2-Chloromethyloxazole

Product Name: 2-Chloromethyloxazole
CAS No.: 185246-17-7
Chemical Name: 2-Chloromethyloxazole
Synonyms: 2-CHLOROMETHYL-OXAZOLE;Lactic Acid Impurity 17;OXAZOLE, 2-(CHLOROMETHYL)-;2-(Chloromethyl)-1,3-oxazole
CBNumber: CB8171649
Molecular Formula: C4H4ClNO
Formula Weight: 117.53
MOL File: 185246-17-7.mol

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2-Chloromethyloxazole Property

Boiling point:: 143.5±23.0 °C(Predicted)
Density: 1.261±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
form: liquid
pka: 0.37±0.10(Predicted)
color: Yellow to brown

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: C384258
Product name: 2-Chloromethyl-oxazole
Packaging: 10mg
Price: $45
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-5-29
Product name: 2-Chloromethyloxazole
Packaging: 250mg
Price: $148
Updated: 2021/12/16

Matrix Scientific

Product number: 089886
Product name: 2-(Chloromethyl)oxazole
Purity: 93+%
Packaging: 250mg
Price: $163
Updated: 2021/12/16

AK Scientific

Product number: X7958
Product name: 2-Chloromethyloxazole
Packaging: 250mg
Price: $184
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-5-29
Product name: 2-Chloromethyloxazole
Packaging: 1g
Price: $365
Updated: 2021/12/16

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2-Chloromethyloxazole Chemical Properties,Usage,Production

Synthesis

130551-92-7

185246-17-7

General procedure for the synthesis of 2-(chloromethyl)oxazole from 2-hydroxymethyl oxazole: Thionyl chloride (SOCl2, 3.25 mL, 45 mmol) was added slowly and dropwise to a solution of 2-hydroxymethyl oxazole (450 mg, 4.5 mmol) in dichloromethane (DCM, 25 mL) at 0 °C. The reaction mixture was stirred at 0 °C for 1 hour. Subsequently, water (50 mL) and ethyl acetate (EtOAc, 60 mL) were added to the reaction system for extraction. The organic and aqueous phases were separated, and the organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford 2-(chloromethyl)oxazole as a white solid (200 mg, 1.7 mmol, 37% yield).

References

[1] Patent: WO2017/93543, 2017, A2. Location in patent: Page/Page column 101
[2] Patent: WO2007/34144, 2007, A1. Location in patent: Page/Page column 93
[3] Patent: WO2011/35009, 2011, A1. Location in patent: Page/Page column 46

2-Chloromethyloxazole Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloromethyloxazole Suppliers

China 86 India 2 Switzerland 1 United Kingdom 4 United States 15 Global 108

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185246-17-7, 2-ChloromethyloxazoleRelated Search:

Chloromethane tert-Butyldimethylsilyl chloride Sulfamethoxazole DIMETHYLTHEXYLSILYL CHLORIDE 4-(Chloromethyl)benzoic acid 5-TERT-BUTYL-2-(CHLOROMETHYL)OXAZOLE METHYL (2-CHLOROMETHYL)OXAZOLE-4-CARBOXYLATE 2-(CHLOROMETHYL)-5-PHENYL-1,3-OXAZOLE 5-CHLORO-2-(CHLOROMETHYL)-1,3-BENZOXAZOLE 2-DICHLOROMETHYL-OXAZOLE 2-(CHLOROMETHYL)-6-NITRO-1,3-BENZOXAZOLE METHYL 2-[2-(CHLOROMETHYL)-1,3-BENZOXAZOL-5-YL]ACETATE 2-(CHLOROMETHYL)-5-(4-CHLOROPHENYL)1,3-OXAZOLE, 97+% 2-(CHLOROMETHYL)-6-METHYL-1,3-BENZOXAZOLE 2-(CHLOROMETHYL)-5-METHYL-1,3-BENZOXAZOLE 2-(CHLOROMETHYL)[1,3]OXAZOLO[4,5-B]PYRIDINE 5-(TERT-BUTYL)-2-(CHLOROMETHYL)-1,3-BENZOXAZOLE 2-TRICHLOROMETHYL-BENZOOXAZOLE

2-(Chloromethyl)-1,3-oxazole

OXAZOLE, 2-(CHLOROMETHYL)-

2-CHLOROMETHYL-OXAZOLE

Lactic Acid Impurity 17

185246-17-7