ChemicalBook > CAS DataBase List > (R)-(-)-1-Amino-2-propanol

(R)-(-)-1-Amino-2-propanol

Product Name
(R)-(-)-1-Amino-2-propanol
CAS No.
2799-16-8
Chemical Name
(R)-(-)-1-Amino-2-propanol
Synonyms
ISOPROPANOLAMINE;(R)-2-Aminopropan-1-ol;(R)-1-AMINO-2-PROPANOL;Isopropanolamin;(-)-ISOPROPANOLAMINE;(2R)-1-Amino-2-propanol;(R)-1-Aminopropane-2-ol;(R)-(-)-ISOPROPANOLAMINE;(R)-(-)-1-AMINO-2-PROPANOL;(R)-1-(Aminomethyl)ethanol
CBNumber
CB2446594
Molecular Formula
C3H9NO
Formula Weight
75.11
MOL File
2799-16-8.mol
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(R)-(-)-1-Amino-2-propanol Property

Melting point:
24-26 °C (lit.)
alpha 
-18 º (c=1.8, H2O)
Boiling point:
160 °C (lit.)
Density 
0.954 g/mL at 25 °C (lit.)
vapor density 
2.6 (vs air)
vapor pressure 
<1 mm Hg ( 20 °C)
refractive index 
n20/D 1.4482(lit.)
Flash point:
165 °F
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
form 
Liquid After Melting
pka
12.92±0.35(Predicted)
color 
Clear colorless to light yellow
Specific Gravity
0.954
optical activity
[α]20/D 23.5°, c = 1 in methanol
Water Solubility 
soluble
Sensitive 
Hygroscopic
BRN 
1718869
InChIKey
HXKKHQJGJAFBHI-GSVOUGTGSA-N
LogP
-1.127 (est)
CAS DataBase Reference
2799-16-8(CAS DataBase Reference)
NIST Chemistry Reference
2-Propanol, 1-amino-, (R)-(2799-16-8)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
23-26-36-45
RIDADR 
UN 3259 8/PG 2
WGK Germany 
1
RTECS 
UA5775000
F 
10-34
Autoignition Temperature
635 °F
HazardClass 
8
PackingGroup 
III
HS Code 
29221990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
238856
Product name
(R)-(?)-1-Amino-2-propanol
Purity
98%
Packaging
1g
Price
$25.55
Updated
2025/07/31
Sigma-Aldrich
Product number
238856
Product name
(R)-(?)-1-Amino-2-propanol
Purity
98%
Packaging
5g
Price
$178
Updated
2025/07/31
TCI Chemical
Product number
A0974
Product name
(R)-(-)-1-Amino-2-propanol
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$28
Updated
2025/07/31
TCI Chemical
Product number
A0974
Product name
(R)-(-)-1-Amino-2-propanol
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$79
Updated
2025/07/31
TCI Chemical
Product number
A0974
Product name
(R)-(-)-1-Amino-2-propanol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$234
Updated
2025/07/31
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(R)-(-)-1-Amino-2-propanol Chemical Properties,Usage,Production

Chemical Properties

Colorless to light yellow liqui

Uses

(R)-(-)-1-Amino-2-propanol is a useful research intermediate used in the synthesis of other bioactive small molecules with pharmaceutical applications.

Definition

ChEBI: A 1-aminopropan-2-ol that has R-configuration.

Synthesis

72-19-5

2799-16-8

GENERAL STEPS: Example 2 Synthesis of (R)-1-amino-2-propanol. To a 500 mL reaction vessel was added L-threonine (10 g, 0.839 mol), 2-cyclohexen-1-one (8.07 g, 0.084 mol) and polyethylene glycol. The mixture was stirred under a nitrogen atmosphere at 150-160 °C. After 72 h, the reaction was judged complete when the crystals were completely dissolved and the mixture appeared homogeneous. The yield of (R)-1-amino-2-propanol was confirmed to be 80.6% by gas chromatographic analysis. Subsequently, the reaction solution was distilled under reduced pressure at the same temperature and the fractions were collected at 54-62 °C (1-20 hPa) to give (R)-1-amino-2-propanol (44.4 g, yield: 70.4%, chemical purity: 99.0%, optical purity: 99.9% ee).

References

[1] Chemistry Letters, 1986, p. 893 - 896
[2] Synthetic Communications, 1994, vol. 24, # 10, p. 1381 - 1387
[3] Patent: US2005/222430, 2005, A1. Location in patent: Page/Page column 2
[4] Synthetic Communications, 1993, vol. 23, # 8, p. 1071 - 1074

(R)-(-)-1-Amino-2-propanol Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(-)-1-Amino-2-propanol Suppliers

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View Lastest Price from (R)-(-)-1-Amino-2-propanol manufacturers

TAIZHOU DKD CHEMICAL CO., LTD.
Product
(R)-(-)-1-Amino-2-propanol 2799-16-8
Price
US $0.00/kg
Min. Order
25kg
Purity
99%
Supply Ability
20 tons
Release date
2022-11-09
Career Henan Chemical Co
Product
(R)-(-)-1-Amino-2-propanol 2799-16-8
Price
US $1.00/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
2000kg
Release date
2019-08-05

2799-16-8, (R)-(-)-1-Amino-2-propanolRelated Search:

EC 2.6.1.2 Glycine Betaine 1-Propanol L-carnitine 5-(TERT-BUTYL)-2-IODO-1,3-DIMETHYLBENZENE Acetaminophen Glucosamine Sulfamic acid Isopropyl alcohol ALTRENOGEST Triisopropanolamine Levamisole Levodopa Aminopyrine L-Alaninol (R)-(-)-1-METHOXY-2-PROPANOL (R)-(+)-Propylene carbonate

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  • China biggest manufacturer (R)-(-)-1-Amino-2-propanol 2799-16-8
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  • Chiral Building Blocks
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  • Asymmetric Synthesis
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  • AMINE
  • Simple Alcohols (Chiral)
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  • Chiral Compound
  • chiral
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