(R)-(+)-Propylene carbonate

Product Name: (R)-(+)-Propylene carbonate
CAS No.: 16606-55-6
Chemical Name: (R)-(+)-Propylene carbonate
Synonyms: R-Prpylene Carbonate;(R)-PROPYLENE CARBONATE;(R)-Propandiolcarbonate;(R)-PropyleneCarbonate>(R)-(+)-PROPYLENE CARBONATE;(R)-1,2-PROPYLENE CARBONATE;(R)-1,2-PROPANEDIOL CARBONATE;Tenofovirdisoproxil Impurity 38;(R)-Propylene Carbonate,99%e.e.;(R)-(+)-1,2-PROPYLENE CARBONATE
CBNumber: CB3783423
Molecular Formula: C4H6O3
Formula Weight: 102.09
MOL File: 16606-55-6.mol

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(R)-(+)-Propylene carbonate Property

Boiling point:: 240 °C(lit.)
Density: 1.189 g/mL at 25 °C(lit.)
vapor pressure: 0.59 psi ( 20 °C)
refractive index: n20/D 1.422(lit.)
Flash point:: >230 °F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform (Sparingly)
form: Oil
color: Clear Colourless to Pale Yellow
Specific Gravity: 1.189
optical activity: [α]20/D +2°, neat
Water Solubility: 175 g/L (25 ºC)
InChI: InChI=1S/C4H6O3/c1-3-2-6-4(5)7-3/h3H,2H2,1H3/t3-/m1/s1
InChIKey: RUOJZAUFBMNUDX-GSVOUGTGSA-N
SMILES: O1C[C@@H](C)OC1=O
CAS DataBase Reference: 16606-55-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: FF9650000
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 540013
Product name: (R)-(+)-Propylene carbonate
Purity: 98%
Packaging: 5g
Price: $70.1
Updated: 2025/07/31

TCI Chemical

Product number: P1485
Product name: (R)-Propylene Carbonate
Purity: >98.0%(GC)
Packaging: 5g
Price: $49
Updated: 2025/07/31

TCI Chemical

Product number: P1485
Product name: (R)-Propylene Carbonate
Purity: >98.0%(GC)
Packaging: 25g
Price: $241
Updated: 2025/07/31

TRC

Product number: P836750
Product name: (R)-1,2-PropyleneCarbonate
Packaging: 1g
Price: $110
Updated: 2021/12/16

AK Scientific

Product number: J91366
Product name: (R)-4-Methyl-1,3-dioxolan-2-one
Packaging: 25g
Price: $15
Updated: 2021/12/16

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(R)-(+)-Propylene carbonate Chemical Properties,Usage,Production

Description

(R)-(+)-Propylene carbonate, also known as (R)-1,2-Propanediol cyclic carbonate, presents as a colorless to pale yellow liquid. This compound should keep the container tightly closed and stored in a cool and dark place. For best results, store under inert gas, protected from moisture, as this substance is moisture-sensitive. (R)-(+)-Propylene carbonate is incompatible with oxidizing agents and acids. This chemical causes skin irritation as well as serious eye irritation.

Chemical Properties

Colorless to light yellow liqui

Uses

(R)-1,2-Propylene Carbonate (cas# 16606-55-6) is a compound useful in organic synthesis.

Synthesis

4254-14-2

105-58-8

16606-55-6

The general procedure for the synthesis of R-propylene carbonate from (R)-1,2-propanediol and diethyl carbonate was as follows: (R)-1,2-propanediol (38.05 kg, 500 mol) was added to a glass-lined reactor, followed by the addition of diethyl carbonate (70.88 kg, 600 mol) and sodium ethoxide (3.4 kg, 50 mol). The reaction mixture was heated to 105-110 °C and maintained for 8 hours. After completion of the reaction, unreacted diethyl carbonate was removed by distillation under reduced pressure. After the reaction mixture was cooled to room temperature, the insoluble material was removed by filtration. Finally, the solvent was removed by evaporation of the filtrate to afford R-propylene carbonate (34.24 kg, purity ≥99%) in 90% yield.

References

[1] Patent: CN105859781, 2016, A. Location in patent: Paragraph 0011-0012
[2] Patent: US2010/216822, 2010, A1. Location in patent: Page/Page column 13
[3] Tetrahedron Letters, 1998, vol. 39, # 14, p. 1853 - 1856
[4] Patent: EP1243590, 2002, A2. Location in patent: Page 9
[5] Patent: CN102977146, 2016, B. Location in patent: Paragraph 0016; 0021; 0023

(R)-(+)-Propylene carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(+)-Propylene carbonate Suppliers

Americas 1 Belgium 3 Canada 1 China 316 China Hong Kong 1 Europe 4 Germany 8 India 21 Japan 5 South Korea 2 Switzerland 2 United Kingdom 14 United States 33 Global 411

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View Lastest Price from (R)-(+)-Propylene carbonate manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: (R)-(+)-Propylene carbonate 16606-55-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20000
Release date: 2025-07-29

Shaanxi Dideu New Materials Co. Ltd

Product: (R)-(+)-Propylene carbonate 16606-55-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 10000KGS
Release date: 2025-05-26

Hebei Chuanghai Biotechnology Co., Ltd

Product: (R)-(+)-Propylene carbonate 16606-55-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-12-02

16606-55-6, (R)-(+)-Propylene carbonateRelated Search:

Propylene oxide Ammonium carbonate PROPYLENE Diallyl phthalate 1,3,2-Dioxathiane 2-oxide Barium carbonate Dimethyl carbonate Sodium carbonate Allyl acetate (S)-(-)-Propylene Carbonate (R)-(-)-1-Amino-2-propanol (R)-(-)-1-METHOXY-2-PROPANOL Diethyl phosphite Calcium carbonate rac-Tenofovir-d7 Chloromethyl isopropyl carbonate ChloroMethyl Propyl Carbonate (S)-Tenofovir

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C5H7O6

Organic Building Blocks

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Dioxanes & Dioxolanes

Chiral Building Blocks

Glycidyl Compounds, etc. (Chiral)

Carbonates

Asymmetric Synthesis

chiral

Chiral Compounds

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Dioxanes & Dioxolanes

Dioxolanes

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Synthetic Organic Chemistry

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