ChemicalBook > CAS DataBase List > TAPS

TAPS

Product Name
TAPS
CAS No.
29915-38-6
Chemical Name
TAPS
Synonyms
TAP;3-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-PROPANESULFONIC ACID;TAPS;TAPS,99%;TAPS,min;TAPS BIOXTRA;TAPS, ULTROL;Taps, puriss;TAPS ULTRAPURE;TAPS SIGMAULTRA
CBNumber
CB2433242
Molecular Formula
C7H17NO6S
Formula Weight
243.28
MOL File
29915-38-6.mol
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TAPS Property

Melting point:
230-235 °C (dec.)
Density 
1.4290 (rough estimate)
refractive index 
1.6370 (estimate)
Flash point:
110 °C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
H2O: 1 M at 20 °C, clear, colorless
form 
Solid
pka
8.55; pKa (37°): 8.1; pKa2 (25°): 8.28
color 
White
Odor
Odorless
PH Range
7.7 - 9.1
Water Solubility 
Soluble
Merck 
13,9148
BRN 
2452420
Stability:
Stable. Incompatible with strong oxidizing agents
InChIKey
YNLCVAQJIKOXER-UHFFFAOYSA-N
CAS DataBase Reference
29915-38-6(CAS DataBase Reference)
EPA Substance Registry System
1-Propanesulfonic acid, 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (29915-38-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29221980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T5130
Product name
TAPS
Purity
≥99.5% (titration)
Packaging
1kg
Price
$632
Updated
2024/03/01
Sigma-Aldrich
Product number
394675
Product name
TAPS, ULTROL
Packaging
1kg
Price
$638
Updated
2024/03/01
TCI Chemical
Product number
T0974
Product name
N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic Acid [Good's buffer component for biological research]
Purity
>98.0%(T)
Packaging
25g
Price
$31
Updated
2024/03/01
Alfa Aesar
Product number
A17754
Product name
TAPS, 99%
Packaging
25g
Price
$40.65
Updated
2024/03/01
Alfa Aesar
Product number
A17754
Product name
TAPS, 99%
Packaging
100g
Price
$97.65
Updated
2024/03/01
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TAPS Chemical Properties,Usage,Production

Description

TAPS is a zwitterionic buffering agent used in biochemistry and molecular biology. It is part of the Tris family of buffers and is useful for a pH range of 7.7 – 9.1. The members of TRIS family are tris(hydroxymethyl)aminomethane (TRIS), N-[tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid (TES), N-[tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid (TAPS), N-[tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid (TAPSO), and N-tris(hydroxymethyl)methyl-4-aminobutanesulfonic acid (TABS) buffers[1]. The solubilities of TAPS in aqueous solution decrease with increasing concentration of the salts (salting-out effect)[2]. TAPS is the preferred culture media buffer used for dinoflagellate experiments, allowing for minimal pH change and maximal growth. It is also often used in capillary electrophoresis to analyze DNA and in planar chromatography to separate dyes. TAPS may form a complex with some common metals so stability constants and concentrations should be taken into account when choosing this buffer. TAPS is capable of inhibiting connexin channels in animal cells.

Chemical Properties

White/clear crystalline powder

Uses

A zwitterionic Good's Buffer

Definition

ChEBI: N-[tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid is an organosulfonic acid.

Application

TAPS is a zwitterionic buffer used in biochemistry and molecular biology. It has a useful pH range of 7.7 - 9.1. TAPS has been utilized in capillary electrophoresis of DNA and DNA-dye complexes. Dyes can be separated by planar chromatography with electroosmotic flow containing 1 mM TAPS in the mobile phase. The stability constants of metal ions with TAPS have been investigated through the use of capillary electrophoresis. TAPS has also been shown to inhibit the activity of connexin channels. The activity of various carbonic anhydrases has been studied using TAPS physiological buffer, pKa = 8.4 at 20° C.

References

[1] Gupta B, et al. Stability Constants for the Equilibrium Models of Iron(III) with Several Biological Buffers in Aqueous Solutions. Journal of Solution Chemistry, 2013; 42: 2296–2309.
[2] Taha M, et al. New Insights into Buffer-Ionic Salt Interactions: Solubilities, Transfer Gibbs Energies, and Transfer Molar Volumes of TAPS and TAPSO from Water to Aqueous Electrolyte Solutions. Journal of Solution Chemistry, 2010; 39: 1665–1680.

TAPS Preparation Products And Raw materials

Raw materials

Preparation Products

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TAPS Suppliers

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View Lastest Price from TAPS manufacturers

Watson Biotechnology Co.,Ltd
Product
TAPS 29915-38-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20MT
Release date
2024-08-22
WUHAN FORTUNA CHEMICAL CO., LTD
Product
TAPS 29915-38-6
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%-101%
Supply Ability
1000KGS
Release date
2021-06-09
Apeloa production Co.,Limited
Product
TAPS (buffer) 29915-38-6
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
6000
Release date
2024-06-05

29915-38-6, TAPSRelated Search:

Sulfamic acid BUFFER SOLUTION PH = 6,00 (20 °C) (POTASSIUM DIHYDROGEN PHOSPHATE/SODIUM HYDROXIDE) Tris(hydroxymethyl)nitromethane Molasses Nickel bis(sulphamidate) Formaldehyde sodium bisulfite Calcium dobesilate 4-Amino-benzenesulfonic acid monosodium salt Sodium isethionate Glycine Ethylparaben CHLOROPHOSPHONAZO III BIS-Tris Sulfanilic acid Ethyl acetate Tricine Tris(hydroxymethyl)aminomethane Tris(hydroxymethyl)aminomethane acetate salt

  • 3-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-PROPANESULFONIC ACID
  • 3-[[TRIS(HYDROXYMETHYL)METHYL]AMINO]PROPANESULFONIC ACID
  • 3-[N-TRIS-(HYDROXYMETHYL)METHYLAMINO]-PROPANESULPHONIC ACID
  • 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-1-propanesulfonic acid
  • [2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]AMINO)-1-PROPANESULFONIC ACID
  • TAPS
  • TAP
  • N-TRIS(HYDROXYMETHYL)METHYL-3-AMINOPROPANESULFONIC ACID
  • N-TRIS(HYDROXYMETHYL)METHYL-3-AMINOPROPANE-SULPHONIC ACID
  • TAPS, for biochemistry, 99+%
  • TAPS,BIOLOGICALBUFFER
  • TRIS-PROPANESULFONICACID
  • N-[Tris(hydroxymethyl)methyl]-3-amino propanesulfonic acid (TAPS)
  • 3-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-PROPANESULFONIC ACID TAPS
  • TAPS ULTRAPURE
  • N-[tris(hydroxymethyl)methyl]-3-amionpropanesulfonicacid
  • N-TRIS(HYDROXYMETHYL) METHYL-3-AMINOPROPANE SULPHONIC ACID extrapure
  • N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid, [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid
  • 3-(tris(Hydroxymethyl)methylamino)propane-1-sulfonic acid
  • 3-[[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid
  • Taps, 99+%, for biochemistry
  • TAPS, for biochemistry
  • 3-[2-Hydroxy-1,1-bis(hydroxymethyl)ethylamino]propane-1-sulfonic acid
  • N-(3-Sulfopropyl)tris(hydroxymethyl)methaneamine
  • 3-[N-Tris-(hydroxymethyl)methylamino]propanesulphonic acid >99%
  • N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic Acid [Good's buffer component for biological research]
  • TAPS,99%
  • N-Tris(Hydroxymethy)methyl-3-aminopropanesulfonic acid
  • 3-[Tris(hydroxymethyl)methylamino]-1-propan
  • N-(tris(hydroxymethy
  • N-Tris (hydroxyMethy) Methyl-3-aMinopropanesulfonic acid(TAPS)
  • Tris(hydroxymethyl)methyl-3-aminopropane sulfonic acid
  • 1-Propanesulfonic acid, 3-2-hydroxy-1,1-bis(hydroxymethyl)ethylamino-
  • 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-1-propanesulfonicaci
  • tris(hydroxymethyl)methylaminopropansulfonic
  • tris(hydroxymethyl)methylaminopropansulfonicacid
  • tris-Hydroxymethyl methylamino-3-propane sulfonic acid
  • TAPS FREE ACID, BIOTECHNOLOGY PERFORMANC E CERTIFIED
  • N-(TRIS(HYDROXYMETHYL)METHYL)-3-AMINO-PR OPANESULFONIC ACI
  • TAPS SIGMAULTRA
  • TAPS, MINIMUM 99.5% (TITRATION)
  • TAPS FREE ACID CRYSTALLINE
  • Taps3-[Tris(Hydroxymethyl)Methylamino]-1-PropanesulfonicAcid
  • Taps(N-Tris[Hydroxymethyl]Methyl-3-AminoPropanesulfonicAcid)
  • 3-[N-Tris-(hydroxyMethyl)MethylaMino]propanesulphonic acid (TAPS)
  • TAPS (N-Tris[hydroxyMethyl]Methyl-3-aMinopropanesulfonic acid),Free Acid
  • 3-[N-Tris-(hydroxyMethyl)MethylaMino]propanesulphonic (TAPS)
  • 3-(tris(hydroxymethyl)methylamino)propane-1-sulphonic acid
  • Vesicle-docking protein
  • <i>N</i>-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid
  • TAPS Vetec(TM) reagent grade, 99.5%
  • N-[Tris(hydroxymethyl)metyl]-3-aminopropanesulfonic acid
  • 3-[N-Tris-(hydroxymethyl)methylamino]propanesulphonic
  • N-[Tris(hydroxymethyl)methyl]-3-aminopranesulfonic acid
  • TAPS BIOXTRA
  • TAPS, BIOPERFORMANCE CERTIFIED, CELL
  • TAPS, ULTROL
  • TAPS, ULTROL Grade - CAS 29915-38-6 - Calbiochem