2-Methyl-3-nitropyridine

Product Name: 2-Methyl-3-nitropyridine
CAS No.: 18699-87-1
Chemical Name: 2-Methyl-3-nitropyridine
Synonyms: 3-NITROPICOLINE;3-NITRO-2-PICOLINE;2-Methyl-3-nitropyri;2-METHYL-3-NITROPYRIDINE;3-NITRO-2-METHYLPYRIDINE;2-Methxy-3-nitropyridine;Pyridine, 2-Methyl-3-nitro-;2-METHYL-3-NITROPYRIDINE 95%;Pyridine, 2-methyl-3-nitro- (9CI);2-Methyl-3-nitropyridine ISO 9001：2015 REACH
CBNumber: CB4150688
Molecular Formula: C6H6N2O2
Formula Weight: 138.12
MOL File: 18699-87-1.mol

More

Less

2-Methyl-3-nitropyridine Property

Melting point:: 32-33°
Boiling point:: 86°C/5mmHg(lit.)
Density: 1.246±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: soluble in Methanol
form: powder to lump
pka: 1.92±0.10(Predicted)
color: Light yellow to Brown
InChI: InChI=1S/C6H6N2O2/c1-5-6(8(9)10)3-2-4-7-5/h2-4H,1H3
InChIKey: CCFGTKQIRWHYTB-UHFFFAOYSA-N
SMILES: C1(C)=NC=CC=C1[N+]([O-])=O
CAS DataBase Reference: 18699-87-1(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
HazardClass: IRRITANT
HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: M2548
Product name: 2-Methyl-3-nitropyridine
Purity: >98.0%(GC)
Packaging: 1g
Price: $31
Updated: 2024/03/01

TCI Chemical

Product number: M2548
Product name: 2-Methyl-3-nitropyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $93
Updated: 2024/03/01

TRC

Product number: M320425
Product name: 2-Methyl-3-nitropyridine
Packaging: 1g
Price: $120
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H55-1-67
Product name: 2-Methyl-3-nitropyridine
Packaging: 25g
Price: $200
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H55-1-67
Product name: 2-Methyl-3-nitropyridine
Packaging: 5G
Price: $60
Updated: 2021/12/16

More

Less

2-Methyl-3-nitropyridine Chemical Properties,Usage,Production

Uses

2-Methyl-3-nitropyridine is used as a starting reagent to synthesize 3-substituted-4 or 6-azaindoles, and is also used as a reagent to prepare 3-azaindolyl-4-arylmalemides (compounds that exhibit antiproliferative activity).

Reactions

2-Methyl-3-nitropyridine could be used to synthesize dichloro-(3-nitro-2-pyridyl)methylphosphonic dichloride. The chlorination of 2-methyl-3-nitropyridine using a mixture of PCl5 in POCl3[1].

Synthesis Reference(s)

Tetrahedron, 54, p. 6311, 1998 DOI: 10.1016/S0040-4020(98)00328-7
Journal of Heterocyclic Chemistry, 29, p. 359, 1992 DOI: 10.1002/jhet.5570290213
Synthetic Communications, 20, p. 2965, 1990 DOI: 10.1080/00397919008051513

Synthesis

Suzuki Reaction. A mixture of 2-chloro-3-nitro-pyridine 1 (793 mg, 5 mmol), methylboronic acid (329 mg, 5.5 mmol), Pd(PPh3) 4 (578 mg, 0.5 mmol) and K2CO 3 (2.073 g, 15 retool) in dioxane (25 mL) was refluxed for 2 days, then cooled to room temperature and filtered. The solvent was removed and the residue was isolated by chromatography (hexanes-EtOAc = 1:1) to provide 623 mg (90%) of 2-methyl-3-nitropyridine[2].

References

[1] Amrane D, et al. "Dichloro{4-(4-chlorophenoxy)phthalazin-1-yl} methylphosphonic dichloride." Molbank (2022).
[2] Niu, Chuansheng , et al. "Synthesis of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP)." 54.23(1998):6311-6318.

2-Methyl-3-nitropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-Methyl-3-nitropyridine Suppliers

Americas 1 China 201 Europe 2 Germany 2 India 15 Japan 1 Switzerland 1 United Kingdom 5 United States 31 Global 259

Jiangyin Jufeng Biotechnology Co., Ltd

Tel: 13906113265
Email: 986329407@qq.com
Country: China
ProdList: 45
Advantage: 58

Hunan Caiya Biological Technology Co., Ltd

Tel: 15580017485
Email: 2036676503@qq.com
Country: China
ProdList: 91
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12438
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

More

Less

View Lastest Price from 2-Methyl-3-nitropyridine manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Methyl-3-nitropyridine 18699-87-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-22

Dideu Industries Group Limited

Product: 2-Methyl-3-nitropyridine 18699-87-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-08

Career Henan Chemical Co

Product: 2-Methyl-3-nitropyridine 18699-87-1
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2018-08-03

18699-87-1, 2-Methyl-3-nitropyridineRelated Search:

2,6-Lutidine Azamethiphos Methyl acetate METSULFURON METHYL Bensulfuron methyl Kresoxim-methyl Methylparaben 2,4,6-Collidine Methyl acrylate 2-Bromo-5-nitropyridine Thiophanate-methyl 4-Methylpyridine Methyl nitrotoluene Parathion-methyl 2-Methyl-4-nitropyridine 2-AMINO-5-NITRO-6-PICOLINE (2-AMINO-6-METHYL-5-NITROPYRIDINE) Methyl bromide

3-NITRO-2-PICOLINE

3-NITRO-2-METHYLPYRIDINE

2-METHYL-3-NITROPYRIDINE

2-Methyl-3-nitropyri

Pyridine, 2-methyl-3-nitro- (9CI)

3-Nitro-2-methylpyridine 3-Nitro-2-picoline

2-METHYL-3-NITROPYRIDINE 95%

3-NITROPICOLINE

Pyridine, 2-Methyl-3-nitro-

2-Methyl-3-nitropyridine ISO 9001：2015 REACH

2-Methxy-3-nitropyridine

18699-87-1

186998-87-1

69585-69-3

8699-87-1

Pyridines

Pyridine

NITRO