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5-Amino-4-imidazolecarboxamide

Description Reference
Product Name
5-Amino-4-imidazolecarboxamide
CAS No.
360-97-4
Chemical Name
5-Amino-4-imidazolecarboxamide
Synonyms
aic;5-AMINO-1H-IMIDAZOLE-4-CARBOXAMIDE;5-AMINOIMIDAZOLE-4-CARBOXAMIDE;4-AMINOIMIDAZOLE-5-CARBOXAMIDE;5-amino-1h-imidazole-4-carboxamid;ba2756;NSC 7784;diazol-c;4-Amino-5-imodazole;Dacarbazine Impurity
CBNumber
CB2438232
Molecular Formula
C4H6N4O
Formula Weight
126.12
MOL File
360-97-4.mol
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5-Amino-4-imidazolecarboxamide Property

Melting point:
164-170 °C(lit.)
Boiling point:
234.22°C (rough estimate)
Density 
1.3659 (rough estimate)
refractive index 
1.8500 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Powder
pka
11.97±0.10(Predicted)
color 
White
Water Solubility 
Soluble in DMSO, Methanol, Water.
InChI
InChI=1S/C4H6N4O/c5-3-2(4(6)9)7-1-8-3/h1H,5H2,(H2,6,9)(H,7,8)
InChIKey
DVNYTAVYBRSTGK-UHFFFAOYSA-N
SMILES
C1NC(N)=C(C(N)=O)N=1
CAS DataBase Reference
360-97-4(CAS DataBase Reference)
EPA Substance Registry System
1H-Imidazole-4-carboxamide, 5-amino- (360-97-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
NI3910000
TSCA 
Yes
HS Code 
29332900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0000735
Product name
Dacarbazine impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000735
Price
$150
Updated
2024/03/01
Sigma-Aldrich
Product number
552410
Product name
5-Amino-4-imidazolecarboxamide
Purity
95%
Packaging
25g
Price
$193
Updated
2024/03/01
Alfa Aesar
Product number
H66184
Product name
4-Aminoimidazole-5-carboxamide, 95%
Packaging
5g
Price
$36.65
Updated
2024/03/01
Alfa Aesar
Product number
H66184
Product name
4-Aminoimidazole-5-carboxamide, 95%
Packaging
25g
Price
$140.65
Updated
2024/03/01
Alfa Aesar
Product number
H66184
Product name
4-Aminoimidazole-5-carboxamide, 95%
Packaging
100g
Price
$444
Updated
2021/12/16
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5-Amino-4-imidazolecarboxamide Chemical Properties,Usage,Production

Description

5-Amino-4-imidazolecarboxamide may be used in the synthesis of 4-(N′-benzoylcarbamoyl)amino-5-imidazolecarboxamide and 5-amino-1-β-D-ribosyl-4-imidazolecarboxamide-5′-phosphate (AICAR).It is an imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. When compounded with orotic acid, it is used to treat liver diseases.

Reference

3. Black, S. L., M. J. Black, and J. H. Mangum. "A rapid assay for 5-amino-4-imidazolecarboxamide ribotide transformylase." Analytical Biochemistry90.1(1978):397-401.

Chemical Properties

White to Off-White Solid

Uses

A metabolite of Temozolomide

Uses

4-Aminoimidazole-5-carboxamide is used as Catalytic agent, Petrochemical additive. It is metabolite of temozolomide.

Uses

5-Amino-4-imidazolecarboxamide may be used in the synthesis of 4-(N′-benzoylcarbamoyl)amino-5-imidazolecarboxamide and 5-amino-1-β-D-ribosyl-4-imidazolecarboxamide-5′-phosphate (AICAR).

Definition

ChEBI: An aminoimidazole in which the amino group is at C-5 with a carboxamido group at C-4.

5-Amino-4-imidazolecarboxamide Preparation Products And Raw materials

Raw materials

Glycinamide

Preparation Products

Temozolomide
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5-Amino-4-imidazolecarboxamide Suppliers

Belgium 1 Canada 2 China 351 Europe 2 France 2 Germany 5 India 14 Japan 1 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 2 Ukraine 1 United Kingdom 16 United States 41 Global 442
CHEMICAL LAND21
Tel
--
Fax
--
Email
sales21@chemicalland21.com
Country
South Korea
ProdList
6303
Advantage
74
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View Lastest Price from 5-Amino-4-imidazolecarboxamide manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
5-Amino-4-imidazolecarboxamide 360-97-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
20T
Release date
2024-06-11
Hangzhou ICH Biofarm Co., Ltd
Product
5-Amino-4-imidazolecarboxamide(AICA) 360-97-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99.9%min
Supply Ability
5MT
Release date
2023-06-12
Henan Aochuang Chemical Co.,Ltd.
Product
5-Amino-4-imidazolecarboxamide 360-97-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-28

360-97-4, 5-Amino-4-imidazolecarboxamideRelated Search:

ALTRENOGEST Formamide Glycine Chlorantraniliprole 4-Aminoimidazole Benzamide N,N-Dimethylformamide Betaine 4-diazo-4H-imidazole-5-carboxamide Cyano temozolomide 5-(Amino-1-(N-methyl Carbamoyl) Temozolomide Temozolomideacid 3-Amino-2-(formylamino)-3-iminopropanamide Cyanotemozolomide TeMozoloMide Metabolite - MTIC 1,5-dihydro-4H-imidazo[4,5-d]-1,2,3-triazin-4-one 1,7-DIMETHYLXANTHINE

  • 4-AMINOIMIDAZOLE-5-CARBOXAMIDE
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  • 4(5)-AMINO-5(4)-IMIDAZOLECARBOXAMIDE
  • 4(5)-AMINO-5(4)-IMIDAZOLECARBOXAMIDE (AICA) 99.0%
  • 5-Aminoimidazole-4-carboxamide,95%
  • 4(or 5)-Amino-5(or 4)-carbamoylimidazole
  • 4-Amino-5-imidazolecarboxamide ,99%
  • 5-aMino-4-iMidazolecarboxaMide, 5-aMinoiMidazole-4-carboxaMide
  • 4-AMino-5-carbaMoyliMidazole
  • NSC 7784
  • 5-AMinoiMidazole-4-carboxaMide, 97+%
  • Temozolomide Aminoimidazole Impurity
  • Imidazole-4-carboxamide, 5-amino-
  • 1H-imidazo[4,5-d][1,2,3]triazin-4(5H)-one
  • Temozolomide Impurity B
  • Temozolomideacid Impurity A: 5-Amino-4-imidazolecarboxamide
  • Dacarbazine Impurity 2(Dacarbazine EP Impurity B)
  • Temozolomide Impurity 1(EP-A)
  • aic
  • aminoimidazolecarboxamide
  • ba2756
  • diazol-c
  • 1H-Imidazole-4-carboxamide, 5-amino-
  • 5-amino-4-imidazolylcarboxamide
  • 4-Amino-5-imidazolecarboxamide monohydrate
  • AICA, 4-Amino-5-carbamoylimidazole,
  • 4-Amino-5-imodazole
  • 5-AMINI-3H-IMIDAZOLE-4-CARBOXAMIDE
  • 4-aminoimidazole-5-carboxamide hydrate
  • 4-Aminoimidzole-5-carboxamide
  • Dacarbazine impurity B CRS
  • Temozolamide Impurity C
  • 4(5)-amino-5(4)-formamide imidazole (ack)
  • Temozolomide Impurity 1（Temozolomide EP Impurity A）
  • 4-Aminoimidazole-5-carboxamide,95%
  • 4(5)-AMINO-5(4)-IMIDAZOLECARBOXAMIDE 360-97-4
  • Dacarbazine impurity BQ: What is Dacarbazine impurity B Q: What is the CAS Number of Dacarbazine impurity B Q: What is the storage condition of Dacarbazine impurity B Q: What are the applications of Dacarbazine impurity B
  • Dacarbazine USP Related Compound A
  • 4-amino-5-carboxamide imidazole
  • inhibit,5 Amino 3H imidazole 4 Carboxamide,Inhibitor,5Amino3Himidazole4Carboxamide,Endogenous Metabolite
  • 5-Amino-4-imidazolecarboxamide(AICA)
  • 4-Aminoimidazol-5-carboxamide
  • Temozolomide EP Impurity A（Dacarbazine EP Impurity B）
  • Aminoimidazole-4-carboxamide, 5-
  • Temozolamide EP Impurity-A
  • Dacarbazine Impurity
  • 360-97-4
  • 1299-72-9
  • C4H6N4OH2O
  • 12612
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