ChemicalBook > CAS DataBase List > 2-Amino-6-methyl-5-nitropyridine

2-Amino-6-methyl-5-nitropyridine

Product Name
2-Amino-6-methyl-5-nitropyridine
CAS No.
22280-62-2
Chemical Name
2-Amino-6-methyl-5-nitropyridine
Synonyms
6-Amino-3-Nitro-2-Picolin;6-AMINO-3-NITRO-2-PICOLINE;2-AMINO-5-NITRO-6-PICOLINE;2-Amino-5-nitro-6-methylpyridi;6-Amino-3-nitro-2-picoline,98%;6-Amino-3-nitro-2-picoline ,97%;6-Methyl-5-nitro-2-pyridinaMine;6-methyl-5-nitro-pyridin-2-amine;2-AMINO-6-METHYL-5-NITROPYRIDINE;6-AMINO-3-NITRO-2-METHYLPYRIDINE
CBNumber
CB2430160
Molecular Formula
C6H7N3O2
Formula Weight
153.14
MOL File
22280-62-2.mol
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2-Amino-6-methyl-5-nitropyridine Property

Melting point:
185-189 °C
Boiling point:
276.04°C (rough estimate)
Density 
1.3682 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
2.97±0.37(Predicted)
form 
Powder
color 
Yellow
InChIKey
BGMZTBKXOFFTBJ-UHFFFAOYSA-N
CAS DataBase Reference
22280-62-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-20/21/22
Safety Statements 
36/37/39-26-22-36
HazardClass 
6.1
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2326
Product name
6-Amino-2-methyl-3-nitropyridine
Purity
>98.0%(GC)
Packaging
1g
Price
$63
Updated
2025/07/31
TCI Chemical
Product number
A2326
Product name
6-Amino-2-methyl-3-nitropyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$212
Updated
2025/07/31
TRC
Product number
A898138
Product name
2-Amino-6-methyl-5-nitropyridine
Packaging
1g
Price
$45
Updated
2021/12/16
TRC
Product number
A898138
Product name
2-Amino-6-methyl-5-nitropyridine
Packaging
10g
Price
$140
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA55142
Product name
2-Amino-6-methyl-5-nitropyridine
Packaging
10g
Price
$171.1
Updated
2021/12/16
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2-Amino-6-methyl-5-nitropyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Synthesis

1824-81-3

22280-62-2

General procedure for the synthesis of 2-amino-5-nitro-6-methylpyridine from 2-amino-6-methylpyridine: 10 mL of concentrated sulfuric acid was cooled to 0-1 °C and 2-amino-6-methylpyridine (20 g) was slowly added, keeping the temperature at 0 °C. Subsequently, 110 mL of nitric acid in the ratio of 1:1 by volume was slowly added, stirred at -1 °C and continued stirring at room temperature for 30 min. The reaction mixture was warmed up to 50 °C for 11 hours. After completion of the reaction, the reaction solution was extracted with ethyl acetate (EA). The ethyl acetate layer was washed with ammonia and then the ammonia layer was concentrated. Eventually, the solid product 2-amino-5-nitro-6-methylpyridine (18 g) was precipitated in 75% yield.

References

[1] Patent: CN105906621, 2016, A. Location in patent: Paragraph 0019
[2] Patent: WO2005/42464, 2005, A1. Location in patent: Page/Page column 32-33
[3] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 8, p. 1858 - 1868
[4] Patent: WO2009/30725, 2009, A2. Location in patent: Page/Page column 58
[5] Patent: EP1857444, 2007, A1. Location in patent: Page/Page column 20

2-Amino-6-methyl-5-nitropyridine Preparation Products And Raw materials

Raw materials

FUMING SULFURIC ACID 2-Amino-6-methylpyridine Ethyl acetate Nitric acid Dichloromethane Sodium hydroxide PETROLEUM ETHER

Preparation Products

5-METHOXY-1H-PYRROLO[3,2-B]PYRIDINE-2-CARBOXYLIC ACID (5-METHOXY-1H-PYRROLO[3,2-B]PYRIDIN-3-YL)-N,N-DIMETHYLMETHANAMINE 5-(BENZYLOXY)-1H-PYRROLO[3,2-B]PYRIDINE-2-CARBALDEHYDE 3-Amino-6-chloro-2-picoline 3-Amino-6-fluoro-2-methylpyridine 2-FLUORO-5-NITRO-6-PICOLINE 5-METHOXY-1H-PYRROLO[3,2-B]PYRIDINE-3-CARBALDEHYDE
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2-Amino-6-methyl-5-nitropyridine Suppliers

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View Lastest Price from 2-Amino-6-methyl-5-nitropyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-Amino-6-methyl-5-nitropyridine 22280-62-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-29
WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Amino-6-methyl-5-nitropyridine 22280-62-2
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min HPLC
Supply Ability
500KGS
Release date
2021-08-09
Henan Aochuang Chemical Co.,Ltd.
Product
2-Amino-6-methyl-5-nitropyridine 22280-62-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-18

22280-62-2, 2-Amino-6-methyl-5-nitropyridineRelated Search:

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  • 2-Amino-5-nitro-6-methylpyridi
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  • 2-Amino-6-methyl-5-nitropyridine, 6-Amino-3-nitro-2-picoline
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  • 6-Amino-2-methyl-3-nitropyridine &gt
  • 2-Amino-6-methyl-5-nitropyridine ISO 9001：2015 REACH
  • 22280-62-2
  • Pyridine
  • Pyridines derivates
  • Pyridine series
  • Amino-pyridine series
  • Pyridines
  • Amines
  • Boronic Acid