLATE;METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE;METHYL 2-(CHLROMETHYL)-1,3-OXAZOLE-4-CARBOXYLATE;2-(Chloromethyl)-4-(methoxycarbonyl)-1,3-oxazole;METHYL 2-(CHLOROMETHYL)-1,3-OXAZOLE-4-CARBOXYLATE;Methyl2-(chloromethyl)-1,3-oxazole-4-carboxylate97%;2-CHLOROMETHYL-OXAZOLE-4-CARBOXYLIC ACID METHYL ESTER;Methyl 2-(chloromethyl)-1,3-oxazole-4-carboxylate 97%;Methyl (2-Chloromethyl)Oxazole-4-Carboxylate(WX630102);4-Oxazolecarboxylic acid, 2-(chloroMethyl)-, Methyl ester
CBNumber: CB2425465
Molecular Formula: C6H6ClNO3
Formula Weight: 175.57
MOL File: 208465-72-9.mol

Less

METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE Property

Melting point:: 74 °C
Boiling point:: 230℃
Density: 1.339
Flash point:: 93℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: -2.41±0.10(Predicted)
color: Off-white

Less

Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 22-26-36/37/39-45
Hazard Note: Corrosive
HS Code: 2934999090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H314Causes severe skin burns and eye damage
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

TRC

Product number: M218855
Product name: Methyl2-(Chloromethyl)oxazole-4-carboxylate
Packaging: 500mg
Price: $175
Updated: 2021/12/16

AK Scientific

Product number: Y8207
Product name: Methyl2-(chloromethyl)oxazole-4-carboxylate
Packaging: 1g
Price: $177
Updated: 2021/12/16

Matrix Scientific

Product number: 069431
Product name: Methyl (2-chloromethyl)oxazole-4-carboxylate
Purity: 97%
Packaging: 1g
Price: $202
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H23-5-Z3
Product name: Methyl 2-(chloromethyl)-1,3-oxazole-4-carboxylate
Purity: 97%
Packaging: 1g
Price: $247
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: M11416
Product name: Methyl(2-chloromethyl)oxazole-4-carboxylate
Purity: 95%
Packaging: 1g
Price: $90
Updated: 2021/12/16

Less

METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

3018-12-0

5680-80-8

208465-72-9

GENERAL STEPS: Sodium methanolate (25.00 mg, 0.46 mmol) was dissolved in anhydrous methanol (4.50 mL) and dry dichloromethane (30.00 mL) under nitrogen protection and cooled to 0 °C. Dichloroacetonitrile (5.00 g, 45.50 mmol) was slowly added to this stirred solution and stirring was continued for 1 hour at 0°C. Subsequently, L-serine methyl ester hydrochloride (7.00 g, 45.50 mmol) was added and the reaction mixture was warmed to 25 °C and stirred for 12 hours. Upon completion of the reaction, water was added and the aqueous phase was extracted with dichloromethane (3 x 25.00 mL). The organic layers were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was dissolved in dichloromethane (50.00 mL) and N,N-diisopropylethylamine (11.90 mL, 68.30 mmol) was added. The reaction mixture was stirred at 50 °C for 5 hours, followed by continued stirring at 25 °C for 12 hours. At the end of the reaction, water was added and the aqueous phase was extracted with dichloromethane (3 x 25.00 mL). The organic layers were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The product did not require further purification (quantitative yield).ESI-MS m/z: 176 [M + H]+, 198 [M + Na]+; 1H NMR (300 MHz, CDCl3) δ 3.92 (s, 3H), 4.63 (s, 2H), 8.25 (s, 1H).

References

[1] Tetrahedron Letters, 2016, vol. 57, # 8, p. 920 - 923

METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE Suppliers

Belgium 1 China 58 Germany 2 Hungary 1 India 2 United Kingdom 5 United States 14 Global 83

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai Balmxy Pharmaceutical Co., Ltd

Tel: 021-24206007 13764915196
Fax: 86-021-23027023
Email: sales@balmxy.com
Country: China
ProdList: 6874
Advantage: 55

Bellen Chemistry Co., Ltd.

Tel: 010-60400365-8001 15910885229
Fax: 010-60400361
Email: service@bellenchem.com
Country: China
ProdList: 4514
Advantage: 60

3A SpeedChemical Inc

Tel: 21-65679720
Fax: 0086-21-5186 1128
Email: service@speedchemical.com
Country: China
ProdList: 604
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-58088081 Q2635253576
Fax: QQ3382968513
Email: hailey@shsendpharm.com
Country: China
ProdList: 2081
Advantage: 55

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Wuxi KaideRui Pharmaceutical Technology Co., Ltd

Tel: 19906241957
Fax: -
Email: 1557216087@qq.com
Country: China
ProdList: 1837
Advantage: 55

Sichuan BaiPeng Biotechnology Co., Ltd.

Tel: 028-65791793 18140026355
Fax: QQ568470422
Email: 568470422@qq.com
Country: China
ProdList: 9997
Advantage: 58

Wuxi AppTec

Tel: 022-59987777 13552403979
Email: jia_guoqiang@wuxiapptec.com
Country: China
ProdList: 22345
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000 13917643586;
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9856
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

Hahui (Shanghai) Pharmaceutical Technology Co., Ltd.

Tel: 021-13472633-721 13472633721
Email: 454407203@qq.com
Country: China
ProdList: 552
Advantage: 58

Shanghai Songfan Pharmaceutical Technology Co., Ltd.

Tel: 17321241880
Email: 485229790@qq.com
Country: China
ProdList: 1750
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

Wuhan Chemwish Technology Co., Ltd

Tel: 027-67849912
Email: sales@chemwish.com
Country: CHINA
ProdList: 10821
Advantage: 58

Shaanxi borno biotechnology co., LTD

Tel: +86-13759708231
Email: asherw9@hotmail.com
Country: China
ProdList: 2373
Advantage: 58

Shanghai Jiegu Biotechnology Co., Ltd.

Tel: 021-51698675
Email: sales@jiejiegroup.com
Country: China
ProdList: 8020
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Shanghai Hanlin biology science and technology co., ltd

Tel: 183-0212-4410 18302124410
Email: Djt18302124410@163.com
Country: China
ProdList: 3000
Advantage: 58

Hubei Co-prosperity Medicine Technonlogy Co., Ltd

Tel: 2383948258 19172820304
Email: 2383948258@qq.com
Country: China
ProdList: 12987
Advantage: 58

SINO High Goal Chemical Technology Co., Ltd.

Tel: 021-57646680 18306277365
Email: guoxin@chembiobanksh.com
Country: China
ProdList: 2666
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Qi Qi hang Biotechnology Co., Ltd.

Tel: 15870833005
Email: 2232044025@qq.com
Country: China
ProdList: 8206
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Hubei Hannuo Pharmaceutical Technology Co., Ltd

Tel: 18662190603
Email: 437347250@qq.com
Country: China
ProdList: 7325
Advantage: 58

Suzhou Meishi Biotechnology Co., Ltd.

Tel: 1173954148q
Email: meishipharma@126.com
Country: China
ProdList: 20033
Advantage: 58

Xuchang Fengfei New Materials Technology Co., Ltd

Tel: 19713077352
Email: 1038096457@qq.com
Country: China
ProdList: 2640
Advantage: 58

Shanghai Jianchao Biotechnology Co., LTD

Tel: 15021035486 18081542813
Email: 1804873256@qq.com
Country: China
ProdList: 6684
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
Advantage: 58

Less

View Lastest Price from METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE manufacturers

Career Henan Chemical Co

Product: METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE 208465-72-9
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200KG
Release date: 2018-12-23

208465-72-9, METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATERelated Search:

2-Chloromethyloxazole ETHYL-4-METHYL-3,5-OXAZOLECARBOXYLATE METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE

METHYL 2-(CHLOROMETHYL)-1,3-OXAZOLE-4-CARBOXYLATE

METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE

METHYL 2-CHLOROMETHYL-4-OXAZOLECARBOXYLATE

2-CHLOROMETHYL-OXAZOLE-4-CARBOXYLIC ACID METHYL ESTER

4-Oxazolecarboxylic acid, 2-(chloroMethyl)-, Methyl ester

2-(Chloromethyl)-4-(methoxycarbonyl)-1,3-oxazole

Methyl 2-(chloromethyl)-1,3-oxazole-4-carboxylate 97%

Methyl2-(chloromethyl)-1,3-oxazole-4-carboxylate97%

Methyl (2-Chloromethyl)Oxazole-4-Carboxylate(WX630102)

METHYL 2-(CHLROMETHYL)-1,3-OXAZOLE-4-CARBOXYLATE

208465-72-9

pharmacetical

Building Blocks

Oxazole