6-PHENYL-2-THIOURACIL

Product Name: 6-PHENYL-2-THIOURACIL
CAS No.: 36822-11-4
Chemical Name: 6-PHENYL-2-THIOURACIL
Synonyms: PHENYLTHIOURACIL;BUTTPARK 45\01-77;6-phenylthiouracil;6-PHENYL-2-THIOURACIL;6-Phenyl-2-thiouracil>6-Phenyl-2-thiouracil(4-);6-Phenyl-2-thiouracil ,98%;6-PHENYL-2-THIOURACIL (4-) 98+%;13C,15N2]-6-Phenyl-2-thiouracil;2-Mercapto-6-phenyl-4-pyrimidinol
CBNumber: CB2447915
Molecular Formula: C10H8N2OS
Formula Weight: 204.25
MOL File: 36822-11-4.mol

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6-PHENYL-2-THIOURACIL Property

Melting point:: 263-264.5 °C(Solv: water (7732-18-5))
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Aqueous Base (Slightly), DMSO (Slightly)
form: Solid
pka: 7.29±0.20(Predicted)
color: White to Off-White
biological source: synthetic (organic)
CAS DataBase Reference: 36822-11-4(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P3252
Product name: 6-Phenyl-2-thiouracil
Purity: ≥95%
Packaging: 1g
Price: $233
Updated: 2025/07/31

Sigma-Aldrich

Product number: 05594
Product name: 6-Phenyl-2-thiouracil
Purity: analytical standard
Packaging: 100mg
Price: $89.5
Updated: 2022/05/15

TCI Chemical

Product number: P0236
Product name: 6-Phenyl-2-thiouracil
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $120
Updated: 2025/07/31

TCI Chemical

Product number: P0236
Product name: 6-Phenyl-2-thiouracil
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $360
Updated: 2025/07/31

TRC

Product number: P337105
Product name: 6-Phenyl-2-thiouracil
Packaging: 1g
Price: $305
Updated: 2021/12/16

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6-PHENYL-2-THIOURACIL Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

6-Phenyl-2-thiouracil is a thyreostatic (thyroid hormone) agent that may be used as a reference material in thyreostatic drug separation and detection technologies such as capillary electrophoresis, HPLC, or gas chromatography.

Definition

ChEBI: 6-Phenyl-2-thiouracil is a member of pyrimidines.

Synthesis

94-02-0

17356-08-0

36822-11-4

To a solution of ethyl benzoylacetate (2 g, 10.41 mmol) in ethanol (15 mL) was added sodium ethoxide (7 mL, 18.7 mmol) and compound (CAS:17356-08-0) (1.18 g, 15.61 mmol). The reaction mixture was stirred under reflux conditions overnight. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in water, the pH was adjusted to 3 with acid and extracted with ethyl acetate (3 x 20 mL). The organic phases were combined, washed with brine and dried over anhydrous sodium sulfate. The crude product was purified by fast column chromatography using dichloromethane/methanol (2.5%) as eluent to afford 2-mercapto-6-phenyl-4-hydroxypyrimidine (500 mg, 2.44 mmol) as a white solid in 24% yield.

References

[1] Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 1999, vol. 54, # 6, p. 788 - 798
[2] Synthetic Communications, 2002, vol. 32, # 6, p. 851 - 855
[3] Patent: WO2016/30534, 2016, A1. Location in patent: Page/Page column 109
[4] Journal of Medicinal Chemistry, 2018, vol. 61, # 3, p. 745 - 759
[5] Journal fuer Praktische Chemie (Leipzig), 1893, vol. <2> 47, p. 203

6-PHENYL-2-THIOURACIL Preparation Products And Raw materials

Raw materials

Ethanol Sodium Acetophenone Ethyl acetate Hydrochloric acid Acetic acid Methanol Diethyl carbonate Isopropyl alcohol Thiourea

Preparation Products

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6-PHENYL-2-THIOURACIL Suppliers

Americas 1 Canada 1 China 80 Europe 1 Germany 3 India 3 Japan 1 Switzerland 1 United Kingdom 11 United States 17 Global 119

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View Lastest Price from 6-PHENYL-2-THIOURACIL manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 6-Phenyl-2-thiouracil 36822-11-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-05-14

Career Henan Chemical Co

Product: 6-PHENYL-2-THIOURACIL 36822-11-4
Price: US $9.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-03

36822-11-4, 6-PHENYL-2-THIOURACILRelated Search:

6-PHENYL-2-THIOURACIL 4-Phenylpyrimidine Uracil 2-Thiouracil 3-(4-OXO-6-PHENYL-1,4-DIHYDRO-PYRIMIDIN-2-YLSULFANYL)-PROPIONIC ACID 2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE (4-OXO-6-PHENYL-1,4-DIHYDRO-PYRIMIDIN-2-YL-SULFANYL)-ACETIC ACID BUTTPARK 14\02-43 N-(2,6-DIMETHYLPHENYL)-2-[(4-OXO-6-PHENYL-1,4-DIHYDROPYRIMIDIN-2-YL)THIO]ACETAMIDE BUTTPARK 14\02-47 4-HYDROXY-6-PHENYL-2-([3-(TRIFLUOROMETHYL)BENZYL]SULFANYL)-5-PYRIMIDINECARBONITRILE 2-[(2-PHENOXYETHYL)THIO]-6-PHENYLPYRIMIDIN-4(1H)-ONE BUTTPARK 13\01-50 BUTTPARK 14\02-41 BUTTPARK 17\09-58 4-HYDROXY-2-(METHYLSULFANYL)-6-PHENYL-5-PYRIMIDINECARBONITRILE 4-HYDROXY-2-(METHYLTHIO)-6-PHENYLPYRIMIDINE BUTTPARK 14\02-45

4-HYDROXY-2-MERCAPTO-6-PHENYLPYRIMIDINE

6-HYDROXY-2-MERCAPTO-4-PHENYLPYRIMIDINE

6-PHENYL-2-THIOURACIL

2-MERCAPTO-6-PHENYL-PYRIMIDIN-4-OL

BUTTPARK 45\01-77

6-phenylthiouracil

PHENYLTHIOURACIL

6-PHENYL-2-THIOURACIL (4-) 98+%

6-Phenyl-2-thiouracil(4-)

6-Phenyl-2-thiouracil ,98%

1,2-Dihydro-6-phenyl-2-thioxopyrimidine-4(3H)-one

2-Mercapto-6-phenyl-4-pyrimidinol

6-Phenyl-2(1H)-thioxopyrimidine-4(3H)-one

6-Phenyl-2-thioxo-1,2-dihydropyrimidine-4(3H)-one

4-Phenyl-2-mercapto-6-hydroxypyrimidine

2-Mercapto-6-phenylpyriMidin-4-one

2-Mercapto-4-phenyl-6-pyrimidinol

2-mercapto-6-phenylpyrimidin-4(1H)-one(SALTDATA: FREE)

2-Mercapto-4-hydroxy-6-phenylpyriMidine(Ⅰ)

4(1H)-Pyrimidinone, 2,3-dihydro-6-phenyl-2-thioxo-

6-phenyl-2-sulfanylidene-1H-pyrimidin-4-one

6-phenyl-2-thioxo-1H-pyrimidin-4-one

6-Phenyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone

6-phenyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

6-Pyrimidinol, 2-mercapto-4-phenyl-

6-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one

6-Phenyl-2-thiouracil&gt

13C,15N2]-6-Phenyl-2-thiouracil

6-Phenyl-2-thiouracil in acetonitrile

36822-11-4

C10H8N2OS

BioChemical

Biochemicals and Reagents

Nucleoside Analogs

Nucleosides, Nucleotides, Oligonucleotides

Biochemistry

Nucleobases and their analogs

Nucleosides, Nucleotides & Related Reagents

Biochemicals and Reagents

Nucleoside Analogs

Nucleosides, Nucleotides, Oligonucleotides