2-(1H-PYRAZOL-3-YL)PYRIDINE
Uses- Product Name
- 2-(1H-PYRAZOL-3-YL)PYRIDINE
- CAS No.
- 75415-03-1
- Chemical Name
- 2-(1H-PYRAZOL-3-YL)PYRIDINE
- Synonyms
- 2-(1H-pyrazol-5-yl)pyridine;DK7402;BUTTPARK 17\04-92;2-(2H-pyrazol-3-y;3-(2-Pyridyl)pyrazol;3-(2-Pyridyl)pyrazole;2-(3-Pyrazolyl)pyridine;3-(Pyridin-2-yl)pyrazole;2-(PYRAZOL-3-YL)-PYRIDINE;3-(Pyridin-2-yl)-1H-pyrazol
- CBNumber
- CB2430115
- Molecular Formula
- C8H7N3
- Formula Weight
- 145.16
- MOL File
- 75415-03-1.mol
2-(1H-PYRAZOL-3-YL)PYRIDINE Property
- Melting point:
- 119-120°C
- Boiling point:
- 362.2±17.0 °C(Predicted)
- Density
- 1.214±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 11.36±0.10(Predicted)
- color
- White to Light yellow
- λmax
- 303nm(CH3CN aq.)(lit.)
- InChI
- InChI=1S/C8H7N3/c1-2-5-9-7(3-1)8-4-6-10-11-8/h1-6H,(H,10,11)
- InChIKey
- HKEWOTUTAYJWQJ-UHFFFAOYSA-N
- SMILES
- C1(C2C=CNN=2)=NC=CC=C1
- CAS DataBase Reference
- 75415-03-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- P2211
- Product name
- 2-(1H-Pyrazol-3-yl)pyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $81
- Updated
- 2025/07/31
- Product number
- P2211
- Product name
- 2-(1H-Pyrazol-3-yl)pyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $276
- Updated
- 2025/07/31
- Product number
- B529803
- Product name
- 2-(1H-Pyrazol-3-yl)pyridine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 3H32-1-H2
- Product name
- 2-(1H-Pyrazol-3-yl)pyridine
- Packaging
- 250mg
- Price
- $24
- Updated
- 2021/12/16
- Product number
- 024679
- Product name
- 2-(1H-Pyrazol-3-yl)-pyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $29
- Updated
- 2021/12/16
2-(1H-PYRAZOL-3-YL)PYRIDINE Chemical Properties,Usage,Production
Uses
2-(1H-pyrazol-3-yl)pyridine is an organic intermediate that can be used to prepare a pyrazolidine alcohol-copper complex. This complex is a mononuclear Cu complex and exhibits antitumor activity.
Synthesis
75415-00-8
75415-03-1
Example 15 Synthesis of 2-(1H-pyrazol-3-yl)pyridine (17a): compound 16a (1 g, 6.2 mmol) was dissolved with hydrazine hydrate (2 mL) in ethanol (3.3 mL) and reacted at 60°C for 0.5 hrs. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was subsequently removed under vacuum to afford the pale yellow solid product 17a (874.7 mg) in 97.3% yield.1H-NMR (400 MHz, CDCl3): δ 8.66 (d, J = 4.8 Hz, 1H), 7.75 (d, J = 3.6 Hz, 2H), 7.67 (d, J = 2Hz, 1H), 7.23-7.27 (m, 1H), 6.81 (d, J = 2Hz, 1H).
References
[1] Patent: US2014/142144, 2014, A1. Location in patent: Paragraph 0235; 0236; 0237
[2] Patent: EP2738169, 2014, A1. Location in patent: Paragraph 0105; 0106; 0107
[3] Journal of the Chemical Society, Chemical Communications, 1994, # 24, p. 2751 - 2752
[4] European Journal of Inorganic Chemistry, 2007, # 26, p. 4197 - 4206
2-(1H-PYRAZOL-3-YL)PYRIDINE Preparation Products And Raw materials
Raw materials
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